autophagy-related
Original Article Expression of autophagy-related proteins in phyllodes tumor
... examine autophagy activity in the PTs, we performed immunohistochemistry of autophagy-related proteins (Figure ...assess autophagy activities were as follows: beclin-1 as a participant in ...
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Autophagy Related Protein ATG18 Regulates Apicoplast Biogenesis in Apicomplexan Parasites
... of autophagy, which is dependent on autophagy-related proteins (ATGs), is one of the major targets of 3=-PIPs in yeast and ...identified autophagy-related protein ATG18 as an ef- fector ...
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Identification and characterization of the autophagy related genes Atg12 and Atg5 in hydra
... described autophagy and its role in physiology in ...regulate autophagy induction. For instance, silencing of Kazal-1 induces autophagy in gland cells and digestive (endodermal myoepithelial cells) ...
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Autophagy Related Protein ATG8 Has a Noncanonical Function for Apicoplast Inheritance in Toxoplasma gondii
... ABSTRACT Autophagy is a catabolic process widely conserved among eukaryotes that permits the rapid degradation of un- wanted proteins and organelles through the lysosomal ...of autophagy-related ...
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Original Article Autophagy-related genes affect drug resistance of mycobacteria by regulating autophagy
... [1]. Autophagy refers to the process of degrading intracellular damaged or- ganelles or foreign bodies using autophagoso- mes, lysosomes, and other autophagy-related organelles in the body under the ...
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MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells
... hypoxia. Autophagy plays a protective role in cancer cells under ...reduced autophagy remain poorly understood in ...hypoxia-induced autophagy in GBM ...hypoxia-induced autophagy, whereas ...
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Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis
... clinical. Autophagy is an important cell biological mechanism in maintaining the homeostasis of tissues and cells, resisting the process of ...whether autophagy could resist intraocular fibrosis and prevent ...
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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
... out autophagy, and that this promotes their ...essential autophagy genes microtubule- associated protein 1 light chain 3b (MAP1LC3B) and autophagy-related gene 5 (ATG5) through the ...
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The Role of Autophagy in Cell Survival and Cell Death
... cases autophagy can also promote the survival of cancer cells once tumours have ...of autophagy to promote cell survival under conditions of poor nutrient supply, as often faced by solid tumours and ...
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Cullin-RING ligases in regulation of autophagy
... Beclin-1-regulated autophagy; AMPK: AMP-activated protein kinase; ATF4: activating transcription factor 4; ATG: autophagy related gene; Bcl-2: B-cell lymphoma 2; BTB: bric-a-brac, tramtrack, ...
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A balancing act for autophagin
... ever, autophagy can also be induced by phys- iologic and pathologic conditions, such as nutrient starvation and infection by patho- gens (4, ...of autophagy in surviving neonatal starvation ...stopped, ...
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<p>The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress</p>
... and autophagy by ER ...and autophagy related proteins expression following treating with the ER stress inhibitor 4- PBA and autophagy inhibitor ...
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Clinicopathologic characterization and abnormal autophagy of CSF1R related leukoencephalopathy
... the autophagy progress. Since LC3 is the most widely moni- tored autophagy-related protein, and LC3-II is more stable and more closely related to autophagosomes than LC3-I, the consensus on ...
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Fluid Shear Stress Promotes Autophagy in Hepatocellular Carcinoma Cells
... shear stress (ranged from 10min to 2h) [13, 42], which are faster than biochemical factors [43, 44]. Our studies determined the effects of FSS on the expression of ATG5, ATG7, Beclin-1 and P62 at mRNA and protein levels, ...
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Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
... : Autophagy and beclin 1 regulator 1; APC: Allophycocyanin; APOL6 : Apolipoprotein L6; ATG14 : Autophagy related 14; BCL2A1 : BCL2 related protein A1; BDCA: Blood dendritic cell antigen; BECN1 ...
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Enhanced Autophagy in Polycystic Kidneys of AQP11 Null Mice
... that autophagy may play a role in the cyst formation and examined autophagy activity before and after cyst development in AQP11(-/-) ...other autophagy-related genes in AQP11(-/-) ...enhanced ...
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Identification and validation of an individualized autophagy-clinical prognostic index in gastric cancer patients
... basic autophagy in normal cells can avoid the accumula- tion of some DNA mutation molecules and organelles, and prevent cell transformation ...basal autophagy in tumor cells is conducive to the cancer cells ...
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Original Article Molecular mechanism of NF-κB signal pathway in autophagy of retinoblastoma cell line HXO-RB44
... cell autophagy is closely cor- related with eye disease especially ...cell autophagy disorder in the patho- genesis of RB and clinical ...measured autophagy condition of cells, as demonstrated ...
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An Atlas of the Genetic Variations Linking Dysregulation of Autophagy to Human Diseases: The Missing Environmental Link
... 191. Martin LJ, Gupta J, Jyothula SSSK, Butsch Kovacic M, Biagini Myers JM, Patterson TL, Ericksen MB, He H, Gibson AM, Baye TM, et al. Functional Variant in the Autophagy- Related 5 Gene Promotor is ...
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Autophagy and apoptosis-related genes in chronic liver disease and hepatocellular carcinoma
... Beclin 1 is one of the main autophagocytic agents, a regula- tor gene that bridges autophagy, apoptosis and differenti- ation. In our study, Beclin 1 mRNA expression was constitutive of all the tissues examined ...
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