atherosclerotic plaque formation
Mathematical modelling of the atherosclerotic plaque formation
... This work is motivated by the design of mathematical models and numerical tools to simulate the first steps in the atherosclerotic plaque formation. The main goal is first to build a mathematical ...
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Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis
... attenuate plaque formation, we used the LDLR -/- mouse model of atherosclerosis ...reverse atherosclerotic plaque formation in mice fed a high-fat (HFD) diet (or chow as ...
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Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
... In this study, we examined lipid peroxidation products, ie, thiobarbituric acid reactive substances (TBARS) and LDL-conjugated diene, formed as a result of oxidative stress generated in a hypercholesterolemic ...
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Original Article Rosuvastatin attenuates the progression of atherosclerotic plaque formation in ApoE mice
... of atherosclerotic plaque ...reduced atherosclerotic plaque areas partially through decreasing the blood lipid ...atherogenic plaque [28, ...
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Hydroalcoholic Extract of Valerian, Blood Factors, and Atherosclerotic Plaque Formation in Male Hypercholesterolemic Rabbits
... Results of this research indicate use of valerian extract together with high cholesterol diets reduces triglycerides, cholesterol, HDL, and LDL. This shows the strong anti-inflammatory and antioxidant properties of this ...
7
Original Article Angiopoietin-like 2 has auxo-action in atherosclerosis by promoting atherosclerotic calcification
... typical atherosclerotic plaque formation in interventional group mice, and Von Kossa staining showed spotty black clumps of aortic calcification under the fibrous cap plaque, while control ...
8
Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study
... Although not yet directly demonstrated, it is possible that liraglutide has beneficial effects on the process of atherosclerotic plaque formation. Pre-clinical data have shown that liraglutide is ...
5
A Case Report for Ischemic Heart Disease Treatment in a 53-Year-Old Man Based on Iranian Integrative Medicine in Bojnurd
... studies in different experimental animals showed that antioxidants reduce low-level lipoprotein oxidation and decrease the rate of atherosclerotic plaque formation [11]. Generally, e[r] ...
9
Modeling fibrous cap formation in atherosclerotic plaque development: stability and oscillatory behavior
... Atherosclerotic plaque formation and growth in arteries are complex processes hemo- dynamically and mechanically. Some plaques, which are build-ups inside your arteries composed of fat, cholesterol, ...
15
Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall
... Our novel SPAM method involves three steps, namely standardisation, permutation, and cluster-enhancement, for the analysis of atherosclerotic plaque formation and tracer distribution in FRI images of ...
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Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide
... in atherosclerotic plaque formation requires NO One day after administration of adenovirus, apoE -/- mice were treated with ...mean plaque and C, MOMA-2 positive areas show that the ...
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Modulation of endothelial cell proliferation and capillary network formation by the ox-LDL component: 1-palmitoyl-2-archidonoyl-sn-glycero-3-phosphocholine (ox-PAPC)
... Abstract Atherosclerotic plaque formation is often asso- ciated with pathological angiogenesis. Modified phospho- lipids, including oxidized lipoproteins such as LDL, are found to induce adhesion of ...
5
Identification and Quantitative Assessment of Different Components of Intracranial Atherosclerotic Plaque by Ex Vivo 3T High Resolution Multicontrast MRI
... Intracranial atherosclerosis is increasingly recognized as an important cause of stroke worldwide. As with carotid atheroscle- rosis, there is increasing recognition that aggressive (dual) antiplatelet therapy may be ...
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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury
... for plaque rupture and ...shows plaque rupture and platelet- and fibrin-rich ...by plaque rupture per se, but by the formation of the platelet-and fibrin-rich occlusive thrombi ...
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Current Concepts of Vascular Injury and Thrombosis in the Pathogenesis of Coronary Atherosclerosis
... to plaque fissuring. Superficial plaque disruption leads to formation of a thrombus that is labile and could be partially dislodged by the laminar flow of ...
8
Prevalence and clinical characteristics of lower limb atherosclerotic lesions in newly diagnosed patients with ketosis-onset diabetes: a cross-sectional study
... erosclerotic plaque and ...limb atherosclerotic plaque was defined as the presence of a focal structure encroaching into the arterial lumen of ...
11
Carotid Plaque Morphology and Ischemic Vascular Brain Disease on MRI
... (ie, plaque size, the presence of intraplaque hemor- rhage, or lipid core) in 80 carotid arteries to be not independently predictive of the severity of WMLs, refuting the large-vessel dis- ease and unstable ...
7
Microbiological Analysis of Periodontal Pocket (Subgingival Plaque) and Coronary Atheromatous Plaque in Atherosclerotic Patients
... In the present study, subgingival plaque samples and atheromatous plaque specimen were examined with the PCR technique using specific primers for periodontal pathogens. The DNA of atleast one of the target ...
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Imaging of the ulcerated carotid atherosclerotic plaque: a review of the literature
... in plaque surface evaluation and identification of irreg- ularities and ulcerations, showing better results than conven- tional US [14, 78 – ...carotid plaque rup- ...
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Simulation of human atherosclerotic femoral plaque tissue: the influence of plaque material model on numerical results
... the plaque tissue to stretch that is far beyond the failure point of the tested ...aortic plaque samples versus the heterogeneous calcified and fibrous tissue behaviour exhibited by the femoral ...
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