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B Lymphocytes

Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes

Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes

... in B lymphocytes (B-TRAF3 −/− mice), we recently reported that TRAF3 deletion leads to spontaneous development of MZL and B1 lymphoma in mice ...however, B lymphoma development in ...

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Do human B-lymphocytes avoid aging until 60 years?

Do human B-lymphocytes avoid aging until 60 years?

... whole B cell populations from young and early aged healthy donors under 60 ...that B cells avoid the aging program on molecular level until 60 years of ...uncompromised lymphocytes in early ...

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Multiple Mechanisms of Immune Suppression by B Lymphocytes

Multiple Mechanisms of Immune Suppression by B Lymphocytes

... by B lymphocytes was first reported on human and mouse B lymphoma cell lines ...on B-chronic lymphocytic leukemia cells and multiple myeloma cells as well as on nontransformed mouse and human ...

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The IgH 3′ regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate

The IgH 3′ regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate

... marrow B cell populations on the use of a 3’RR-deficient allele in competition with a wt ...peripheral B lymphocytes with an impact of the 3’RR deletion on IgH chain ...alters B cell fate by ...

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Trafficking of adoptively transferred B lymphocytes in B lymphocyte deficient mice

Trafficking of adoptively transferred B lymphocytes in B lymphocyte deficient mice

... B lymphocytes recirculate in the body along defined routes as they patrol the body in search of invading ...naive B cells enter secondary lymphoid organs from the blood and migrate through the T-cell ...

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CD40-Mediated Induction of CD4 and CXCR4 on B Lymphocytes Correlates with Restricted Susceptibility to Human Immunodeficiency Virus Type 1 Infection: Potential Role of B Lymphocytes as a Viral Reservoir

CD40-Mediated Induction of CD4 and CXCR4 on B Lymphocytes Correlates with Restricted Susceptibility to Human Immunodeficiency Virus Type 1 Infection: Potential Role of B Lymphocytes as a Viral Reservoir

... the B-cell compartment have been associated with HIV-1 pathogenesis, including polyclonal B-cell activation, hypergam- maglobulinemia, and follicular hyperplasia (19, 24, 27, ...CD40-stimulated B ...

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Studies on the Distribution of Surface Immunoglobulins on Human B Lymphocytes

Studies on the Distribution of Surface Immunoglobulins on Human B Lymphocytes

... immunoglobulin antibodies and shown to have a patchy distribution of immunoglobulin on their surfaces that does not form a cap after complexing with antibody. Use of freeze-etch electron microscopy confirmed the ...

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Peripheral blood T and B lymphocytes during acute rheumatic fever

Peripheral blood T and B lymphocytes during acute rheumatic fever

... blood lymphocytes were studied in 53 patients with acute rheumatic fever, diagnosed on the basis of modifified Jones ...another B-cell marker, the aggregated gamma globulin receptor, suggesting that such ...

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Infection of Human B Lymphocytes with Lymphocryptoviruses Related to Epstein-Barr Virus

Infection of Human B Lymphocytes with Lymphocryptoviruses Related to Epstein-Barr Virus

... immortalize B lymphocytes from the autologous species, but the ability of a given LCV to immortalize B cells from other Old World primate species is ...human B cells, and EBV did not ...

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B Lymphocytes in Untreated Patients with Malignant Lymphoma and Hodgkin's Disease

B Lymphocytes in Untreated Patients with Malignant Lymphoma and Hodgkin's Disease

... of B cells and low levels of serum ...of B lymphocytes per mm 3 of blood were ...of B lymphocytes showed very high serum ...monoclonal B cell proliferation in the peripheral ...

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Maintenance of Gammaherpesvirus Latency Requires Viral Cyclin in the Absence of B Lymphocytes

Maintenance of Gammaherpesvirus Latency Requires Viral Cyclin in the Absence of B Lymphocytes

... in B-cell- deficient ...of B cells, maintenance of v-cyclin-deficient viruses was equivalent to that of wild-type ␥ HV68 in the presence of B ...of B cells and raise the possibility that ...

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Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients

Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients

... of B lymphocytes, Lymphocytes from a dysgammaglobulinemic boy deficient in serum IgG and IgA, but who had normal numbers of IgM-, IgG-, and IgA-bearing B lymphocytes, could not be ...

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Multicomponent analysis of amino acid transport in human lymphocytes  Diminished L system transport in chronic leukemic B lymphocytes

Multicomponent analysis of amino acid transport in human lymphocytes Diminished L system transport in chronic leukemic B lymphocytes

... in B cell chronic lymphocytic leukemia and compared it with the amino acid transport in isolated B lymphocytes from human blood and ...blood B lymphocytes, which was 1,029 mumol/1 cell ...

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Role of the T and B lymphocytes in pathogenesis of autoimmune thyroid diseases

Role of the T and B lymphocytes in pathogenesis of autoimmune thyroid diseases

... Autoimmune thyroid disorders (AITD) broadly include Graves ’ disease and Hashimoto ’ s thyroiditis which are the most common causes of thyroid gland dysfunctions. These disorders develop due to complex interactions ...

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Developing Connections among B Lymphocytes and Deregulated Pathways in Autoimmunity

Developing Connections among B Lymphocytes and Deregulated Pathways in Autoimmunity

... investigated B lymphocytes as solely antibody-producing ...that B cells can exert a variety of functions within the immune system and ...result, B cells are considered promising targets for ...

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The Members of an Epstein-Barr Virus MicroRNA Cluster Cooperate To Transform B Lymphocytes

The Members of an Epstein-Barr Virus MicroRNA Cluster Cooperate To Transform B Lymphocytes

... transforms B lymphocytes through the expression of the latent viral proteins EBNA and latent membrane protein ...transform B lymphocytes in ...to B-cell ...to B-cell ...

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Positive and negative functions of B lymphocytes in tumors

Positive and negative functions of B lymphocytes in tumors

... some B lymphocytes can express the death-inducing molecule Fas ligand (FasL) and kill cells ...by B cells was first reported in 1996 [40]. Upon activation, mouse B cells lead to FasL ...

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Multiple Mechanisms of Immune Suppression by B Lymphocytes

Multiple Mechanisms of Immune Suppression by B Lymphocytes

... by B lymphocytes was first reported on human and mouse B lymphoma cell lines ...on B-chronic lymphocytic leukemia cells and multiple myeloma cells as well as on nontransformed mouse and human ...

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Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis

Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis

... (Figure 6A) by 46% at 6 months (P = 0.0048) and 41% at 9–12 months (P = 0.0058) compared with the place- Figure 2. Microarray analysis before and after siponimod treatment. In this experiment, 1531 differentially ...

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Virus Replication and Cytokine Production in Dengue Virus-Infected Human B Lymphocytes

Virus Replication and Cytokine Production in Dengue Virus-Infected Human B Lymphocytes

... PBMC, B cells, and monocytes, inoculated with virus immediately (4 h) after isolation from most donors were not permissive for DV ...of B cells to DV, as determined by measuring virus production, gradually ...

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