B-cell CLL/lymphoma 2
Curcumin regulates gene expression of insulin like growth factor, B cell CLL/lymphoma 2 and antioxidant enzymes in streptozotocin induced diabetic rats
... remedies must always be taken with caution as tox- icity studies have not been conducted for most of these plants [18,19]. Curcumin, the active ingredient from the spice turmeric is a potent antioxidant and ...
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Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance
... apoptotic cell death. BAX also forms heterodimers with Bcl-2 that leads to neutralisation of its apoptotic ...some cell lines of human haematopoietic malignancies [14] and colorectal cancers [15, 16] ...
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Altered expression pattern of miR-29a, miR-29b and the target genes in myeloid leukemia
... (myeloid cell leukemia sequence 1) and Bcl-2 (B-cell CLL/lymphoma 2) have been pre- dicted as potential target genes of miR-29 family and both of them belong to ...
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Organoid technology in disease modelling, drug development, personalized treatment and regeneration medicine
... BCL2: B cell CLL/lymphoma 2; CagA: cytotoxin associated gene A; Cas9: CRISPR-associated protein 9; CF: cystic fibrosis; CFTR: cystic fibrosis transmem- brane conductance regulator; ...
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Global expression profile of tumor stem-like cells isolated from MMQ rat prolactinoma cell
... coli 2; Bcl2: B-Cell CLL/lymphoma 2; bFGF: basic fibroblast growth factor; CCK-8: cell counting kit-8; Ccna2: cyclin A2; Ccnb2: cyclin B2; Cdc25a: cell division ...
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The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel
... – B-cell CLL/lymphoma 2; BRCA1 – breast cancer type 1 susceptibility protein; cDNA – complementary deoxyribonucleic acid; CTCF – CCCTC-binding factor (zinc finger protein) CtIP – ...
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Tumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapy
... kinase B; BRCA1: breast cancer 1; BLU: zinc finger MYND domain‑containing protein 10; BCL‑2: B cell CLL/ lymphoma 2; BTRC: beta‑transducin repeat containing E3 ubiquitin ...
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Spermatogonial Stem Cells: A Review of Essential Factor for Self-Renewal and Differentiation
... BCL6b: B cell CLL/lymphoma 6; bFGF: Basic fibroblast growth factor; EGF: Epidermal growth factor; ETV5: Ets variant gene 5; GDNF: Glial cell-derived neurotrophic factor; GnRh: ...
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Collision Anaplastic Large Cell Lymphoma (T Cell/Histiocyte Rich) and Diffuse Large B Cell Lymphoma: A Pathologic and Clinical Evaluation
... T-cell lymphoma and squamous cell carcinoma of the lung [2], Hodgkin’s disease and metastatic breast or cervical can- cer [3,4], Non-Hodgkin lymphoma and Kaposi sarcoma [5], ...
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Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)
... audible thyroid bruit. Lymph node packages with the diameter of 5 cm were palpable on the lateral surface of the neck, particularly on its left side. Hormone tests revealed normal levels of free thyroid hormones and ...
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Hepatitis B and C viruses and risk of non-Hodgkin lymphoma: a case-control study in Italy
... among B- cell NHL subtypes, whereas only two out of 37 (5.4 %) T-cell NHL cases were found to be positive for HCV ...large B-cell lymphoma (DLBCL; OR = ...zone lymphoma ...
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FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model
... MM cell lines PPM- MILL, PHI (originally denominated as HP3, [39]) and HMESO were established in tissue culture from surgi- cally resected MM specimens as described ...from Cell Applications, Inc (San ...
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Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders
... stromal cell-derived factor-1 (SDF1) and its receptor, C-X-C chemokine receptor type 4 (CXCR4) ...promising cell therapy source to understand neurotrophic factor-mediated ...
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Original Article Expressions and clinical significance of Bcl-2, Bcl-xL and c-IAP1 protein in cervical cancer
... of B-cell lymphoma 2 (Bcl-2), B-cell lymphoma xL (Bcl-xL) and cellular inhibitor of apoptosis protein 1 (c-IAP1) protein in cervical cancer and nor- mal cervical ...
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Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies
... The SHM status of the clonotypic rearranged immuno- globulin (Ig) heavy chain variable region (IGHV) gene is strongly associated with patient outcome [49]. Recently, the complete haplotype DNA sequence of the human Ig ...
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Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias
... aggressive CLL prompted us to determine whether this lncRNA is directly involved in disease ...3 cell lines but not in the fourth line (see Figure 1), the western result indicated that MIAT in malignant ...
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Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration
... Neurodegenerative disorders are frequent, incurable diseases characterised by abnormal protein accumulation and progressive neuronal loss. Despite their growing prevalence, the underlying pathomechanism remains unclear. ...
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CAR-T cell therapy: a potential new strategy against prostate cancer
... Based on the same hypothesis, other studies have evalu- ated CAR-T cells engineered to secrete different chemo- kines, such as CCL2 (involved in tumor homing and vascularization) [110]. Another way of enhancing T ...
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<p>Variability within the human <em>TERT</em> gene, telomere length and predisposition to chronic lymphocytic leukemia</p>
... TERT SNPs were chosen using the SNP Function Prediction tool of the National Institute of Environmental Health Sciences website and other auxiliary databases (https://snpinfo.niehs.nih.gov/snpinfo/snpfunc.html; https:// ...
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Development of aqueous based multi herbal combination using principal component analysis and its functional significance in HepG2 cells
... permeability transition which leads to release of caspases might have induced the apoptosis in HepG2 cells in present study. As far as we know, the present study of- fers recognition of potentially new ...
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