Artemisinin Based Combination
Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin based combination therapy
... of artemisinin-based combination therapy (ACT) as first-line malaria ...burden. Combination with a second agent improves treatment outcomes and minimizes the possi- bility of selecting ...
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Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework
... to artemisinin-based combination therapies ...misinin-based combination therapies recommended by the World Health Organisation (WHO) were available ...
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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine
... Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission. Artemisinin- based combination therapy (ACT) ...
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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine
... [7]. Artemisinin-based combination therapy (ACT) is emerging as the best option in this context, particularly in settings where there are concerns about chloroquine- resistant ...in ...
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From chloroquine to artemisinin based combination therapy: the Sudanese experience
... Changing drug policy is complex. Limiting factors are high cost, limited knowledge and lack of public awareness on the effectiveness and safety of ACTs in addition to operational issues [34-36]. Changing from CQ in ...
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Subsidising artemisinin-based combination therapy in the private retail sector
... Malaria is a major cause of ill health and death in Africa (WHO 2012). Uncomplicated Plasmodium falciparum malaria is the com- monest form of the disease and accounts for most of the malaria cases and deaths (WHO 2012). ...
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Artemisinin-based combination therapy for treating uncomplicated malaria (Review)
... the artemisinin derivatives (and rapid elimination from the blood) means that patients must take the drug for at least seven days (Meshnick 1996; Adjuik ...resistance. Artemisinin derivatives are therefore ...
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Efficacy and safety of artemisinin based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania
... of artemisinin-based combination ther- apy (ACT) for the treatment of uncomplicated malaria, the Ministry of Health, Community Development, Gender, Elderly and Children of Tanzania introduced ...
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Stabilizing supply of artemisinin and artemisinin based combination therapy in an era of wide spread scale up
... for artemisinin-based combination therapy (ACT) has grown sharply since its recommendation by the World Health Organization in ...a combination of financing and programmatic uncertainties, ...
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Subsidizing artemisinin-based combination therapies: a preliminary investigation of the Affordable Medicines Facility – malaria
... The Affordable Medicines Facility – malaria (AMFm) is a financing mechanism hosted by The Global Fund to Fight AIDS, Tuberculosis and Malaria (GF) and designed to expand access to the best malaria treatments, which at ...
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Artemisinin based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia
... introduced artemisinin-based combination therapy (ACT) into its national malaria drug policy for uncomplicated Plasmodium falciparum ...cases. Combination therapy for ...the combination ...
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Willingness and ability to pay for artemisinin based combination therapy in rural Tanzania
... [2,3]. Artemisinin-based combination therapy (ACT) is, therefore, recommended as the first-line anti-malarial treatment strategy in most parts of sub-Saharan Africa ...of artemisinin ...
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Efficacy and safety of artemisinin based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial
... ACT: artemisinin-based combination therapy; AE: adverse events; AL: fixed dose combination of 20 mg + 120 mg artemether and lumefantrine; AL + Pq: fixed dose combination artemether and ...
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Adherence to artemisinin based combination therapy for the treatment of malaria: a systematic review of the evidence
... ACT: Artemisinin-based combination therapy; AL: Artemether-lumefantrine; AMFm: Affordable Medicines Facility – malaria; AQAS: Amodiaquine-artesunate co-formulated; AQ + AS: Amodiaquine plus ...
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Routine delivery of artemisinin based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study
... years, artemisinin-based combination therapy (ACT) has been introduced for malaria case management in nearly all countries in sub-Saharan Africa, based mostly on its clin- ical efficacy at the ...
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Adherence to prescribed artemisinin based combination therapy in Garissa and Bunyala districts, Kenya
... The study was undertaken in two districts: Bunyala dis- trict, Western Province, close to Lake Victoria with per- ennial malaria transmission and community-based parasite prevalence among children in excess of 40% ...
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Efficacy of non artemisinin and artemisinin based combination therapies for uncomplicated falciparum malaria in Cameroon
... A total of 1,401 patients were enrolled in our series of studies (1,337 in randomized studies and 64 in a single non-randomized AS-AQ study in Maroua). All analysed data are presented in a CONSORT format in Fig. 1[14]. ...
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Prospective observational study to evaluate the clinical safety of the fixed dose artemisinin based combination Eurartesim® (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania
... Data were double-entered and verified using OpenClinica software. Statistical analyses were performed using the soft- ware package STATA® (version 11. 2). Descriptive analyses were conducted of all data recorded at study ...
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Predicting Global Fund grant disbursements for procurement of artemisinin based combination therapies
... and artemisinin cultivation must predict demand for ACT on a product- and dosage-specific ...and artemisinin require- ments, may be performed using information contained in Global Fund proposals specifying ...
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Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria
... the artemisinin derivatives but some resistance among ...2009). Artemisinin derivatives are generally reported as being well-toler- ated, and the safety profile of ACTs may be largely determined by the ...
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