Autoimmune Diseases (Multiple Sclerosis
Current perspectives on the role of IL-17 in autoimmune disease
... of autoimmune disorders has dramati- cally changed the prognosis of these ...of autoimmune diseases is ...that autoimmune diseases are categorized as Th1- or Th2-mediated ...and ...
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Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis
... in urine, could be sufficient to slow or even prevent the onset or appearance of more severe EAE symptoms. The above discussion of the therapeutic effects of CHEC-9 assumes that the peptide's effects are due to enzyme ...
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Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma
... of Diseases codes used have been described previously ...lateral sclerosis, autoimmune hemolytic anemia, celiac disease, chorea minor, type 1 diabetes, discoid lupus, localized scleroderma, lupoid ...
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Autoimmune Comorbidities Are Associated with Brain Injury in Multiple Sclerosis
... mediated diseases driven by Th1 and Th2 subsets suggests a com- mon aetiology: a population-based study using computerized gen- eral practice ...with multiple sclerosis in a cohort of 658 consecutive ...
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T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
... Clearly, much of the focus in recent literature has been on the relative role of Th17 and Th1 cells in EAE and MS; however, as reviewed above this question is not clear-cut and still far from being resolved. While EAE ...
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Familial risk of systemic sclerosis and co aggregation of autoimmune diseases in affected families
... other autoimmune diseases The case definition for SSc was a person with a catastrophic illness certificate for SSc (International Classification of Diseases, Ninth Revision (ICD-9) code ...other ...
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Latent Tuberculosis Infection in Patients with Multiple Sclerosis
... Multiple Sclerosis (MS) is a chronic and autoimmune neurological disease caused by lymphocytic infiltration. Its prevalence worldwide is 22.2 million cases of MS. There is a relation between TB and ...
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Familial risk of Sjögren's syndrome and co aggregation of autoimmune diseases in affected families: a nationwide population study
... other autoimmune diseases in affected ...systemic sclerosis, idiopathic inflammatory myopathy, type 1 diabetes mellitus, multiple scle- rosis, myasthenia gravis, inflammatory bowel ...
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The MRZ reaction in primary progressive multiple sclerosis
... other autoimmune inflammatory neurological diseases (OIND) such as neuromyelitis optica (NMO), paraneo- plastic neurological syndromes (PND), neurosarcoido- sis (NS), acute disseminated encephalomyelitis ...
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Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ?
... these diseases with autoimmune encephalomy- elitis or neuritis in rodents, it is likely that these disorders are mediated by CD4 + autoreactive T-cells ...brain autoimmune disease and about immune ...
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The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort
... CNS autoimmune diseases [11]. In this regard, autoimmune encephalitis (AIE) is a well char- acterized example of CNS autoimmunity suitable for fur- ther investigation of the specificity of ...
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Reactive oxygen species in organ-specific autoimmunity
... the autoimmune response but also in its amplification and spreading to novel epitopes, through the unmasking of cryptic ...specific autoimmune diseases (Hashimoto thy- roiditis, inflammatory bowel ...
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Deciphering the role of DNA methylation in multiple sclerosis: emerging issues
... The majority of attempts to identify changes in DNA methylation across the genome can be distinguished into two approaches: candidate-gene approach, where specific genetic loci are selected and examined for differences ...
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Cannabis and Autoimmunity - The Neurologic Perspective: A Brief Review
... Notably, a new large multi centered blinded study was recently published, in which 489 MS patients participated and received either oral dronabinol (THC) or placebo. The study failed to prove the beneficial outcome of ...
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Negative results associated with medicines and quality of life in multiple sclerosis
... 2017). Multiple sclerosis (MS) is a chronic, autoimmune disease that affects the central nervous system (CNS) and is considered one of the non-traumatic neurological conditions that most causes ...
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... FIGURE 4. Induction and inhibition of autophagy affect apoptosis pathway in experimental autoimmune encephalomyelitis (EAE) mice. (A) Terminal-deoxynucleotidyl-transferase-mediated deoxyuridine triphosphate-biotin ...
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Nav1.6 promotes inflammation and neuronal degeneration in a mouse model of multiple sclerosis
... To quantify and visualize RGCs, the whole-mount ret- inas were incubated for 6 days at 4 °C with primary anti- body against the mouse RNA-binding protein with multiple splicing (RBPMS; 1:1000 dilution, guinea pig ...
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Calnexin is necessary for T cell transmigration into the central nervous system
... the Multiple Sclerosis Society Tissue Bank, funded by the Multiple Sclerosis Society of Great Britain and Northern Ireland, registered char- ity ...the Multiple Sclerosis Society ...
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Neuroprotective therapies for multiple sclerosis and other demyelinating diseases
... [4, 28, 29]. The CNS consumes 20 % of the overall oxygen and energy of the body and neurons require the support of astrocytes for maintaining their metabolic activity [6]. Neurons use lactate as a substrate for the Krebs ...
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Mixed connective tissue disease: state of the art on clinical practice guidelines
... different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ...
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