autophagic vacuoles
Infectious Bursal Disease Virus Subverts Autophagic Vacuoles To Promote Viral Maturation and Release
... not shown). A previous study showed that rapamycin does not induce obvious au- tophagy in DF-1 cells as it does in mammalian cells (32). Cells were starved of amino acids, a condition also known to induce autophagy (40). ...
18
Induction of apoptosis and autophagy via mitochondria- and PI3K/Akt/mTOR-mediated pathways by E. adenophorum in hepatocytes of saanen goat
... DAPI, MDC and LC3 immunostaining using fluorescent antibodies to LC3-II were conducteded to confirm autophagy induction by E. adenophorum. Also, different sections of livers were measured by TEM to detect apoptosis and ...
12
Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B
... MDC-positive autophagic vacuoles in the experimental groups compared to the control group (Figure ...abundant autophagic vacuoles sequestered in the cytoplasm and organelles, such as ...
10
Original Article The fusion of autophagosome with lysosome is impaired in L-arginine-induced acute pancreatitis
... of autophagic vacuoles and massive acinar cell destruction (presumably due to massive necrosis) were first observed in human acute pancreatitis speci- mens ...
7
Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy
... The intracellular localization of Apg proteins appears close to the autophagic vacuoles (38, 53). To determine if HCV replicase proteins (for example, NS4) colocalized with the au- tophagic marker protein ...
10
Activation of mTOR: a culprit of Alzheimer’s disease?
... Abbreviations: Akt, protein kinase B; AMPK, AMP-activated protein kinase; APP, amyloid precursor protein; Avs, autophagic vacuoles; GSK-3, glycogen synthase kinase 3; iGF-1, insulin-li[r] ...
16
The emerging role of autophagy in Parkinson's disease
... of autophagic vacuoles is evident in the brains of PD patients, in contrast to the rare detection of autophago- somes in normal brain, due to the rapid clearance of these vesicles in the central nervous ...
6
Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats
... and autophagic vacuoles (AVs) were examined by autophagic marker (LC3 and p62) expression and transmission electron microscopy (TEM) image, ...
15
Minocycline-associated rimmed vacuolar myopathy in a patient with rheumatoid arthritis
... The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle ...by autophagic vacuoles with unique ...
6
Structural, Biochemical, and Cell Biological Characterization of Rab7 Mutants That Cause Peripheral Neuropathy
... Maintenance of cellular homeostasis requires regulation of the biogenesis and trafficking of diverse membranous subcellular organelles and vesicles. Membranous compartments such as the endoplasmic reticulum (ER), the ...
171
Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease
... Apart from mutations in genes that directly encode for lysosomal components, direct and indirect roles have been proposed for numerous other PD-related mutations in the process of autophagy. A rare form of autosomal ...
18
The Physiology Of Contractile Vacuoles
... On these assumptions the rate of output required to account for a given rate of aody-volume decrease can be calculated as follows: I At any instant R0 = Ri + Rv and Rt = kSP-p II, where [r] ...
17
The Physiology Of Contractile Vacuoles
... It was found that cyanide could for a short time completely inhibit the actions of the contractile vacuoles of fresh-water Peritricha; therefore experiments were also carried out with so[r] ...
9
Host/pathogen interactions Subversion of the mammalian cell cytoskeleton by invasive bacteria
... membrane-bound vacuoles ( Yersinia and Salmonella ), or rapidly lyse such vacuoles and move within the cytoplasm by a process involving continuous polymerization of host actin at the posterior end of the ...
6
AMPylation Is Critical for Rab1 Localization to Vacuoles Containing Legionella pneumophila
... localization to the LCV and that other Rab1-deactivating factors, such as host GAPs, may be dominant over LepB under these con- ditions. To determine if AMPylation protected Rab1 from deacti- vation by LepB, a Legionella ...
11
The Physiology of Contractile Vacuoles
... And in marine forms, if the cell membrane is relatively impermeable to salts, the same argument can be applied, namely, that since no more salts can leave the organism than enter it, the[r] ...
18
Tonoplast intrinsic proteins and vacuolar identity
... multiple vacuoles may be present within the same cell ...multiple vacuoles in plant cells, with protein storage vacuoles (PSV) having alpha-TIP (TIP3;1) and delta-TIP (TIP2;1) on their tonoplast, and ...
16
Ultrastructure of vacuoles in root tips
... Cytoplasm of an outer root cap cell showing the form of golgi apparatus, in its vicinity occur several round electron-dense bodies apparently derived from the ends of cisternae; at this [r] ...
276
<p>Bacteria Exploit Autophagy For Their Own Benefit</p>
... marinum. Autophagic machinery was recruited at the distal pole of ejecting bacteria, disruption of autophagy causes the host cells to become leaky and die during ejection suggest that autophagy maintains the ...
11
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
... Lysosomal/autophagolysosomal membrane permeabilization (LMP) was also assessed by acridine orange staining and quantifying the red fluorescence (when it is present in acidic vacuoles such as lysosomes and ...
18