Autoimmune and inflammatory conditions
PD-L1– and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease
... To determine the functional effects of liposome-induced OVA-specific pTregs, we adoptively trans- ferred a cohort of DO11.10 T cells and treated recipients with s.c. OVA/calcitriol liposomes, before trans- ferring a ...
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Smoking under hypoxic conditions: a potent environmental risk factor for inflammatory and autoimmune diseases
... normoxic conditions, PHDs hydroxylate and inhibit IKK activity, which does not occur under hypoxic conditions, enabling IKK-mediated phosphoryl- ation and promoting degradation of IκB and thus acti- vating ...
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Autoimmune / inflammatory syndrome induced by adjuvants (ASIA) – variety of symptoms
... The variety of symptoms and conditions that may develop after implantation can be illustrated by several clinical cases, which will be presented below. An interesting case of ASIA syndrome occurred in a ...
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Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
... of autoimmune arthritis, Th17 cells are the dominant initiators of in ...under conditions that mimic the disease site, namely low TGF β and high IL-12 levels, whereas Th1 cells cannot convert to ...
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Role of obesity and pro-inflammatory leptin in autoimmune thyroiditis independent on hypothyroidism
... on autoimmune disease independent on ...on autoimmune thyroiditis through the role of adipocyte pro- inflammatory leptin, indicating a high risk for obese persons to develop thyroid ...
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Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases
... Takayasu arteritis UMIN000007845 Current clinical trials of tocilizumab in the USA, EU and Japan are listed. GVHD: graft-versus-host disease; ANCA: anti-neutrophil cytoplasmic antibody. On the basis of the pathologic ...
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Conventional and Nano-Based Therapy against Chronic Inflammatory Autoimmune Diseases
... in autoimmune disease triggers the inflammatory response resulting in recursion of immunologically competent cells to aggravate further the situation resulting in the intensification of the ...
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Astrocytes differentially respond to inflammatory autoimmune insults and imbalances of neural activity
... general autoimmune insult in ...physiological conditions astrocytic endfeet play a major role in regulating the flow of cerebrospinal fluid and solutes into the brain parenchyma, and that AQP4 is important ...
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Autoimmune conditions and hairy cell leukemia: an exploratory case-control study
... immune conditions has been linked to lymphoma, a recent study has suggested that the severity of the con- dition, not its treatment, is responsible for the added risk ...certain autoimmune conditions ...
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The Lifetime Risk of Adult-Onset Rheumatoid Arthritis and Other Inflammatory Autoimmune Rheumatic Diseases
... of inflammatory autoimmune rheumatic disease development is substan- tial at 1 in 12 for women and 1 in 20 for ...these conditions and have impor- tant implications regarding disease awareness ...
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Autoimmune conditions and comorbid depression in pregnancy: examining the risk of preterm birth and preeclampsia.
... both autoimmune disease and depression on pregnancy ...the autoimmune condition contributes to the high level of depression, as depression itself is associated with an increase in inflammatory ...
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Transforming growth factor β induced regulatory T cells referee inflammatory and autoimmune diseases
... TGF-ββ-converted Treg control immune responses in vivo On the basis of this understanding of the novel mechanism underlying conversion of CD4 + CD25 – T cells into phenotypic and functional CD4 + CD25 + Treg, the ...
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Airway Autoimmune Inflammatory Response (AAIR) Syndrome: An Asthma-Autoimmune Overlap Disorder?
... CoNCLUsIoNs We describe 3 patients who collectively may represent a novel disorder that we term “airway autoimmune inflammatory response syndrome.” We advocate both rheumatologic and bronchoscopic ...
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The Role of HMGB1 in the Pathogenesis of Inflammatory and Autoimmune Diseases
... the autoimmune disease systemic lupus erythematosus (SLE), since genetic abnormalities such as defi- ciency of complement or other cellular or humoral clearance system can lead to au- toantibody production in ...
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Vaccination in chronic autoimmune and inflammatory rheumatic diseases
... with autoimmune infl ammatory rheumatic dis- eases developed by European League Against Rheuma- tism (EULAR) will help rheumatologists in making a decision about vaccinating their ...
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Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis
... C5a-mediated inflammatory responses in auto- immune ...exacerbated inflammatory arthritis in a mouse model of RA, and cleavage of C5a by CPB suppressed the ability of C5a to recruit immune cells in ...
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Type I interferon in organ targeted autoimmune and inflammatory diseases
... In that view, the high level expression of type I interferon and interferon-inducible genes would refl ect an active but insuffi cient eff ort of the innate immune system to control a more primary infl ammatory process. With ...
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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses
... complex I, complex III and complex IV activity is grossly reduced in normal appearing gray matter and in normal tissue within the motor cortex in patients suf- fering from this illness [53,54]. There is also direct evi- ...
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← Return to Article Details Natural Support for Autoimmune and Inflammatory Disease
... an inflammatory response attempt to protect themselves by secreting anti-inflammatory prostaglandins, antioxidants, anti-chemotactic chemicals, and ...The inflammatory response subsides; suppressor T ...
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Autoimmune inflammatory disorders, systemic corticosteroids and pneumocystis pneumonia: A strategy for prevention
... two opposing trends have resulted in HIV negative patients constituting an ever increasing proportion of the total number of cases of PCP. Attempts have been made to characterise the incidence of PCP amongst patients ...
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