Artemisinin combination therapy
Assessment of Treatment Failure to Artemisinin Combination Therapy (ACT) in a Tertiary Care Centre in South India
... TO ARTEMISININ COMBINATION THERAPY IN PLASMODIUM FALCIPARUM MALARIA 1)What is this study about? Following the diagnosis of severe malaria and hospitalisation,you will be initiated on Intravenous ...
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Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy
... Abstract Background: Plasmodium falciparum malaria is a significant public health problem in Comoros, and artemisinin combination therapy (ACT) remains the first choice for treating acute ...
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Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children
... and combination therapy regimens which include an artemisinin component display good ...with artemisinin combination therapy (ACT) in western ...
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Access to artemisinin combination therapy for malaria in remote areas of Cambodia
... Clearly, priority should also be given to the delivery of affordable good quality treatment through the public sec- tor. The findings in this study suggest that VMWs in par- ticular, appeared to be effective means of ...
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Cost of increasing access to artemisinin combination therapy: the Cambodian experience
... to artemisinin combination therapies (ACTs) for the treatment of Plasmodium falciparum malaria and the global community are considering setting up a global subsidy to fund their ...
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Randomized clinical trial of artemisinin versus non artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar
... after therapy was high with AQ+AS than AQ+SP treatment, even in a low transmission area such as ...AQ+AS combination, AS is rap- idly eliminated, leaving only AQ to provide post-treat- ment ...
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The influence of pregnancy on the pharmacokinetic properties of artemisinin combination therapy (ACT): a systematic review
... Results: The literature search identified 121 reports, 27 original studies were included. 829 pregnant women were included in the analysis. Comparison of the available studies showed lower maximum concentrations (C max ) ...
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Efficacy and safety of artemisinin combination therapy (ACT) for non falciparum malaria: a systematic review
... Artemisinin-based combinations with long half-lives show significantly fewer recurrent parasitaemia up to day 63. The limited evidence available supports both the use of chloroquine and an ACT for P. ovale and P. ...
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Safety monitoring of artemisinin combination therapy through a national pharmacovigilance system in an endemic malaria setting
... The apparent incidence of ADEs is far less than the results of a clinical trial conducted in Senegal. That is undoubtedly a reflection of the nature of the reporting scheme, which relies on busy nurses and other health ...
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Health worker factors associated with prescribing of artemisinin combination therapy for uncomplicated malaria in rural Tanzania
... This paper presents findings from an assessment of the quality of malaria case management and health worker factors associated with correct pre- scription of ACT for management of uncomp[r] ...
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Health Worker Factors Associated with Prescribing of Artemisinin Combination Therapy for Uncomplicated Malaria in Rural Tanzania.
... Seventy-one per cent of the patients with uncomplicated malaria seen in health facility with ACT in stock were seen by a medical assistant, clinical officer or clinical assistant, only 5[r] ...
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Treatment of Febrile illness with artemisinin combination therapy: prevalence and predictors in five African household surveys
... inappropriate artemisinin monotherapy were reported in the four countries where ACT was available and the use of halofantrine was documented in the Nigeria survey despite its ban one year earlier ...
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Field evaluation of the 22 rapid diagnostic tests for community management of malaria with artemisinin combination therapy in Cameroon
... Methods: One hundred human blood samples (50 positive and 50 negative) collected from consenting febrile patients in two health centres at Yaoundé were used for evaluation of the 22 R[r] ...
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Stabilizing supply of artemisinin and artemisinin based combination therapy in an era of wide spread scale up
... semi-synthetic artemisinin may ease some market pressures [52], the projected quantity to be produced in the short-term [12] is unlikely to create a significant rebalancing of the sup- ply ...
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From chloroquine to artemisinin based combination therapy: the Sudanese experience
... Case description Efficacy studies supporting change from CQ to ACT From 1975 to 2005, many drug efficacy studies were car- ried out in Sudan, several published in international and national scientific journals. Table 1 ...
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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine
... of artemisinin-based combination therapy and chloroquine with concomitant primaquine to treat Plasmo- dium vivax malaria in Brazil: an open label randomized clinical ...
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Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin based combination therapy with primaquine
... This was the first time that some of the ACT combinations, namely ASMQ, were evaluated for the cure of P. vivax in clinical trial conditions, and thus in combination with daily primaquine (0.5 mg/kg/day for 7-9 ...
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Subsidising artemisinin-based combination therapy in the private retail sector
... also reduce the likelihood of emergence of artemisinin resistance. These studies should ideally use cluster-randomised, interrupted- time-series or plausibility designs (Victora 2004). Future studies should also ...
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Artemisinin-based combination therapy for treating uncomplicated malaria (Review)
... Y Artemisinin-based combination treatments for uncomplicated malaria Malaria is a major cause of illness and death in many of the world’s poorest ...
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Subsidising artemisinin-based combination therapy in the private retail sector
... also reduce the likelihood of emergence of artemisinin resistance. These studies should ideally use cluster-randomised, interrupted- time-series or plausibility designs (Victora 2004). Future studies should also ...
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