Axon and myelin
Knockdown of Dock7 in vivo specifically affects myelination by Schwann cells and increases myelin thickness in sciatic nerves without affecting axon thickness
... enhanced myelin thickness without affecting axon thickness in sciatic nerves of the PNS, as reduced thickness of the axon diameter is the pri- mary indicator of denatured ...of myelin ...
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Donor mesenchymal stem cell-derived neural-like cells transdifferentiate into myelin-forming cells and promote axon regeneration in rat spinal cord transection
... into myelin-forming cells at 8 weeks. MSC-derived myelin- forming cells established myelin sheaths with the host regenerating ...their axon regener- ...
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Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury
... of myelin debris in SIRPα−/− mice compared with wild-type mice ...of myelin deb- ris in macrophages and microglia ...studied axon degeneration and re- generation ...of myelin debris removal ...
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The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans
... of axon regeneration appear to have been highly ...as myelin are absent, the ...of axon regrowth, both positive and ...and axon fragility to generate axon breakages, yet have typically ...
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Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation
... The myelin formation was markedly delayed in both Nogo-A ⫺/⫺ and MAG ⫺/⫺ mice, and even more in DOKO mice at ...P15. Axon diameters were concomitantly reduced, probably as a result of the myelination defect ...
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Concepts of Myelin and Myelination in Neuroradiology
... rat. Myelin wraps around the axon in multiple spirals to speed transmission of action ...of myelin. Myelin is composed of multiple layers having a protein-lipid-protein-lipid-protein ...the ...
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The molecular genetics of myelin genes
... the myelin sheath is fundamentally the same in the CNS and the PNS, but there are differences relating to the structure and organisation between the two ...of myelin is ...single axon, whereas ...
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Advances in noninvasive myelin imaging
... in myelin (Gulani et ...as axon density, caliber, cell swelling, fiber architec- ture and myelin thickness (Beaulieu, ...to myelin. MR based methods to estimate the myelin content in ...
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Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss
... of myelin is critical to its structure and function ...of myelin lamellae and myelinated axons [64]. Myelin sheaths are generated throughout life by preexist- ing or newly formed oligodendrocytes, ...
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Neurons define non-myelinated axon segments by the regulation of galectin-4-containing axon membrane domains
... The bivalent Gal-4 is capable to bridge glycans in a rather stable manner, stabilizing/organizing “superrafts” and yielding vesicle aggregation, proof for the concept of higher-order microdomain formation 32–34 . We show ...
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Myelin Recovery in Multiple Sclerosis: The Challenge of Remyelination
... new myelin sheaths render remyelinated lesions less intense with myelin stains (so-called “shadow plaques”) ...in myelin sheath domains in shadow plaques ...MOG-positive myelin and distinctive ...
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Myelin development, plasticity, and pathology in the auditory system
... and axon diameter are significantly greater along contralateral axon projections relative to ipsilateral projections (Seidl et ...the myelin adaptations identified in the gerbil sound localization ...
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Myelin-associated Glycoprotein and Myelinating Schwann Cell-Axon Interaction in Chronic 13,13"-Iminodipropionitrile Neuropathy
... All Schwann cell ingrowths identified in electron micrographs were stained intensely by MAG antise- rum in the adjacent 1-lim thick sections (Figs. 3-5).Most ingrowths arose from the bas[r] ...
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Axon Preinstallation
... Scope 2.0 S COPE • This information is correct for the Axon laser system as of July 2021. • The intended audience is Axon customers prior to delivery and during installation of their laser system. Any ...
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THE FORMATION AND STRUCTURE OF MYELIN
... This process is similar to myelinogenesis in the peripheral nervous system, a h h o u g h in central fibres the cytoplasm on the outside of the myelin is confine[r] ...
Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes
... specialized myelin extensions of their plasma mem- branes that surround axons normally enabling them rapid conduction of electrical ...and myelin where physical trauma occurs. Then, axons and myelin ...
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Axon Surface Infolding and Axon Size can be Quantitatively Related in Gastropod Molluscs
... The data of Mirolli & Talbott (1972) on the G-cell for both unstretched and stretched axons (Fig. 6A, open and filled circles, respectively) give values of the exponent in equation ([r] ...
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EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment
... single axon) were chosen. A single axon cut was made per ...by axon extension for a minimum of 50 ...of axon growth in the 14 h following ...
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Axon guidance in the inner ear
... classical axon repellents such as Semaphorins, Eph/ephrins and Slit/Robos may be involved in the pathfinding of otic ...otic axon guidance must also be ...
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Motor axon guidance in Drosophila
... While there are transcriptional regulators specifically expressed by subgroups of MNs one is expressed by all of them, Zfh1. Zfh1 is a zinc finger homeobox protein required for proper motor axon guid- ance of both ...
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