ATP-binding cassette transporter 2
"We Are Not Hired Help:" The 1968 Statewide Florida Teacher Strike, the Rise of Modern Conservatism, and the Potency of Teacher Power
... different transporter protein families capable of transporting structurally diverse ...the ATP binding cassette (ABC) superfamily [8, ...
181
The COMATOSE ATP-binding cassette transporter is required for full fertility in arabidopsis
... oxidation mutants, only abnormal inflorescence meristem 1 (aim1), which is deficient in a multifunctional protein, has a reported floral/fertility phenotype (Richmond and Bleecker, 1999). However, compared to aim1 ...
39
Atovaquone and quinine anti malarials inhibit ATP binding cassette transporter activity
... (100 mM phenylmethylsulfonyl fluoride, 5 mg/ml aproti- nin, 5 mg/ml leupeptin, 1 mg/ml pepstatin and 1 mg/ml E-64) and shaken at 4°C for 30 min. This lysate was centrifuged 100,000 xg for 30 min at 4°C, after which the ...
8
RPE phagocytic function declines in age related macular degeneration and is rescued by human umbilical tissue derived cells
... ABCA1: ATP-binding cassette transporter 1; AMD: age-related macular degen- eration; ARHGAP9: Rho GTPase activating protein 9; ATCC : American Type Culture Collection; ATP: adenosine ...
15
Expression of Multidrug Resistance ATP Binding Cassette (ABC) Transporters in Canine Mammary Tumors
... 2000 Increased Expression of an ATP-Binding Cassette Superfamily Transporter, Multidrug Resistance Protein 2, in Human Colorectal Carcinomas.. and Gerlach, J.H.[r] ...
9
Multiple common and rare variants of ABCG2 cause gout
... in atP-binding cassette transporter subfamily g member 2/breast cancer resistance protein (ABCG2/BCRP), including rs72552713 (Q126X) and rs2231142 ...
8
Pulmonary Nodules in a Newborn With ATP-Binding Cassette Transporter A3 (ABCA3) Mutations
... Electron-microscopy image, which shows large, partially intact, residual lamellar bodies present in type II cells of the lung (arrow). Tissue was fixed in 2% glutaraldehyde and 2% paraformaldehyde in 0.1 M ...
7
Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism
... ABCA1: ATP-binding cassette class A transporter; CKD: Chronic kidney disease; CVD: CARDIOVASCULAR disease; ERK1/2: Extracellular signal regulated protein kinases 1/2; ESRD: End ...
10
Copy number variations of the ATP binding cassette transporter ABCC6 gene and its pseudogenes
... μL Binding Buffer (Qiagen), 2 μL streptavidin sepharose high-performance beads (GE Healthcare, Little Chalfont, United Kingdom) and 18 μL water and stirred for 5– 10 min at 1400 rpm on a ...for 2 min ...
6
The COMATOSE ATP-binding cassette transporter is required for full fertility in Arabidopsis
... agreement with the phenotype reported for the pxa1 allele (Zolman et al., 2001) and the assertion that b -oxidation of fatty acids does not play a prominent role in vegetative growth of the unstressed plant, although it ...
15
The ATP-binding cassette (ABC) transporter OsABCG3 is essential for pollen development in rice
... Sporopollenin is complex biopolymers mainly consist- ing of polyhydroxylated aliphatic compounds and phe- nolics conjugated by ether and ester bonds (Jiang et al. 2013; Shi et al. 2015; Zhang et al. 2016). Genetic ap- ...
15
Novel analytical methods to interpret large sequencing data from small sample sizes
... ABCB1: ATP-binding cassette subfamily B member 1; ABCG2: ATP-binding cassette subfamily G member 2; AltAF: Alternate allele frequency; BCR-ABL1: Breakpoint cluster region- ...
11
Human ATP-binding cassette (ABC) transporter family
... The human genome carries 49 ABC genes, arranged in seven subfamilies, designated A to G (Figure 1 and Table 1). This diverse transporter family has members that play pivotal roles in many cellular processes. For ...
10
The role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance
... Cancer is the second most important factor causing death in developing countries (1) and a main health concern worldwide (2). Leukemia is one of the commonly reported cancers (9%) (3) including34% of all cases ...
9
Molecular chess? Hallmarks of anti cancer drug resistance
... The ATP-binding cassette (ABC) superfamily of proteins includes a number of membrane proteins able to transport a wide diversity of ...ABC transporter molecules [10], many of which can pump ...
8
ABC transporter research: going strong 40 years on
... The ATP-binding cassette (ABC) transporter field emerged from studies on nutrient uptake in bacteria in the 1970’s with the biochemical characterization of substrate-binding protein ...
9
An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein
... mensal in poultry, cattle and swine (Harris et al ., 1986; Kazwala et al ., 1990). The characteristics of the disease caused by C. jejuni in humans are diarrhoea, cramps, abdominal pains and fever, unfolding 2–5 ...
14
Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors
... (Table 2) ...the ATP-binding cassette transporter A- 1 (ABCA1), ABCA7, apolipoprotein C2 (APOC2), APOC4, and phospholipid transfer protein (PLTP); the complement pathway VTN gene; and ...
20
ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches
... Figure 3 Schematic overview of the roles of ABCG2 in hyperuricemia and gout. (A) The ABCG2 transporter is highly expressed in the gut, where it regulates ATP-dependent uric acid excretion. The 141K ABCG2 ...
14
Contributions of Aspergillus fumigatus ATP-Binding Cassette Transporter Proteins to Drug Resistance and Virulence
... We also provide evidence that the promoters of both abcA and abcB can drive azole-inducible gene expression. Previous microar- ray experiments indicated that a number of different azole-induc- ible genes are present in ...
10