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avidity index

Precision and Accuracy of a Procedure for Detecting Recent Human Immunodeficiency Virus Infections by Calculating the Antibody Avidity Index by an Automated Immunoassay Based Method

Precision and Accuracy of a Procedure for Detecting Recent Human Immunodeficiency Virus Infections by Calculating the Antibody Avidity Index by an Automated Immunoassay Based Method

... the avidity index (AI) of anti-HIV antibodies has been recently proposed (7, ...low avidity for the antigen. In fact, it is well known that antibody avidity increases progressively with time ...

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Urea dilution of serum for reproducible anti HSV1 IgG avidity index

Urea dilution of serum for reproducible anti HSV1 IgG avidity index

... The Urea solution (150 μl) was allowed to soak the wells containing ag-bound anti-HSV1 IgG for 8 min, as re- ported earlier [6]. By dividing the values for Absorbance (Urea/no Urea) for doublets run with and without the ...

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European Multicenter Study of the LIAISON Automated Diagnostic System for Determination of Toxoplasma gondii Specific Immunoglobulin G (IgG) and IgM and the IgG Avidity Index

European Multicenter Study of the LIAISON Automated Diagnostic System for Determination of Toxoplasma gondii Specific Immunoglobulin G (IgG) and IgM and the IgG Avidity Index

... IgG avidity index is not standardized between labora- tories, and no external quality assurance program includes the Toxoplasma-specific IgG avidity ...the index, but mod- eling has shown wide ...

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Significance of IgG-Avidity in Antenatal Rubella Diagnosis.

Significance of IgG-Avidity in Antenatal Rubella Diagnosis.

... Secondary Rubella Virus Infection (i.e. reinfection) It was observed that two of the screened pregnant women had borderline Rubella virus-specific IgM antibodies in their sera. However, one of these subjects also tested ...

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Avidity of anti malarial antibodies inversely related to transmission intensity at three sites in Uganda

Avidity of anti malarial antibodies inversely related to transmission intensity at three sites in Uganda

... in avidity index observed in this study on acquisition of clinical or anti-parasite immu- nity is not ...antibody avidity is theoretically important in the function of an antibody response [45], ...

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Simplified Assay for Measuring Toxoplasma gondii Immunoglobulin G Avidity

Simplified Assay for Measuring Toxoplasma gondii Immunoglobulin G Avidity

... (IgG) avidity enzyme-linked immunosorbent assay (ELISA) was developed that combines the accuracy of assays based on end point titers and the relative ease of assays based on optical density ...assay’s ...

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National Prevalence Estimates for Cytomegalovirus IgM and IgG Avidity and Association between High IgM Antibody Titer and Low IgG Avidity

National Prevalence Estimates for Cytomegalovirus IgM and IgG Avidity and Association between High IgM Antibody Titer and Low IgG Avidity

... antibody avidity, two CMV-specific IgG tests were performed in parallel, a reference IgG deter- mination and a second test in which 6 M urea was added to the wash buffer as a protein denaturing agent to weaken the ...

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Development and validation of an Enzyme Linked Immunosorbent Assay (ELISA) test for the diagnosis of toxoplasmosis in Sri Lanka

Development and validation of an Enzyme Linked Immunosorbent Assay (ELISA) test for the diagnosis of toxoplasmosis in Sri Lanka

... antibody avidity test detects the IgG in the blood and it is very useful to identify a recent infection ...IgG avidity index shifts from low to high within 5 months of ...low avidity ...

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Human Immunodeficiency Virus (HIV) Antibody Avidity Testing To Identify Recent Infection in Newly Diagnosed HIV Type 1 (HIV 1) Seropositive Persons Infected with Diverse HIV 1 Subtypes

Human Immunodeficiency Virus (HIV) Antibody Avidity Testing To Identify Recent Infection in Newly Diagnosed HIV Type 1 (HIV 1) Seropositive Persons Infected with Diverse HIV 1 Subtypes

... guanidine-based avidity assay to that of the detuned ...guanidine-based avidity assay, and results were correlated to clinical, immunological, and virological parameters, including HIV-1 ...The ...

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Discrimination between Primary and Secondary Dengue Virus Infection by an Immunoglobulin G Avidity Test Using a Single Acute Phase Serum Sample

Discrimination between Primary and Secondary Dengue Virus Infection by an Immunoglobulin G Avidity Test Using a Single Acute Phase Serum Sample

... IgG avidity test described ...the avidity index was statistically different between the primary and secondary dengue infection serum ...the avidity index and the day of fever to ...

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Reliability of Immunoglobulin G Antitoxoplasma Avidity Test and Effects of Treatment on Avidity Indexes of Infants and Pregnant Women

Reliability of Immunoglobulin G Antitoxoplasma Avidity Test and Effects of Treatment on Avidity Indexes of Infants and Pregnant Women

... antitoxoplasma avidity test (Vidas; BioMe´rieux) is an immunoenzymatic test useful for excluding acute infection after the onset of ...The avidity index (AI) is the ratio of the signal in a test ...

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Development of Fully Automated Determination of Marker Specific Immunoglobulin G (IgG) Avidity Based on the Avidity Competition Assay Format: Application for Abbott Architect Cytomegalovirus and Toxo IgG Avidity Assays

Development of Fully Automated Determination of Marker Specific Immunoglobulin G (IgG) Avidity Based on the Avidity Competition Assay Format: Application for Abbott Architect Cytomegalovirus and Toxo IgG Avidity Assays

... IgG avidity assays, a high-avidity specimen with too much marker-specific IgG will give a false low-avidity reading, be- cause the blocking capacity of the soluble antigen is ...high avidity ...

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Seroreactivity to and Avidity for Recombinant Antigens in Toxoplasmosis

Seroreactivity to and Avidity for Recombinant Antigens in Toxoplasmosis

... The serum samples of case 1 were derived from a lymphad- enopathy patient who received no therapeutic treatment. In contrast, all pregnant women included in this study received therapeutic treatment either by spiramycin ...

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Evaluation of the New Elecsys Toxo IgG Avidity Assay for Toxoplasmosis and New Insights into the Interpretation of Avidity Results

Evaluation of the New Elecsys Toxo IgG Avidity Assay for Toxoplasmosis and New Insights into the Interpretation of Avidity Results

... If a seronegative pregnant woman receives systematic monthly follow-up, assessment of T. gondii-specific immunoglobulin G (IgG) and IgM antibodies allows the date of seroconversion (and, hence, infection) to be ...

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Isolation and characterization of human polyreactive pneumococcal polysaccharide antibodies

Isolation and characterization of human polyreactive pneumococcal polysaccharide antibodies

... body avidity between IgG1 and IgG2 forms of the same VH/VL pair in all ...antibody avidity and length of the VH CDR3 or be- tween avidity and number of mutations in either VH or VL or combined ...

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An affinity/avidity model of peripheral T cell regulation

An affinity/avidity model of peripheral T cell regulation

... The essential function of the immune system is to mount effec- tive immune responses to virtually any foreign antigens but avoid harmful immune responses to self. How developing T cells maintain tolerance to self while ...

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Immunoglobulin G Avidity in Diagnosis of Toxoplasmic Lymphadenopathy and Ocular Toxoplasmosis

Immunoglobulin G Avidity in Diagnosis of Toxoplasmic Lymphadenopathy and Ocular Toxoplasmosis

... IgG avidity results were between ...IgG avidity values of from ...high avidity results at the first examination in relation to the results at the reexamination 5 months later was 100% for 10 ...low ...

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High Throughput Multiplex Serological Testing in Microbiology

High Throughput Multiplex Serological Testing in Microbiology

... IgG avidity in SMIA for prediction of TBEV neutralization titer (Figure ...SMIA avidity testing contrasts with the necessity of running neutralization tests under biosafety level 3, involving handling of ...

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Anti-Leishmania infantum IgG Antibody Avidity in Visceral Leishmaniasis

Anti-Leishmania infantum IgG Antibody Avidity in Visceral Leishmaniasis

... High-avidity IgG antibodies predominated in patients with classic VL both upon general analysis of the bands and when the 14- and 16-kDa fractions were analyzed separately. This finding is consistent with the long ...

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TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

... on avidity of anti-intimin antibodies in mice infected repeatedly with ...the avidity of anti-intimin antibodies in serum was determined by the concentration of intimin needed to reduce the concentration of ...

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