axonal regeneration
Growth-associated molecules and axonal regeneration
... inhibit axonal growth has been less weU investigated than that of white ...Little axonal regeneration has been reported in grey matter, although there are many examples where it has been shown to ...
400
The extracellular environment of the CNS : influence on plasticity, sprouting, and axonal regeneration after spinal cord injury
... after axonal injury in the mature CNS, including tenascins, semaphorins, ephrins, and netrins ...in axonal growth and ...with axonal extension, guidance, and growth cone formation ...axon ...
19
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation
... the regeneration and repair of the adult CNS after ...axon regeneration was found to depend on injury-related induction of the high-affinity folate receptor 1 ...the regeneration of afferent spinal ...
15
Original Article Transfection with AAV-NgR1siRNA on axonal regeneration of optic nerve after injury
... inhibition axonal regeneration after central nervous system (CNS) ...of axonal length between experimental and control ...the axonal regeneration of RGCs, while transfection of ...
6
Original Article Axonal regeneration of optic nerve after crush after PirBsiRNA transfection
... The PirA and PirB have been identified recently whereas these two genes share sequence simi- larity with a gene family [17]. It was confirmed that inactivation of either PirB or NgR alone could inhibit the growth-cone ...
6
Transplantation of Olfactory Mucosa as a Scaffold for Axonal Regeneration Following Spinal Cord Contusion in Rats
... Injuries to the central nervous system (CNS) in humans are usually associated with a low degree of neurological recovery and, in the majority of cases, life-long debilita- tion. This lack of recovery, however, is not due ...
5
Transplantation of Olfactory Mucosa Improve Functional Recovery and Axonal Regeneration Following Sciatic Nerve Repair in Rats
... Background: Olfactory ensheathing glia (OEG) has been shown to have a neuroprotective effect after being transplanted in rats with spinal cord injury. This study was conducted to determine the possible beneficial ...
6
<p>Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling</p>
... of axonal growth inhibitors after ischemic ...axon regeneration and reconnection after ...promotes axonal regeneration and protects damaged nerves by inhibiting Nogo-A/NgR1/RhoA/ROCKII/MLC ...
13
Original Article Gene silencing NMII promotes axonal regeneration against contusive spinal cord injury in rats
... Abstract: There are drastic changes that occur in the impaired regions after spinal cord injury (SCI), however, im- provement of the detrimental pathological process after injury is limited in the mammalian adult, which ...
8
Original Article MicroRNA-21 promotes axonal regeneration of peripheral nerve cells through regulating EPHA4 expression in schwann cells
... on axonal extension, providing a novel gene target for regeneration and repair after nerve ...respectively. Axonal growth of DRGns in different groups was ...expressions, axonal length in ...
10
Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
... Peripheral nerve injury triggers a local upregulation of selective UPR responses. To characterize the activation of the UPR after nerve crush, we monitored the expression of ER stress-responsive chaperones in sciatic ...
15
Original Article An inducible tyrosine kinase receptor for axonal regeneration
... injury. Regeneration remains a significant clinical problem, especially in cases when the trauma results in complete transection of the nerve, though autologous nerve grafting techniques has been skillfully used ...
12
In-silico and Molecular Analysis of Reticulon 4asNovel therapeutic option for axonal regeneration
... Fasudil and Nogoby docking analysis. Fasudil is also reported in the literature as a potential inhibitor for Nogo expression. By decreasing the expression of RTN4, one of the four inhibitors for damaged axonal ...
6
<p>Electroacupuncture Promoting Axonal Regeneration in Spinal Cord Injury Rats via Suppression of Nogo/NgR and Rho/ROCK Signaling Pathway</p>
... Several lines of evidence suggest that the signaling path- way of the Nogo protein/Nogo protein receptor (NgR) and the ras homolog gene/Rho-associated coiled coil-forming protein kinase may play a key role in mediating ...
14
The role of Nogo-A in axonal plasticity, regrowth and repair
... of axonal regeneration; it induces the quick destabilization of the actin cytoskeleton and, on a longer time scale, represses growth gene ...improves axonal growth and enhances behavioral recovery ...
8
RGD dependent mechanisms in the endoneurial phagocyte response and axonal regeneration in the nervous system of the snail Lymnaea stagnalis
... with 150· g·ml –1 gentamycin (Sigma Chemical Co., St Louis, MO, USA). Both right internal parietal (RIP) and right external parietal nerves were crushed as described previously (Hermann et al., 2000; Hermann et al., ...
11
Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3 kinase
... in axonal extension. Loss of p110d activity also dampened axonal regeneration following peripheral nerve injury in adult mice and impaired functional recovery of ...restored axonal extension ...
9
The disruption of mitochondrial axonal transport is an early event in neuroinflammation
... Mitochondrial transport in axons is extremely important to correctly locate the mitochondria at sites of higher energetic demand, such as the nodes of Ranvier and syn- aptic terminals, as well as for mitochondrial ...
15
Adenylyl cyclase dependent axonal targeting in the olfactory system
... How is this precise map elaborated and maintained? This process is not yet understood, but mounting evidence points to activity- dependent mechanisms (Yu et al., 2004; Zou et al., 2004). Odorant receptors (Mombaerts et ...
9
Autopsy findings in diffuse axonal injury statistical review
... Methods and Materials: 32 patients admitted to the neurosurgical ward of the Institute of Neurosurgery, Madras Medical College & RGGGH, between the period of October 2012 to March 2015, with Severe Head injury ...
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