Arp2/3 complex
Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections
... the Arp2/3 complex, we modified a previously developed cell-free protein reconstitution assay ...the Arp2/3 complex, profilin, cofilin, gelsolin, and ...the Arp2/3 ...
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Identification and Characterization of Schizosaccharomyces pombe asp1+, a Gene That Interacts with Mutations in the Arp2/3 Complex and Actin
... the Arp2/ 3 ...(lane 3); asp1- D1 carrying pREP1asp1 grown in the presence of thiamine, promoter repressed (lane 4); or asp1-D1 carrying pREPasp1 grown in the absence of thia- mine, promoter induced ...
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Dissection of Arp2/3 Complex Actin Nucleation Mechanism and Distinct Roles for Its Nucleation-Promoting Factors in Saccharomyces cerevisiae
... association with Arp2/3 complex. This could help re- cycle stronger NPFs after nucleation events and possibly stabilize filament branch points. Alternatively, this could serve as a competition ...
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BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis
... bovine Arp2/3 complex in vitro, indicating that these are bona fide WAVE/Scar homologs (Frank et ...WAVE/Scar complex subunits (Nap1, PIR121/Sra-1, Abi and HSPC300) are also present in ...
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Arp2/3 Complex Is Expressed in Oral Squamous Cell Carcinoma: An Immunohistochemical Study of 88 Cases
... tumors Arp2/3 expression isposi- tively correlated to tumor size, depth of invasion, venous invasion and higher stage disease [13] [14] [15] [16] ...adenocarcinomas Arp2/3 ex- pression was ...
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Transient localization of the Arp2/3 complex initiates neuronal dendrite branching in vivo
... nucleator complex Actin-Related Protein 2/3 (Arp2/3) and give rise to dendrite spines (Korobova and Svitkina, 2010; Saarikangas et ...The Arp2/3 complex is a strong ...
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ARP2/3 complex is required for directional migration of neural stem cell-derived oligodendrocyte precursors in electric fields
... After the EF stimulation, the NSC-OPCs and oligospheres were fixed with 4% paraformaldehyde and permeabilized with 0.2% Triton X-100. Cells were exposed to a blocking solution—10% horse serum and 1% bovine serum albumin ...
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The Arp2/3 complex, UNC-115/abLIM, and UNC-34/Enabled regulate axon guidance and growth cone filopodia formation in Caenorhabditis elegans
... The Arp2/3 complex has been implicated in axon path- finding in ...the Arp2/3 complex and its regulators WAVE/Scar and Kette are required for proper axon pathfinding [9], and in ...
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The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway
... LegK2 specifically interacts with host cell ARP2/3 complex sub- units. To identify host cell proteins that interact with LegK2, we performed yeast two-hybrid screening. The construct pGBKT7- legK2, ...
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A Ride with Listeria monocytogenes: A Trojan Horse
... Apr2/3 complex has been found to organize signals of actin cytoskeletons and initiate actin assembly because of its specific ...The Arp2/3 complex is comprised of the actin related ...
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The Role of the Exocyst in Exocytosis and Cell Migration
... the Arp2/3 ...the Arp2/3 complex from cells with various levels of invasiveness (HeLa cells, the parental MDA-MB-231 cells, and the Y527F c-Src cells) and examined the interaction of ...
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Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML
... of ARP2/3-complex acti- vation and therefore a requirement of WASP protein family membership, we would suggest to also group these proteins to the WASP family because of the strong sequence homology ...
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Integrin signaling to the actin cytoskeleton.pdf
... the Arp2/3 complex are members of the Wiskott–Aldrich syndrome protein (WASP) family of proteins, including WASP, N-WASP and WAVE/SCAR ...the Arp2/3 complex after they have ...
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A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast
... Bee1p–Vrp1p–myosin-I complex must also be activated through phosphorylation by PAKs, which is required for the motor activity of these myosins (Maruta and Korn, 1977; Wu et ...the Arp2/3 ...
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2329.full.pdf
... Our results provide substantial insight into the cellular and molecular mechanisms of haptotaxis, leading us to develop a working model of this process (Fig. 7E). Cells encountering a gradient in the ECM (i.e. in the ...
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The Putative Pocket Protein Binding Site of Autographa californica Nucleopolyhedrovirus BV/ODV-C42 Is Required for Virus-Induced Nuclear Actin Polymerization
... Nuclear filamentous actin (F-actin) is essential for nucleocapsid morphogenesis of lepidopteran nucleopoly- hedroviruses. Previously, we had demonstrated that Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ...
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SCAR/WAVE and Arp2/3 are crucial for cytoskeletal remodeling at the site of myoblast fusion
... the Arp2/3 complex in these ...the Arp2/3 complex, revealed a moderate myoblast fusion defect, similar to the defect seen in a SCAR zygotic loss-of-function ...the ...
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Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells
... the Arp2/3 complex through IRSp53 (53, 58), an adaptor protein that also binds Rac1 and Wave2, inducing actin branching and lamel- lipodium formation (58, ...signaling complex has an effect on ...
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Elucidating Key Motifs Required for Arp2/3-Dependent and Independent Actin Nucleation by Las17/WASP.
... To determine the stage of endocytosis requiring the basic residues for actin nucleation, the relative behaviours of two endocytic markers was investigated. Sla1-GFP was used as a reporter of early endocytosis and ...
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Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity
... the Arp2/3 complex in actin nucleation in T cells ...the Arp2/3 com- plex, forming an interface together with ARPC5 and Arp2 that is critical for actin nucleation ...the ...
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