Atherosclerotic Plaques
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
... Monocytes participate critically in atherosclerosis. There are 2 major subsets expressing different chemokine receptor patterns: CCR2 + CX3CR1 + Ly-6C hi and CCR2 – CX3CR1 ++ Ly- 6C lo monocytes. Both C-C motif chemokine ...
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Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques
... in atherosclerotic plaques for in vivo imaging, MR is also expressed by some cells in adventitia which causes a non-negligible background signal when using 68 Ga-NOTA-anti-MMR ...human ...
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Noninvasive assessment of the carotid and cerebrovascular atherosclerotic plaques by multidetector CT in type-2 diabetes mellitus patients with transient ischemic attack or stroke
... multiple atherosclerotic plaques, and have higher mortality rates, worse neuro- logic outcome and more severe disability when they suffer a stroke than those without diabetes ...
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High Resolution CT Imaging of Carotid Artery Atherosclerotic Plaques
... MATERIALS AND METHODS: Eight patients with transient ischemic attacks who underwent carotid CTA and “en bloc” endarterectomy were enrolled in a prospective study. An ex vivo micro-CT study of each endarterectomy specimen ...
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Uptake of 68gallium in atherosclerotic plaques in LDLR-/-ApoB100/100 mice
... advanced atherosclerotic plaques [11]. Rup- tured plaques, in particular, commonly contain high quantities of macrophages ...in atherosclerotic plaques, especially in their macro- ...
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The prevalence and distribution of the atherosclerotic plaques in the abdominal aorta and its branches
... sclerotic plaques in abdominal aorta (the preferred branches and parts) is extremely important to predict the clinical results and choose the proper treatment (conservative, medical or surgical) or preventing the ...
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Analysis of the relationship between the inner structure and the magnitude of atherosclerotic plaques
... of atherosclerotic plaques in several groups of coronary artery sections selected on the basis of angiographic ...hard plaques and the lowest of soft plaques was noted in sections with ...
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Tensile and compressive properties of fresh human carotid atherosclerotic plaques
... Tensile and compressive properties of fresh human carotid atherosclerotic plaques Eoghan Maher1, Arthur Creane2, Sherif Sultan3,4, Niamh Hynes3,4, Caitríona Lally2, Daniel J.. Trinity Ce[r] ...
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Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 111In-tilmanocept
... in atherosclerotic plaques of ApoE-KO mice, whereas no signal was detected in the aortas of control ...in atherosclerotic plaques on autoradiography correlating well with Sudan IV-positive ...
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Carotid atherosclerotic plaques standardised uptake values: software challenges and reproducibility
... Although differences between software packages used for oncological PET-CT measurements have been pre- viously explored [15, 16], we hypothesised that explor- ing differences between SUVs of atherosclerotic ...
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Dichotomy in Hedgehog Signaling between Human Healthy Vessel and Atherosclerotic Plaques
... sclerotic plaques. One could thus argue that the amount of HH in plaques is not enough to robustly activate the ...in plaques must constitute inhibition downstream of the primary HH receptor Patched ...
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H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells
... the atherosclerotic plaque could reexpress ...of atherosclerotic plaques, the H19-positive samples were further characterized with respect to collagen, elastin, and actin content as well as with ...
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Artery buckling affects the mechanical stress in atherosclerotic plaques
... of atherosclerotic plaques in coronary arteries leads to thrombus occlusion and heart ...of atherosclerotic plaques in carotid arteries leads to cerebral occlusion and ...investigated. ...
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Macrophage uptake switches on OCT contrast of superparamagnetic nanoparticles for imaging of atherosclerotic plaques
... of macrophages results in NP aggregates that can serve as substantially enlarged scatterers compared to the individual NPs in suspension, thereby increasing light backscattering and attenuation as seen in spectroscopic ...
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Numerical Simulation Of Porosity Effect On Blood Flow Pattern And Atherosclerotic Plaques Temperature
... ABSTRACT: The present work is a numerical simulation of the blood flow around the atherosclerotic plaques in a two dimensional straight stenosis vessel. With assuming the plaque as a homogenous porous ...
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Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques
... Figure 2 The staining signal of liposomal nanoparticles at atherosclerotic plaques is enhanced by globular adiponectin. Aortic sections of apolipoprotein E-deficient and c57Bl6/J wild type mice were ...
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αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice
... demonstrated that atherosclerotic lesions can be imaged with a 99m Tc tracer and a SPECT system, a strategy that confers several advantages. First, SPECT imaging is much more widely available and less expensive ...
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T1 Gadolinium Enhancement of Intracranial Atherosclerotic Plaques Associated with Symptomatic Ischemic Presentations
... The progression and instability of ICAD plaques secondary to neovascularization, IPH, and/or inflammation can present with ei- ther symptomatic ischemic or thromboembolic complications. In extracranial carotid ...
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Association of Lipoprotein Associated Phospholipase A2 with Characteristics of Vulnerable Coronary Atherosclerotic Plaques
... Peripheral blood biomarkers of inflammation have been as- sociated with incident and recurrent cardiac events. Inflam- matory cells, cytokines and other biomolecules are implicat- ed in these processes, and have, ...
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Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles
... of atherosclerotic animals was included as a baseline ...the plaques and the minimum fibrous cap thickness did not differ between animals treated with SPION-DEXA and the control-SPION group (Table ...
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