Autoimmune Disease
Immune ablation and stem cell therapy in autoimmune disease Clinical experience
... versus-host disease, which are not often seen in autologous HSC ...for autoimmune disease [5 • ] suggest a TRM of approximately 8–9%, perhaps relating to a sicker population of patients with ...
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Antigen-based immunotherapy for autoimmune disease: current status
... Abstract: Autoimmune diseases are common chronic disorders that not only have a major impact on the quality of life but are also potentially ...for autoimmune disease would specifically target ...
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MAP4K3/GLK in autoimmune disease, cancer and aging
... in autoimmune disease ...from autoimmune disease patients; the GLK-overexpressing T cell population is correlated with disease severity of ...of autoimmune disease by GLK ...
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T cell metabolism in autoimmune disease
... rheumatic disease, studies on pathogenic pathways in the autoimmune disease multiple sclerosis have been highly informative in deciphering immune ab- normalities that lead to immune-driven tissue ...
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B cell depletion in autoimmune disease
... The exact mechanism of action of B cell depletion in autoimmune disease is still unclear. The clinical state improves over a number of months despite almost immedi- ate B cell depletion [3]. Furthermore, ...
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A Multiplex Autoantibody Panel for Early Detection of Autoimmune Disease Activity
... The most relevant consequence of performing a multiplex ANA + ENA panel is its ability to predict autoimmune disease by detecting early autoantibodies. This study confirms that anti-ENA bodies could be ...
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← Return to Article Details Thyroid Autoimmune Disease
... of autoimmune thyroid disease has not been elucidated, there are several factors that have been associated with the ...For autoimmune disease, vitamin D supplementation is recommended as ...
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Synergy between a plasminogen cascade and MMP 9 in autoimmune disease
... Extracellular proteolysis by the plasminogen/plasmin (Plg/plasmin) system and MMPs is required for tissue injury in autoimmune and inflammatory diseases. We demonstrate that a Plg cascade synergizes with MMP-9/ ...
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Random pharmacokinetic profiles of EC-MPS in children with autoimmune disease
... with autoimmune disease without a concomitant calci- neurin ...mune disease and whether trough level monitoring is feasible to study exposure in these ...
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MicroRNAs in autoimmune disease
... inflammatory autoimmune disease characterized by auto- antibodies against various self-antigens and damage to major organ ...SLE disease activity index (SLEDAI) and eight ...
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Helminth immunomodulation in autoimmune disease
... of autoimmune disease, helminths have become of heightened scientific interest due to their ability to activate immunoregulatory circuits and control ...celiac disease, UC, CD, MS, RA, and psoriasis ...
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PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease
... Given the causative role of Th1 and Th17 cells in auto- immune diseases such as MS [2-4], we proposed that through restriction of Th1 and Th17 cell differentiation, PDLIM2 is involved in autoimmune disease ...
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Autoantibody profiling for the study and treatment of autoimmune disease
... from patients with autoimmune disease. They provide a powerful tool to characterize autoreactive B-cell responses in diseases including rheumatoid arthritis, multiple sclerosis, autoimmune diabetes, ...
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Current perspectives on the role of IL-17 in autoimmune disease
... of autoimmune disorders has dramati- cally changed the prognosis of these ...of autoimmune diseases is ...that autoimmune diseases are categorized as Th1- or Th2-mediated ...Crohn’s disease ...
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Familial Aggregation of Autoimmune Disease in Juvenile Dermatomyositis
... liac disease and psoriasis were found at significantly lower rates in JDM fam- ilies than would be expected in the gen- eral ...comitant autoimmune conditions lim- its our ability to make statistical ...
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July 30, Probable Link Evaluation of Autoimmune Disease
... associations to occur as a result of chance or bias, and plausibility based on experiments in laboratory animals. The relative risk (RR – which can include specific measures such as rate ratios, odds ratios, hazards ...
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Cutaneous tolerance induction : a possible strategy for the treatment of autoimmune disease
... 5.2.8 Generation of transferable suppression in 3dnTx mice 092 5.2.9 Generation of antigen specific suppressor cells in 3dnTx mice 092 5.2.10 DMBA/TNCB treatment reduced contact sensitiv[r] ...
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B cells as a therapeutic target in autoimmune disease
... The discovery of autoantibodies in chronic inflammatory diseases initiated an era of clinical investigation and estab- lished the foundation of modern clinical immunology. The original descriptions of antinuclear ...
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Vogt-Koyanagi-Harada disease: review of a rare autoimmune disease targeting antigens of melanocytes
... Changes in FA during the acute uveitic stage are charac- teristic [62, 97] and can help differentiate VKHD from other conditions (Fig. 2). Initially, with active inflamma- tion, FA reveals a delay in choroidal perfusion, ...
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Amplification of autoimmune disease by infection
... Circumstantial evidence for the hypothesis In summary, it is possible that both herpesviruses and Chlamydiae gain access to sites of chronic tissue inflammation through a Trojan horse mechanism, because the influx of ...
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