B2, bradykinin B2 receptor
In vivo bradykinin B2 receptor activation reduces renal fibrosis
... that bradykinin is involved in the control of a wide range of physiological functions, including car- diovascular homeostasis (regulation of systemic blood pressure and organ blood flow), water and electrolyte ...
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Infrared emitting, peptidase resistant fluorescent ligands of the bradykinin B2 receptor: application to cytofluorometry and imaging
... tion of human plasma. Am J Physiol Heart Circ Physiol. 2001;281:H275–83. 7. Fryer RM, Segreti J, Banfor PN, Widomski DL, Backes BJ, Lin CW, Ballaron SJ, Cox BF, Trevillyan JM, Reinhart GA, von Geldern TW. Effect of ...
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The design and synthesis of non-peptide bradykinin B2 receptor antagonists
... In peptides the amide bond framework serves as a structural matrix so that side chains are projected in defined spatial positions. A com bination of the appropriate side chain and projection then provides optimal ...
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The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury
... BB2: Bradykinin B2; BK: Brady- kinin; CT scan: Computerised Tomography of the head; CI: confidence interval; DSMB: Data Safety Monitoring Board; DRS: Disability Rating Scale; GCS: Glasgow Coma Scale; ...
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Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs
... At the level of the utero-placental unit, tilting the RAS/ KKS balance towards vasoconstriction caused fetal losses and placental insufficiency, and reduced the replacement of endothelium by endovascular trophoblasts in ...
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The relationship of Bradykinin B2 receptor gene variation with obesity, hypertension and lipid variables in obese patients
... of bradykinin C-58T genotypes for DBP levels showed them to be signifi- cantly higher in the C/C genotype carrying non-obese patients in comparison to those with the T/C genotype with Bonferronni corrected ...
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Gender-related associations of genetic polymorphisms of α-adrenergic receptors, endothelial nitric oxide synthase and bradykinin B2 receptor with treadmill exercise test responses
... cardiovascular performance during exercise testing. Therefore, we evaluated associations between functional genetic polymorphisms of α -adrenergic receptors, endothelial nitric oxide synthase, bradykinin ...
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Novel signaling of dynorphin at κ opioid receptor/bradykinin B2 receptor heterodimers
... 5-HT2A receptor agonists activate both Gq and Gi proteins when the 5-HT2A receptor forms heteromers with the mGlu2 receptor [58, ...orexin receptor 1 and KOR can form a heterodimer, which ...
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Wennerberg, Göran (2010): Role of the intracellular domains in the regulation and the signaling of the human bradykinin B2 receptor. Dissertation, LMU München: Medizinische Fakultät
... 37°C, receptor sequestration was inhibited by pretreatment of the cell monolayers on 24-well/48- wells with 100 µM phenyl arsine oxide (PAO) in incubation buffer for 5 min at ...
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Hereditary angioedema: what the gastroenterologist needs to know
... a bradykinin B2-receptor antagonist, or a kallikrein inhibitor as first-line therapy and solvent/detergent-treated or fresh frozen plasma as second-line therapy for acute ...
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Senescence associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
... the bradykinin B2 receptor increases the severity of a variety of senescence-associated changes that occur in untreated diabetic ...the B2 receptor on TBARSs and GSH were both highly ...
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Alternatives for the substitution of synthetic vitamin B2 or vitamin B2 produced from GMOs
... Vitamin B2 production, Andreas Gutzwiller from ALP pointed out that data on recommended amounts of vitamin B2 purveyance for swine are either older or come from the industry, and is therefore to be judged ...
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A Study on Surgical Management of Unstable Pelvic Fractures
... Radiological assessment was done with three standard views of x-rays (AP, inlet & outlet projections) and a CT scan whenever needed. 13 of the 21 cases suffered Tile’s type B injury against 8 cases of type C injury. ...
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Exploring the Horizons of Ephrin B2 Receptor for Combating Paramoxyviridae Infection
... The Hendra and Nipah viruses (HeV and NiV) are prominant members of the Paramyxoviridae family [1]. The initial cases were detected in Australia in 1994-95 and Malaysia in 1998-99. Henipa viruses have been transmitted to ...
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Journal of Applied Pharmaceutical Science
... Binding Site analysis is a fast detection program for the identification and visualization of possible binding sites and the distribution of surrounding residues in the active sites. The centre of active site was chosen ...
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Control of B2 bradykinin receptor gene expression
... of bradykinin for its receptor with associated slow dissociation, which would result in slow on set of ...its receptor is 1 nM (not unreasonable for a peptide agonist) and the microscopic association ...
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Alternativen zum Einsatz von synthetischem Vitamin B2 oder Vitamin B2 aus GVO Derivaten FiBL Empfehlung zur Vitamin B2 Problematik in der Biofuttermittelproduktion
... Auch das BLW lehnte eine Ausnahmebewilligung für Vitamin B2 ab. Diese wäre nur möglich, wenn einerseits die Nichtverfügbarkeit des synthetisch hergestellten Vitamins und andererseits die Notwendigkeit des ...
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Fibroblast like synovial cells from normal and inflamed knee joints differently affect the expression of pain related receptors in sensory neurones: a co culture study
... NK1 receptor-like IR in the co-culture system as well as DRG mono-cultures, and about 40% of the DRG neurones exhibit BK-gold binding in the co-culture sys- tem and DRG ...TRPV1 receptor was less widespread ...
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Moisture damage evaluation of aggregate–bitumen bonds with the respect of moisture absorption, tensile strength and failure surface
... Dry 24 hours 168 hours B1-L1 1920 ± 103 1390 ± 206 1384 ± 196 B1-G1 1947 ± 199 1351 ± 113 1293 ± 149 B1-G2 1938 ± 312 498 ± 143 371 ± 224 B2-L1 1425 ± 147 1203 ± 71 1078 ± 72 B2-G1 1386 ± 72 1248 ± 175 1062 ...
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An intronic SNP in the thyroid hormone receptor β gene is associated with pituitary cell specific over expression of a mutant thyroid hormone receptor β2 (R338W) in the index case of pituitary selective resistance to thyroid hormone
... Background: The syndrome of resistance to thyroid hormone (RTH) is caused by mutations in the thyroid hormone receptor b gene ( THRB ). The syndrome varies from asymptomatic to diffuse hypothyroidism, to ...
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