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B cell

Regulatory mechanisms of B cell responses and the implication in B cell-related diseases

Regulatory mechanisms of B cell responses and the implication in B cell-related diseases

... during B cell activation and dif- ...plasma cell dif- ferentiation and the etiopathogenetic mechanisms of the generation of B cell- or plasma cell-related diseases, such as ...

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B cell activity in children with malaria

B cell activity in children with malaria

... Mature B-cell population, expression level of CD21 and C3dg deposition in severe and uncomplicated malaria Lymphocytes were identified on the basis of their for- ward scatter (FSC) and side scatter (SSC) ...

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Paradox of B cell–targeted therapies

Paradox of B cell–targeted therapies

... whereas B cells are required for the expansion of autoantigen-specific T cells during disease ...regulatory B cells in humans, these findings not only resolve previously unexplained contradictions with ...

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B cell neoplasia in a developmental framework

B cell neoplasia in a developmental framework

... lnt J, De,', Bioi, 39 713 718 (1995) 713 SPecial Review B cell neoplasia in a developmental framework GEORGE KLEIN' Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden CONT[.] ...

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B cell responses in murine influenza

B cell responses in murine influenza

... TABLE 7.2 B Cell Memory in Murine Influenza Lung ASCs generated in vitro following: Primary Inoculation Spleen IgM IgG IgA IgM IgG IgA ++ ++ ++ +++ +++ + ++ ++ ++ ++ ++ - + + Secondary I[r] ...

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The Role of Morphogens in B Cell Development

The Role of Morphogens in B Cell Development

... of B cells into antibody producing B cells (Amu et ...of B cells into plasma cells (Dienz et ...control B cell survival and proliferation as it regulates Blimp-1via STAT-3 which drives ...

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MicroRNAs as B-cell lymphoma biomarkers

MicroRNAs as B-cell lymphoma biomarkers

... Abstract: B-cell lymphomas represent a group of more than 35 recognized mature B-cell neoplasms differentiated largely on the basis of immunohistochemical staining patterns that are often ...

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Checkpoints that control B cell development

Checkpoints that control B cell development

... 24–28). This secures continuous, life-long generation of new MPPs, CLPs, and common myeloid progenitors (CMP), and hence also B lymphocytes (21). Since only a fraction of the pool of LT-pHSCs is mobilized to ...

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MicroRNAs in B cell development and malignancy

MicroRNAs in B cell development and malignancy

... mature B cells [79-81]. Expression of miR-155 is rapidly induced in B cells after engagement of the antigen receptor and expo- sure to inflammatory mediators ...immune cell popu- lations; however, ...

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B cell selection and the development of autoantibodies

B cell selection and the development of autoantibodies

... immature B cells lead to reduced BCR ...autoreactive B cells leads to a substitution of tryptophan for arginine at residue 620 ...lower B-cell responses ...fewer B cells being deleted ...

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B cell depletion in autoimmune disease

B cell depletion in autoimmune disease

... immature B and mature B cells); this gives rise to plasma cells, which produce ...cells, B cells, cytokines and other elements within the immune system has been debated for decades, but the past 5 ...

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Mechanisms of B cell autoimmunity in SLE

Mechanisms of B cell autoimmunity in SLE

... autoimmune B cells created from non-autoreactive precursors by somatic ...c B cells in a T cell-dependent ...in B-cell development or may have defects in receptor ...autoreactive ...

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Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia

Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia

... PB B-cells and quantitation of immunoglobulin (Ig) levels was performed using high-sensitivity fl ow cytometry and nephelometry/ turbidimetry, ...PB B-cell subsets, together with the clinical and ...

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B cell origin of non T cell acute lymphoblastic leukemia  A model for discrete stages of neoplastic and normal pre B cell differentiation

B cell origin of non T cell acute lymphoblastic leukemia A model for discrete stages of neoplastic and normal pre B cell differentiation

... of B cell associated and restricted antigens on tumor cells isolated from 138 patients with non-T cell acute lymphoblastic leukemia (non-T cell ALL) was investigated by flow cytometric ...

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Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses

Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses

... Case Report: A thirty-year-old woman has applied to our department with a four month story of painless masses in both of breasts. We have performed tru-cut biopsies to both breasts after clinical examination. ...

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Original Article Characterization of the B cell response to Leishmania infection after anti-CD20 B cell depletion

Original Article Characterization of the B cell response to Leishmania infection after anti-CD20 B cell depletion

... induce B-cell depletion for 6 to 9 months, their immunoglob- ulin levels do not decrease ...memory B cell population [8]. Therefore, most patients receiving B-cell depletion ...

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Corruption of Human Follicular B-Lymphocyte Trafficking by a B-Cell Superantigen

Corruption of Human Follicular B-Lymphocyte Trafficking by a B-Cell Superantigen

... B1 B cells (12), S. aureus protein A inhibits B-cell chemotaxis to CXCL12 through downmodulation of surface CXCR4 ex- ...naïve B cells, SpA decreased the expression of SIgM and SIgD as ...

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Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

... of B-cell NHL. The T-cell rich B-cell lymphoma is a rare histological form accounting for 1–3 % of ...large B cells in a cellular background made of small cytotoxic lymphocytes ...

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Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

... In December 2011, a 57-year-old patient was referred to Endocrinology Outpatient Clinic because of focal lesion found on CT, which was located in left thyroid lobe. The patient was monitored since March 2011 due to ...

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The role of MerTK and BAFF in dendritic cell-B cell interactions

The role of MerTK and BAFF in dendritic cell-B cell interactions

... of B cell life history, ranging from the late transitional stages to differentiated plasma ...mature B cell pool by delivering a necessary pro-survival signal to resting B cells [152, ...

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