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Artemisinin-Based Combination Therapy

Stabilizing supply of artemisinin and artemisinin based combination therapy in an era of wide spread scale up

Stabilizing supply of artemisinin and artemisinin based combination therapy in an era of wide spread scale up

... for artemisinin-based combination therapy (ACT) has grown sharply since its recommendation by the World Health Organization in ...a combination of financing and programmatic ...

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Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin based combination therapy

Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin based combination therapy

... of artemisinin-based combination therapy (ACT) as first-line malaria ...burden. Combination with a second agent improves treatment outcomes and minimizes the possi- bility of selecting ...

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Artemisinin-based combination therapy for treating uncomplicated malaria (Review)

Artemisinin-based combination therapy for treating uncomplicated malaria (Review)

... the artemisinin derivatives (and rapid elimination from the blood) means that patients must take the drug for at least seven days (Meshnick 1996; Adjuik ...resistance. Artemisinin derivatives are therefore ...

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Adherence to artemisinin based combination therapy for the treatment of malaria: a systematic review of the evidence

Adherence to artemisinin based combination therapy for the treatment of malaria: a systematic review of the evidence

... ACT: Artemisinin-based combination therapy; AL: Artemether-lumefantrine; AMFm: Affordable Medicines Facility – malaria; AQAS: Amodiaquine-artesunate co-formulated; AQ + AS: Amodiaquine plus ...

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Efficacy and safety of artemether lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin based combination therapy in mainland Tanzania

Efficacy and safety of artemether lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin based combination therapy in mainland Tanzania

... : artemisinin-based combination therapy; AL: artemether-lumefantrine; ASAQ: artesunate + amo- diaquine; AS + SP: artesunate + sulfadoxine/pyrimethamine; CDC: Centers for Disease Control and ...

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Artemisinin based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia

Artemisinin based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia

... introduced artemisinin-based combination therapy (ACT) into its national malaria drug policy for uncomplicated Plasmodium falciparum ...cases. Combination therapy for ...the ...

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From chloroquine to artemisinin based combination therapy: the Sudanese experience

From chloroquine to artemisinin based combination therapy: the Sudanese experience

... was based for decades on vector control, through spraying with ...to artemisinin-based combination therapy (ACTs), both as first- and second-line treatment for the manage- ment of ...

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Willingness and ability to pay for artemisinin based combination therapy in rural Tanzania

Willingness and ability to pay for artemisinin based combination therapy in rural Tanzania

... [2,3]. Artemisinin-based combination therapy (ACT) is, therefore, recommended as the first-line anti-malarial treatment strategy in most parts of sub-Saharan Africa ...of artemisinin ...

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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine

Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine

... : artemisinin-based combination therapy; AE: adverse events; AL: fixed dose combination of 20 + 120 mg artemether and lumefantrine with con- comitant use of primaquine; ANVISA: National ...

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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine

Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine

... ACT: Artemisinin-based combination therapy; AE: Adverse events; AL: Fixed dose combination of 20 + 120 mg artemether and lumefantrine with concomitant use of primaquine; ANVISA: ...

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Efficacy and safety of artemisinin based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial

Efficacy and safety of artemisinin based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial

... of artemisinin-based combination therapy regimens in this population offers the opportunity to treat all species of malaria with the same regimen, simplifying pro- tocols for malaria control ...

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Efficacy and safety of artemisinin based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania

Efficacy and safety of artemisinin based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania

... : artemisinin-based combination therapy; ACPR: adequate clinical and parasitological response; AL: artemether/lumefantrine; ASAQ: artesunate/amo- diaquine; DHAPQ: ...

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Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework

Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework

... One participant was concerned about the urban-poor populations who have to make a choice between long waiting times and unreliable public health services ver- sus reliable but unaffordable services in the private sec- ...

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Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria

Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria

... the artemisinin derivatives but some resistance among ...2009). Artemisinin derivatives are generally reported as being well-toler- ated, and the safety profile of ACTs may be largely determined by the ...

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Subsidising artemisinin-based combination therapy in the private retail sector

Subsidising artemisinin-based combination therapy in the private retail sector

... Decisions to incorporate retail sector ACT subsidies into national malaria control programmes need to involve consideration of in- dividual country contexts (which could include local malaria epi- demiology, public ...

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Adherence to prescribed artemisinin based combination therapy in Garissa and Bunyala districts, Kenya

Adherence to prescribed artemisinin based combination therapy in Garissa and Bunyala districts, Kenya

... Disadvantages of AL include the large number of tablets that need to be taken to complete the full course of therapy. This is further complicated by the fact that the first two doses of AL need to be taken 8 hours ...

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Who continues to stock oral artemisinin monotherapy? Results of a provider survey in Myanmar

Who continues to stock oral artemisinin monotherapy? Results of a provider survey in Myanmar

... Background: Artemisinin-based combination therapy (ACT) is a key strategy for global malaria elimination ...of artemisinin-resistant malaria parasites threatens progress and continued ...

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Anti malarial prescription practices among outpatients with laboratory confirmed malaria in the setting of a health facility based sentinel site surveillance system in Uganda

Anti malarial prescription practices among outpatients with laboratory confirmed malaria in the setting of a health facility based sentinel site surveillance system in Uganda

... mended artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falcip- arum malaria in countries with resistance to older mo- notherapies ...first-line ...

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Anti malarial landscape in Myanmar: results from a nationally representative survey among community health workers and the private sector outlets in 2015/2016

Anti malarial landscape in Myanmar: results from a nationally representative survey among community health workers and the private sector outlets in 2015/2016

... Methods: This was a cross-sectional survey, which employed stratified cluster-random sampling across four regions in Myanmar. A census of community health workers (CHWs) and private outlets with potential to distribute ...

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Malaria: Knowledge, Attitudes and Acceptances of Rapid Diagnostic Test amongst Primary Healthcare Workers in Some Selected Local Government Areas, Lagos State, Nigeria

Malaria: Knowledge, Attitudes and Acceptances of Rapid Diagnostic Test amongst Primary Healthcare Workers in Some Selected Local Government Areas, Lagos State, Nigeria

... of Artemisinin - based Combination Therapy (ACT), as the first line anti- malaria treatment for Plasmodium falciparum infection in most endemic ...

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