azole resistant
Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus
... an azole-resistant strain (IFRC 500, Invasive fungi Research Center, Mazandaran University of Medical Sciences), previously isolated from Bronchoalveolar Lavage (BAL) and identified by molecular methods ...
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Culture Based Methods and Molecular Tools for Azole Resistant Aspergillus fumigatus Detection in a Belgian University Hospital
... Mycological cultures and susceptibility testing by azole resistance screening. A total of 212 positive samples for A. fumigatus were isolated from 109 hospitalized patients’ respiratory specimens, including 116 ...
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ERG11 Expression in Azole Resistant Candida species isolated from Diabetic Patients in a Tertiary Care Centre
... al). Azole-resistant ...of azole resistance among the most commonly encountered invasive Candida species remain low, with reported rates of ...
142
Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans
... other azole antifungal agents have proven effective in the management of OPC; however, with in- creased use of these agents, treatment failures have occurred that have been associated with the emergence of ...The ...
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Frequent detection of ‘azole’ resistant Candida species among late presenting AIDS patients in northwest Ethiopia
... be resistant to one or more antifungal agents tested which is relatively high compared with other similar studies from Africa [8,23,24] and the rest of the world ...were resistant to one or more antifungal ...
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Ncb2 Is Involved in Activated Transcription of CDR1 in Azole-Resistant Clinical Isolates of Candida albicans
... Candida albicans is an opportunistic human pathogen which mostly infects immunocompromised patients. It has gained considerable importance due to its ability to acquire resistance to a wide range of drugs during the ...
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AZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSIS
... to azole drugs has also been as- sociated with modifications of the ergosterol biosynthetic pathway, such as defects in the sterol C5,6-desaturation step that avoid the accumulation of the toxic 14α-methyl-3,6- ...
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Genome-Wide Expression and Location Analyses of the Candida albicans Tac1p Regulon
... additional azole-resistant isolates in which the Tac1p pathway is activated (Table 4), (ii) the TAC1 promoter contains a DRE motif, and (iii) Tac1p binds in vivo to its own promoter ...
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SYNERGISTIC ANTICANDIDAL ACTIVITY OF TWO TERMINALIA SPECIES WITH POLYENE AND AZOLE GROUP OF ANTIBIOTICS AGAINST MULTIDRUG RESISTANT CLINICAL ISOLATES OF CANDIDA
... in resistant antifungal strains, which is the result of widespread and repeated use of antibiotics and antifungal agents for a longer ...becoming resistant to AMP, a polyene antibiotic [15], and ...
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A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence
... to azole fungicides. These obser- vations confirm our concern that new azole resistance mutations will continue to emerge in the environment if we persevere with our current practices of azole ...
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Whole Genome Comparison of Aspergillus fumigatus Strains Serially Isolated from Patients with Aspergillosis
... of azole-resistant strains of Aspergillus fumigatus during treatment for aspergillosis occurs by a mutation selec- tion ...confer azole resistance, and it displayed an MIC indicating resistance to ...
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AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus
... with azole-resistant forms of Aspergillus fumigatus have a mor- tality rate that can approach 90% in particular patient populations (discussed in reference ...of azole drugs, lanosterol ␣ -14 ...
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<p>Mechanisms of azole resistance in clinical isolates of <em>Candida glabrata</em> from two hospitals in China</p>
... to azole antibiotics by increasing the expression of CgCDR1 and CgCDR2 or enhancing the virulence of yeast and plays a central role in fl uconazole resistance acquired by ...12 azole resistant ...
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Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole Genome Sequencing
... recombination and gene flow to homogenize the genetic back- ground upon which it occurs in Europe. The short branch lengths and high numbers of shared SNPs show that Indian isolates of A. fumigatus are broadly similar to ...
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Proteomic Differences between Azole Susceptible and Resistant Aspergillus fumigatus Strains
... [1]. Azole-resistance can occur primarily, when azole-resistant spores present in environmental air are inhaled, or secondary in a patient on long-term antifungal ...of azole-resistance is ...
23
UPC2 Is Universally Essential for Azole Antifungal Resistance in Candida albicans
... the azole antifungals in azole- resistant as well as azole-susceptible ...in azole antifungal activity against both azole-susceptible and azole-resistant strains of ...
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Investigation of cgrA and cyp51A gene alternations in Aspergillus fumigatus strains exposed to kombucha fermented tea
... ten azole-susceptible species and five azole-resistant strains, were obtained from the strain collection of Tehran Medical Mycology Laboratory (TMML), Tehran, ...
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In vivo activity of Sapindus saponaria against azole susceptible and resistant human vaginal Candida species
... Methods: The in vitro antifungal activity of HE, BUTE, fluconazole (FLU), and itraconazole (ITRA) was determined by the broth microdilution method. We obtained values of minimal inhibitory concentration (MIC) and minimum ...
9
In vitro antifungal activity of essential oils extracted from plants against fluconazole-susceptible and -resistant Candida albicans
... Lavender is an evergreen shrub from the Lamiaceae family. Lavender oil is consisted of more than 100 compounds, but linalool and linalylacetate are the most important ones [22, 23]. Pharma- ceutically, this plant has ...
6
The ABCs of Candida albicans Multidrug Transporter Cdr1
... The pioneer study that identified Cdr1p as a major player in mul- tidrug resistance (MDR) and implied its clinical relevance was carried out by Sanglard and his coworkers. That group used se- quential isogenic isolates ...
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