Basic fibroblast growth factor mitogenic assay
Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor
... platelets contained an inhibitor of bFGF-induced mitogenesis; this activity coeluted with PF 4 upon gel filtration, heparin-agarose, and ion-exchange chromatography. Purified thrombospondin and beta-thromboglobulin did ...
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Basic Fibroblast Growth Factor (bFGF), Fibroblast Growth Factor Receptor 1 (FGFR1), Transforming Growth Factor Beta (TGF-
... A moderate correlation was observed between bFGF and FGFR1 (Spearman’s rank correlation coefficient = .500, P < .001) as well as between bFGF and CgA (Spearman’s rank correlation coefficient = .311, P = .03). ...
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Effects of basic fibroblast growth factor on bone formation in vitro
... Basic fibroblast growth factor (bFGF) was studied for its effects on bone formation in cultured rat calvariae.. bFGF also increased the number of colcemid-induced metaphase arrested cell[r] ...
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Influence of Polycaprolactone and Basic Fibroblast Growth Factor on Gingival Fibroblasts
... Ex-vivo gingival explant cultures more closely mimic the in situ environment, as cells would be required to migrate through the collagenous ECM of the tissue to enter the scaffold. Therefore, we next investigated whether ...
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Basic fibroblast growth factor as a growth inhibitor for cultured human tumor cells
... Basic fibroblast growth factor (bFGF) stimulates the proliferation of many cells and it is found in a wide variety of normal or transformed ...(autocrine) growth inhibitor for cultured ...
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Serum levels of vascular endothelial growth factor and basic fibroblast growth factor in children with brain tumors
... the growth and spread of malig- nant ...environmental factor that induces ...endothelial growth factor (VEGF), thus stimulating tumor cells to produce and release cyto- kines, which trigger ...
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Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factor
... astrocyte growth are not well ...for growth regulation in these neural ...the basic fibroblast growth factor (bFGF) gene and ...
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Original Article Expression of vascular endothelial growth factor and basic fibroblast growth factor in extramammary Paget disease
... endothelial growth factor (VEGF) and basic fibro- blast growth factor (bFGF) in EMPD tissues and corresponding adjacent normal ...
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Treatment of corneal epithelial wounds in dogs using basic fibroblast growth factor
... This study also clearly demonstrated that the topical application of bFGF accelerated epithelial healing when the concentration exceeded 0.1 µg/ ml. Kitazawa (Kitazawa et al., 1990) reported that the effect of bFGF on ...
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Basic fibroblast growth factor stimulates endothelial regrowth and proliferation in denuded arteries
... endothelium ceases after approximately 6 wk, leaving a large area devoid of endothelium. Here we show that this cessation of reendothelialization can be overcome by the systemic administration of basic ...
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Basic fibroblast growth factor expression in isolated small human ovarian follicles
... [email protected] Basic fibroblast growth factor (bFGF) is involved in cell proliferation, differentiation, and ...and growth in vivo, we performed nested RT – PCR on ...
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Evaluation of salivary Basic Fibroblast Growth Factor (bFGF) in Tobacco Chewers with Chronic Periodontitis
... Delivery system for FGF: Due to their specific biologic functions and roles, FGF have the potential for application to induce the regeneration of a wide spectrum of tissuses, including skin, blood vessels, muscle, ...
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Evaluation of plasma basic fibroblast growth factor (bFGF) in primary knee osteoarthritis patients
... plasma basic fibroblast growth factor (bFGF) levels in patients with primary knee osteoarthritis (KOA) and to correlate it with physical performance, functional status and radiological ...
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Stimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bfgf)
... well-proliferated fibroblast and the well-produced collagens in the bioinspired hydrogels with bFGF-treated wound bed contribute to sig- nificantly enhance granulation tissue ...
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Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features
... Based on the above, we hypothesized that RV infection may also contribute to the fibrotic component of airway remodeling through bFGF, which may induce fibro- blast proliferation and regulate collagen turnover. We ...
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Bronchial Epithelial Cell Matrix Production in Response to Silica and Basic Fibroblast Growth Factor
... with fibrotic changes involved in tissue repair and lung fibrosis (17,18). To better understand the role of epithelial tissue in lung fibrosis, we conducted an electron and scan- ning microscopy study on a human ...
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Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation
... activation assay revealed that P9 reduced the levels of Erk1 and Erk2 phosphorylation in B16-F10 cells induced by ...tumor growth and blocked Erk1/Erk2 activation in the ...the mitogenic activity of ...
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Transcriptional induction of prostaglandin G/H synthase 2 by basic fibroblast growth factor
... cells, basic fibroblastic growth factor (bFGF) induced mRNA and protein for prostaglandin G/H synthase-2 (PGHS-2), the major enzyme in arachidonic acid (AA) conversion to ...
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Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts
... The effect of basic fibroblast growth factor (bFGF) administration on regional myocardial function and blood flow in chronically ischemic hearts was studied in 26 pigs instrumented with [r] ...
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Stimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bFGF)
... well-proliferated fibroblast and the well-produced collagens in the bioinspired hydrogels with bFGF-treated wound bed contribute to sig- nificantly enhance granulation tissue ...
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