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BCL-2-associated protein X

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun

... gene-2 protein; Anxa11, Annexin A11; AP-1, activator-protein 1; Bax, Bcl-2 associated X protein; Bcl-2, B-cell lymphoma 2; CCK- 8, cell ...

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Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

... lymphoma 2 (BCL-2), BCL-2-associated X protein (BAX), Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), horseradish peroxidase (HRP)-conjugated don- key anti-rabbit ...

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Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

... the bcl-2 family proteins have been considered to play an important role in some types of cancers [12, ...The bcl-2 associated X, apoptosis reg- ulator gene is a member of the ...

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The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel

The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel

... BCL2-associated X protein; Bcl-2 – B-cell CLL/lymphoma 2; BRCA1 – breast cancer type 1 susceptibility protein; cDNA – complementary deoxyribonucleic acid; CTCF – ...

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Clarification of the molecular pathway of Taiwan local pomegranate fruit juice underlying the inhibition of urinary bladder urothelial carcinoma cell by proteomics strategy

Clarification of the molecular pathway of Taiwan local pomegranate fruit juice underlying the inhibition of urinary bladder urothelial carcinoma cell by proteomics strategy

... gene 2; Akt/PKB: protein kinase B; BAG2: BCL2-associated athanogene 2; BCL 10: B-cell lymphoma/leukemia 10; CAPZA1: F-actin-capping protein subunit alpha-1; CFL1: C ofilin; DUT: ...

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Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

... Bak: Bcl-2 homologous antagonist/killer; Bax: Bcl-2-associated X protein; EBV: Epstein-Barr virus; LMP-1: Latent membrane protein 1; LMP-2A: Latent membrane ...

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Current progress of mitochondrial transplantation that promotes neuronal regeneration

Current progress of mitochondrial transplantation that promotes neuronal regeneration

... The dynamic feature of mitochondria serves to adjust cellular metabolism according to physiological states [8, 9]. During early development, stochastic mitochondrial segregation leads to genetic drift effect, raising the ...

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Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders

Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders

... lymphoma 2-associated X protein; BBB: Blood – brain barrier; Bcl-2: B-cell lymphoma 2; BDNF: Brain-derived neurotrophic factor; BMMSC: Bone marrow-derived mesenchymal stem ...

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Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b

Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b

... Bax: Bcl-2-associated X protein; Bcl-2: B-cell lymphoma 2-related protein; cDDP: cisplatin; CDK1: cyclin-dependent kinase 1; DAPI: 4, ...

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The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma

The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma

... BAX: Bcl-2-associated X protein; BCL-2: B-cell lymphoma 2; bHLH: Basic-helix-loop-helix family of proteins; BMP: Bone morphogenic protein; CGNP: Cerebellar ...

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Original Article Role of gap junction protein 36 in pentetrazole-induced acute epilepsy in rats

Original Article Role of gap junction protein 36 in pentetrazole-induced acute epilepsy in rats

... and Bcl-2-associated X protein (Bax) at different time points (2, 4, 8, 12, and 24 h) after the occurrence of seizure was evaluated by he- matoxylin and eosin staining, ...

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Anti lipoapoptotic effects of Alisma orientalis extract on non esterified fatty acid induced HepG2 cells

Anti lipoapoptotic effects of Alisma orientalis extract on non esterified fatty acid induced HepG2 cells

... Bax, Bcl-2 associated X protein; Bcl-2, beta cell lymphoma 2; BSA, bovine serum albumin; COX-2, cyclooxygenase 2; DMEM, Dulbecco ’ s modified Eagle ’ ...

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Analysis of caspase-3 enzyme marker expression in oral squamous cell carcinoma: An Immunohistochemical study

Analysis of caspase-3 enzyme marker expression in oral squamous cell carcinoma: An Immunohistochemical study

... ( 2 3 ) Thes e rol es of caspas es have impl i cations for cancer s uch as moderat e act ivati on of caspas es could, cause cancer to progress rather than regress ...

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miR 1301/TRIAP1 Axis Participates in Epirubicin Mediated Anti Proliferation and Pro Apoptosis in Osteosarcoma

miR 1301/TRIAP1 Axis Participates in Epirubicin Mediated Anti Proliferation and Pro Apoptosis in Osteosarcoma

... SAOS- 2 cells were transfected with miR-NC inhibitors or miR-1301 inhibitors, and after 24-h transfection, cells were treated with epirubicin (1 μg/mL) for 48 ...

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Antiapoptotic Activity of the Herpesvirus Saimiri-Encoded Bcl-2 Homolog: Stabilization of Mitochondria and Inhibition of Caspase-3-Like Activity

Antiapoptotic Activity of the Herpesvirus Saimiri-Encoded Bcl-2 Homolog: Stabilization of Mitochondria and Inhibition of Caspase-3-Like Activity

... is associated with preven- tion of phosphatidylserine exposure depends on the particular antiapoptotic ...strategy. Bcl-x L also interfered with ...

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Ozone oxidative postconditioning inhibits oxidative stress and apoptosis in renal ischemia and reperfusion injury through inhibition of MAPK signaling pathway

Ozone oxidative postconditioning inhibits oxidative stress and apoptosis in renal ischemia and reperfusion injury through inhibition of MAPK signaling pathway

... Notes: nrK-52e cells were administered with vehicle, and different concentrations of OzoneOP or the MaPK inhibitors, sB-203580 (sB), U-0126 (U), or sP-600125 (sP), at a concentration of 15 μM for 2 h after h/r ...

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Clinical proteomics of myeloid leukemia

Clinical proteomics of myeloid leukemia

... only 2 to 4 months, and intensive chemo therapy, eventually in combination with allogeneic hematopoietic stem cell transplantation, is the only possibility for cure ...

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Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats

Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats

... The activation of MAPKs such as p38, ERK, and JNK is implicated in the inflammatory process of ALI/ARDS. The inhibition of p38, ERK, and JNK MAPK, effectively diminishes LPS and peritonitis-induced lung inflamma- tion ...

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PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway

PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway

... Triton X-100, and then the proteins were subjected to 10% sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and transferred to a polyvinylidene difluoride ...for Bcl-2, Bax, ...

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Original Article Expressions and clinical significance of Bcl-2, Bcl-xL and c-IAP1 protein in cervical cancer

Original Article Expressions and clinical significance of Bcl-2, Bcl-xL and c-IAP1 protein in cervical cancer

... of Bcl-2 is lower in cervical cancer, compared with normal cervical ...between Bcl-2 and the progno- sis of cervical cancer, Ozalp et ...that, Bcl-2, as a single variable, has no ...

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