Augmentation Treatments with Second-generation Antipsychotics to
Second-generation antipsychotics
... was prescribed for the patient for the six months before the index date. The mean±SD number of days that pa- tients received a single second-gener- ation antipsychotic was 121±60.9 days for patients in the case ...
8
Cost-Effectiveness of Second-Generation Antipsychotics for the Treatment of Schizophrenia
... of antipsychotics were assessed by considering a response rate, rates of no or tolerable side effects, patients’ decision to continue using a medication, and relapse ...
10
Second-generation antipsychotics for obsessive compulsive disorder (Review)
... of anxiety and depression. The latter data were, however, possibly skewed, limiting interpretation. There was no difference in terms of leaving the trial early for any reason (risperidone 14%, placebo 18%), suggesting ...
75
Second generation antipsychotics in the long-term treatment of schizophrenia
... The cause of death in schizophrenic patients is suicide in about 10%. Clozapine is regarded as the prototype of second-generation antipsychotic agents. The clinical experiences, several studies and in ...
20
Effectiveness of second generation antipsychotics: A systematic review of randomized trials
... tional antipsychotics which could confound comparisons between the SGAs ...with antipsychotics may deliver valuable information in the decision making about choosing an antipsychotic ...
14
Clinically Relevant Interactions between Newer Antidepressants and Second-Generation Antipsychotics
... the second trial, administration of duloxetine, 60 mg/day for up to 6 weeks, to 20 outpatients stabilized on clozapine (n=6), olanzapine (n=8) or risperidone (n=7), did not modify the plasma concentrations of ...
55
Do New Prescription Drugs Pay for Themselves?: The Case of Second-Generation Antipsychotics
... “second-generation” antipsychotics are substantially more expensive than the drug treatments that preceded them and were numbers one, two, and four, respectively, among all prescription drugs ...
45
Metabolic consequences of second-generation antipsychotics in youth: appropriate monitoring and clinical management
... Summary The present review article has focused mainly on monitoring and intervention of metabolic side effects of SGAs, given these appear to be the most common and problematic. The mechanism of metabolic side effects, ...
12
Second-Generation Antipsychotics and Neuroleptic Malignant Syndrome: Systematic Review and Case Report Analysis
... Study Appraisal and Synthesis Methods A standardized method for data extraction and coding was developed for the analysis of eligible case reports. Results Six primary studies and 186 individual cases of NMS induced by ...
18
Off-Label Use of Second Generation Antipsychotics in Anxiety Disorders and Obsessive Compulsive Disorder
... for augmentation of antidepressants treatment in patients with social phobia who appear to be resistant to SSRIs, MAOIs, anxio- lytics, and when cognitive-behavioral therapy is not possible or available (Praško ...
12
Effectiveness of second generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone
... Limitations Some limitations to the study need to be discussed. The randomization was open to both the treating clinician and the patient. Systematic utilization differences among the SGAs before the start of the study ...
13
Second-generation long-acting injectable antipsychotics in schizophrenia: patient functioning and quality of life
... injectable antipsychotics (LAIs) were developed to make treatment easier, improve adherence, and/or signal the clinician when nonadherence ...occurs. Second- generation antipsychotic LAIs (SGA-LAIs) ...
13
Patterns of initiation of second generation antipsychotics for bipolar disorder: a month by month analysis of provider behavior
... psychiatric hospitalization, recent psychotic features, or recent sleep disorder diagnosis); this is consistent with our finding that those who received an SGA also—at some time during the study period—received another ...
10
Use of second-generation antipsychotics in the acute inpatient management of schizophrenia in the Middle East
... their antipsychotics at any given time, and often suffer from exacerbations and relapses that require ...of antipsychotics published in The Maudsley Prescribing Guidelines in Psy- ...concurrent ...
10
Comparative study of treatment continuation using second-generation antipsychotics in patients with schizophrenia or schizoaffective disorder
... Materials and methods Study design The second-generation antipsychotics investigated were aripiprazole, blonanserin, olanzapine, perospirone, quetia- pine, and risperidone. These were the agents ...
5
Continuing Professional Development Program on Second-Generation Antipsychotics for Psychiatric-Mental Health Staff Nurses
... typical antipsychotics and atypical antipsychotics in patients diagnosed with schizophrenia, schizoaffective disorders, and with a history of physical assault in a state ...
62
Update on the safety of second generation antipsychotics in youths: a call for collaboration among paediatricians and child psychiatrists
... The dopamine blockade on the anterior lobe of the pitu- itary gland due to SGAs is often associated with hyper- prolactinemia. Raises in prolactin (PRL) levels may cause gynecomastia, galactorrhea, irregular menses, and ...
11
Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review
... of antipsychotics is a complex domain, which can be influenced by baseline cognitive ability, 56 plus anxiety, mood, positive, negative, and residual symptoms in patients with ...of antipsychotics on ...
21
Comparative effectiveness of second generation long-acting injectable antipsychotics based on nationwide database research in Hungary
... Our study has its own limitations. A potential disadvantage of real-world studies compared to randomized clinical trials is the lack of randomization of patients, thus the potential lack of comparability between ...
14
Comparison of Olanzapine versus Other Second-Generation Antipsychotics in the Improvement of Insight and Medication Discontinuation Rate in Schizophrenia
... schizophrenia. Second, due to the nature of observational study, the lack of random assignment and some bias factors such as treating physicians’ individual prescribing preference, drug prices, and treatment ...
10