BCG vaccination
Mucosal BCG Vaccination Induces Protective Lung Resident Memory T Cell Populations against Tuberculosis
... Mucosal BCG vaccination induced higher numbers of CD4 ⫹ and CD8 ⫹ T cells in the lung parenchyma between days 22 and 45 following BCG vaccination ...the vaccination routes ...100 ...
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Impact of BCG vaccination on incidence of tuberculosis disease in southern Ireland
... Three BCG vaccination policies were implemented across adjoining regions in the South West of Ireland from 1972; neonatal vaccination (vaccinated Region-A), vaccination of children aged 10 – ...
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Mucosal BCG vaccination induces protective lung-resident memory T cell populations against tuberculosis
... IMPORTANCE BCG remains the only licensed vaccine against ...administered BCG has variable efficacy against pul- monary TB, and thus, improved prevention strategies and a more refined understanding of ...
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An immuno-epidemiological study on the effect of Neonatal BCG vaccination on intracellular killing of Mycobacterium tuberculosis by human macrophages.
... superoxide dismutase (SOD) proteins which convert the toxic superoxide into molecular oxygen and hydrogen peroxide and thereby contribute to the survival of the bacilli (183). The contribution of superoxide dismutase in ...
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Diagnosis of latent tuberculosis infection in healthy young adults in a country with high tuberculosis burden and BCG vaccination at birth
... The BCG vaccine is not expected to have an effect on the QFT-GIT assay since the antigens that are contained in the assay are not present in any BCG strains ...the BCG vaccinated ...that BCG ...
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Early versus late BCG vaccination in HIV 1 exposed infants in Uganda: study protocol for a randomized controlled trial
... the BCG vaccine is best given to HIV- 1-exposed and uninfected children [35, ...whether BCG vaccination very early in life provides them with adequate protection against TB and other ...the ...
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Investigating the non specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial
... of BCG are ex- tremely ...altered BCG vaccination schedule ...receive BCG at birth had a 45% lower mortality rate (MRR ...had BCG immunisa- tion delayed to, on average, 6 weeks of ...of ...
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The association between Bacillus Calmette Guérin vaccination (1331 SSI) skin reaction and subsequent scar development in infants
... after BCG vaccination has been used as one of the indicators for successful vaccin- ation and in estimating vaccine coverage ...Since BCG is administered throughout the world as the only licensed ...
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Knowledge and attitudes of parents and professionals to neonatal BCG vaccination in light of recent UK policy changes: A questionnaire study
... We have found that awareness of this policy is generally quite limited, with one third of responders not knowing what BCG is and two thirds not knowing the current pol- icy for vaccination. It should be ...
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School based screening for tuberculosis infection in Norway: comparison of positive tuberculin skin test with interferon gamma release assay
... Only, 44 (9%) of the 511 TST positive children had a pos- itive QFT result. Positive QFT tests were seen with all sizes of TST indurations (Figure 1), although the proportion increased with the size of the TST ...
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Original Article Improved immunogenicity of mycobacterium tuberculosis Rv0577 by a heterologous prime-boost vaccination strategy in mice
... post- BCG vaccination boost with protein or DNA vac- cine of Rv0577 to immune BALB/c mice and the results suggested that the BCG prime- Rv0577 DNA boost vaccination could induce a durable Th1 ...
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Placental malaria is associated with attenuated CD4 T cell responses to tuberculin PPD 12 months after BCG vaccination
... While we detected an association between PM and reduced immune response to BCG vaccination at birth, the scope of the study did not extend to estab- lishing whether there was a direct causal link. Although ...
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BCG skin reaction in Mantoux negative healthy children
... whether BCG Test is positive because of prior BCG vaccination or due to natural tubercular ...exaggerated BCG Test response as a parameter to decide anti-tubercular therapy in patients in whom ...
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Humoral response to HspX and GlcB to previous and recent infection by Mycobacterium tuberculosis
... A total of 211 HCW were identified as infected by M. tb during the cross-sectional evaluation and were classified as a case of previous LTBI. Sixty seven HCW were excluded because they refused to participate or did not ...
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Persistence of the immune response induced by BCG vaccination
... to BCG vaccination in ado- lescents/young adults in the UK and Malawi ...whom BCG has been shown to provide 50–80% protection against pulmonary TB [7], showed little pre- existing T-cell response to ...
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BCG vaccination prevents reactivation of latent lymphatic murine tuberculosis independently of CD4+ T cells
... | BCG vaccination prevents reactivation of chronic lymphatic Mtb ...after vaccination with BCG or BCG 1 BCG1419c mice were infected ...25. BCG, Bacille Calmette–Guérin; ...
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Long term sex differential effects of neonatal Vitamin A supplementation on in vitro cytokine responses
... High-dose vitamin A supplementation (VAS) may affect mortality to infectious diseases in a sex-differential manner. Here, we analysed the long-term immunological effects of neonatal vitamin A supplementation (NVAS) in ...
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Re Assessing Tuberculin Skin Test (TST) for the Diagnosis of Tuberculosis (TB) among African Migrants in Western Europe and USA
... Interferon Gamma Release Assays (IGRAs) and TST are two tests currently used for screening latent TB in- fection and also aid for the diagnosis of active TB. IGRAs do not detect the actual TB bacilli, but instead they ...
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Repeated inoculations of Mycobacterium bovis Bacille Calmette Guérin (BCG) are needed to induce a strong humoral immune response against antigens expressed by the bacteria
... opsonized BCG by macrophages during the first hours after infection was significantly higher com- pared with the non-opsonized BCG (Figure ...the BCG cell surface accelerated the bacterial ...
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Comparative study of BCG vs BCG + Interferon Combination as Intravesical Therapy in Superficial Bladder Cancer.
... of BCG immunotherapy came in 1976, when Morales reported his clinical trial of BCG in 9 patients with recurrent tumours ...percutaneous BCG plus an instillation of 120 mg (10 9 colony-forming units ...
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