artemisinin resistance
Assessment of household ownership of bed nets in areas with and without artemisinin resistance containment measures in Myanmar
... This is the first nationwide study assessing household ownership of, access to, and utilization of bed nets in areas with and without artemisinin resistance contain- ment measures in Myanmar. The study ...
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Optimal treatments for severe malaria and the threat posed by artemisinin resistance
... 1 Optimal treatments for severe malaria and the threat posed by 1 artemisinin resistance 2 Sam Jones, Parasitology Department, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United 3 Kingdom[.] ...
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Status of potential Pf ATP6 molecular markers for artemisinin resistance in Suriname
... This report presents the first data for Suriname on single nucleotide PfATP6 polymorphisms, potentially asso- ciated with artemisinin resistance. Isolates obtained prior to or after adopting Coartem W as ...
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Artemisinin resistance – modelling the potential human and economic costs
... of artemisinin resistance followed by ACT re- sistance, should it occur, will be extremely heterogeneous and dependent on transmission intensity, coverage, partner drug mutation rates, health system ...
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Evaluation of intensified behaviour change communication strategies in an artemisinin resistance setting
... The findings need to be considered in light of some dif- ferences between the communities served by the iBCC and niBCC activities. The populations receiving the intense interventions were living in areas known as Tier 1, ...
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Evaluation of intensified behaviour change communication strategies in an artemisinin resistance setting
... The findings need to be considered in light of some dif- ferences between the communities served by the iBCC and niBCC activities. The populations receiving the intense interventions were living in areas known as Tier 1, ...
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Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh
... If artemisinin resistance spreads westwards from the Mekong region, the CHT may be among the first areas affected of the Indian ...of artemisinin resistance to the African continent ...
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Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia
... into artemisinin resistant (founder subpopulations), sensitive (ancestral population) and admixed subpopu- lations was shown in recent reports ...clinical artemisinin resistance in Cambodia ...
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Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project
... drug resistance is an important cause of mor- bidity and mortality in ...malaria. Artemisinin derivatives are the most potent drugs against multidrug-resistant Plasmodium ...falciparum. ...
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Malaria profiles and challenges in artemisinin resistance containment in Myanmar
... of artemisinin resistance contain- ment projects to prevent national, regional, and global spread of artemisinin drug resistance, there have been few studies that evaluated the coverage of key ...
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Optimal treatments for severe malaria and the threat posed by artemisinin resistance
... We present a highly adaptable methodology for PK/PD mod- eling of treatment of severe malaria that was able to recover key clinical observations (based on circulating parasite numbers), and, with novel metrics, used to ...
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Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin based combination therapy
... Resistance to anti-malarial drugs is one of the major obstacles to effective malaria treatment and control. Due to the worldwide spread of Plasmodium falciparum resistant to chloroquine and sulphadoxine-pyrimetha- ...
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No polymorphisms in K13 propeller gene associated with artemisinin resistance in Plasmodium falciparum isolated from Brazzaville, Republic of Congo
... of resistance are multiple, including self-medication, which does increase drug ...to artemisinin and its derivatives is considered as major risk to public health, which would have a greater impact in ...
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Pfatp6 molecular profile of Plasmodium falciparum isolates in the western Brazilian Amazon
... drug resistance has emerged as one of the biggest challenges confronting the worldwide effort to control ...multi-drug resistance had devastating effects on therapeutic efficacy of former first-line ...
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Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia
... for artemisinin resistance and have reached high frequen- cies in most countries of the ...to artemisinin resistance, countries in the GMS have witnessed more recently the emergence and spread ...
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Prevalence of K13 propeller gene polymorphisms among Plasmodium falciparum parasites isolated from adult symptomatic patients in northern Uganda
... temisinin resistance in a study by Ariey et ...parasite artemisinin resistance has not been ...shown artemisinin agents to be effective in clearing parasites in malaria treatment [25, ...
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Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy
... Currently, artemisinin-resistant ...of artemisinin resistance to other parts of the world is likely, and that vigilant surveillance for arte- misinin resistant parasites is important for controlling ...
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Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012–2013
... with artemisinin re- sistance in Southeast Asia were not detected in other countries in Africa with the exception of the P553L which was detected in one isolate in Mali ...of resistance in Uganda. When ...
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Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa Pun District, Northern Kayin State, Myanmar
... mutations have been found, the distribution of different alleles has been variable. For example, the C580Y poly- morphism is the most common mutation in Cambodia [13, 14], Laos [15, 16] and Vietnam [16], while the F446I ...
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Journal of Applied Pharmaceutical Science
... multidrug resistance 1 gene (Pfmdr 1) in patients showing good therapeutic response (GTR) and artemisinin resistance (AR) following artemether - lumefantrine (AL) treatment of uncomplicated malaria ...
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