B-cell epitope
Identification and characterization of common B cell epitope in bovine leukemia virus via high throughput peptide screening system in infected cattle
... Results: We used a peptide microarray with 156 synthetic 15‑mer peptides covering the envelope glycoprotein gp51 and the Gag proteins p15, p24, and p12 to map B cell epitope and one B ...
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Computational Approach Used For Designing Of Potential B Cell Epitope Based Vaccine Construct Against Plasmodium Falciparum
... of B cell epitopes were also reported in databases but they were unable to achieve vaccine ...immunogenic B cell epitopes to design ...design B cell epitope vaccine ...
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Identification of B Cell Epitope of Dengue Virus Type 1 and Its Application in Diagnosis of Patients
... the B-cell ...S/T, b ⫽ ...the epitope for this antibody corresponded only to amino acid residues 111 to 116 of the NS1 of DEN-1 (Table ...linear epitope, and only DEN-1 reveals such a ...
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Study of B cell epitope conserved region of the Zika virus envelope glycoprotein to develop multi-strain vaccine
... the epitope, they used epitope prediction parameters such as antigenicity, flexibility, and hydrophilicity (Himmah et ...2016). B cell epitope prediction also used in the epitope ...
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Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice
... a B cell epitope derived from a Plasmodium yoelii circumsporozoite (CS) protein (referred to as the PyCS-B epitope) into the capsid proteins of WT/CS-GFP, a recombinant Ad expressing ...
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Identification of a novel linear B cell epitope in the UL26 and UL26 5 proteins of Duck Enteritis Virus
... identified epitope with those of another 14 alpha- herpesviruses revealed that the C-terminus of the linear B-cell epitope 521 YYPGE 525 is conserved among the selected alphaherpesviruses, ...
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Identification and characterization of a virus specific continuous B cell epitope on the PrM/M protein of Japanese Encephalitis Virus: potential application in the detection of antibodies to distinguish Japanese Encephalitis Virus infection from West Nile Virus and Dengue Virus infections
... These cross-reactive responses could confound the interpretation during serological testing, including neu- tralization tests and enzyme-linked immunosorbent assay (ELISA) [8]. JEV contains a single-stranded, posi- ...
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Computational Methods in Linear B cell Epitope Prediction
... To study the correlation between location of linear epitopes and amino acid scale based profiles, Blythe and Flower have performed an extensive estimation of 484 amino acid propensity scales in a dataset of 50 proteins ...
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Identification of a conserved linear B cell epitope in the M protein of porcine epidemic diarrhea virus
... Identification of B-cell epitopes on the M protein requires the preparation of McAb. To produce McAb against the M protein, we had tried to express the intact M protein, but this was unsuccessful (data not ...
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Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates
... defined epitope, which demonstrates less conserved between different CDV ...linear epitope, we ana- lyzed these sequences from Chinese isolates in domestic dogs during ...identified epitope, while ...
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Novel and frequent mutations of hepatitis B virus coincide with a major histocompatibility complex class I-restricted T-cell epitope of the surface antigen.
... Mutations within a known B-cell epitope (HBsAg 124-148). Consistent with previous reports (5, 11, 14, 34, 35), we found putative immune escape mutations within the group a deter- minant in 58% of the ...
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Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus.
... Humoral response to either the B-cell epitope peptide B, the T-helper cell epitope peptide T or the combination peptide T-B, using Quil A as an adjuvant Peptide used for immunization' B [r] ...
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Inclusion of a specific T cell epitope increases the protection conferred against foot and mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site
... virus-specific B and T-cell ...FMDV B-cell or B and T-cell epitopes (B and TB peptides, ...the B-cell epitope (site A) peptide or with TB, a peptide ...
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A Multiepitope Fusion Antigen Elicits Neutralizing Antibodies against Enterotoxigenic Escherichia coli and Homologous Bovine Viral Diarrhea Virus In Vitro
... Mouse antibody titration. Serum, fecal suspension, and intestinal wash samples from each mouse were examined for anti-K99, anti-STa, and anti-E2 IgG and IgA antibodies in ELISAs. To titrate anti-FanC anti- bodies, ...
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Advancement and applications of peptide phage display technology in biomedical science
... antibody B-cell epitope is cross-reactive to astrocyte elevated gene-1 (AEG-1), a human protein on human endothelial cells that may cause some dengue patients to suffer from hemorrhagic fever (DHF) ...
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Immunoinformatics Based Vaccine Design for Zea M 1 Pollen Allergen
... allergens. B-cell epitope mapping is a promising method to identifying the main antigenic determinants or epitopes of ...microorganisms. Epitope- based vaccines have outstanding approach ...
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IN SILICO HOMOLOGY STRUCTURE, B CELL AND T CELL EPITOPES PREDICTION OF SERINE/THREONINE PROTEIN KINASE A AGAINST TUBERCULOSIS
... in cell division, cell differentiation and cell ...with B-cell epitope and T-cell mapping that highlights the immunogenic part of a ...as B-cell ...
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Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes
... and B Cell Epitope Recognition in Arthritis 1683 grecan, when depleted of KS, induces a similar arthritis and ...arthritogenic epitope(s) responsible for this arthritis is located in the G1 ...
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Chronic development of collagen induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen
... and B cell epitope specificity in chronic CIA models; that is, with an active joint inflammation later than 6 weeks after the ...between epitope specificities and the different phases of the ...
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Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
... shared epitope of human leucocyte antigen (HLA) DR, smok- ing is associated with about a 20-fold increased risk of devel- oping anti-CCP antibody-positive RA ...
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