Bcl-2 associated X
Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders
... lymphoma 2 (Bcl-2) expression in vascular endothelial cells ...factor Bcl-2 and reducing that of the apoptotic regulator Bcl-2-associated X protein (Bax) ...
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Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b
... lymphoma 2-related protein (Bcl-2) anti- bodies were from Beyotime (Shanghai, ...E1, Bcl-2-associated X protein (Bax), and proliferating cell nuclear antigen (PCNA) were ...
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ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun
... Bax, Bcl-2 associated X protein; Bcl-2, B-cell lymphoma 2; CCK- 8, cell counting kit-8; ECL, enhanced chemiluminescent; ECM, extracellular matrix; FBS, fetal bovine serum; ...
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Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?
... protein 2 (Bcl-2)-associated X (Bax) and Bcl-2, act as a promoter and an inhibitor of apoptosis, ...and Bcl-2 as well as their ratio have been regarded as ...
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Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway
... lymphoma 2 (BCL-2), BCL-2-associated X protein (BAX), Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), horseradish peroxidase (HRP)-conjugated don- key anti-rabbit IgG ...
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The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma
... BAX: Bcl-2-associated X protein; BCL-2: B-cell lymphoma 2; bHLH: Basic-helix-loop-helix family of proteins; BMP: Bone morphogenic protein; CGNP: Cerebellar granule neuron ...
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Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer
... Bak: Bcl-2 homologous antagonist/killer; Bax: Bcl-2-associated X protein; EBV: Epstein-Barr virus; LMP-1: Latent membrane protein 1; LMP-2A: Latent membrane protein 2A; EBER-1: ...
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Current progress of mitochondrial transplantation that promotes neuronal regeneration
... The dynamic feature of mitochondria serves to adjust cellular metabolism according to physiological states [8, 9]. During early development, stochastic mitochondrial segregation leads to genetic drift effect, raising the ...
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Clinical proteomics of myeloid leukemia
... Bax, Bcl-2 associated X protein; BCR-ABL, breakpoint cluster region-Abelson; CML, chronic myeloid leukemia; CMML, chronic myelomonocytic leukemia; CREB, cAMP response element-binding; CRKL, ...
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Original Article Role of gap junction protein 36 in pentetrazole-induced acute epilepsy in rats
... and Bcl-2-associated X protein (Bax) at different time points (2, 4, 8, 12, and 24 h) after the occurrence of seizure was evaluated by he- matoxylin and eosin staining, ...
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Anti lipoapoptotic effects of Alisma orientalis extract on non esterified fatty acid induced HepG2 cells
... Bax, Bcl-2 associated X protein; Bcl-2, beta cell lymphoma 2; BSA, bovine serum albumin; COX-2, cyclooxygenase 2; DMEM, Dulbecco ’ s modified Eagle ’ s ...
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Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance
... the bcl-2 family proteins have been considered to play an important role in some types of cancers [12, ...The bcl-2 associated X, apoptosis reg- ulator gene is a member of the ...
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The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel
... BCL2-associated X protein; Bcl-2 – B-cell CLL/lymphoma 2; BRCA1 – breast cancer type 1 susceptibility protein; cDNA – complementary deoxyribonucleic acid; CTCF – CCCTC-binding factor ...
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Expression of apoptosis related genes bax, bcl-2 and bcl-X in human gastric cancer: early results of an investigation
... if bcl-2 gene overexpression was mostly observed in the early stages of cancer, we also could not detect it also at protein level, probably due to post-transcriptional events and lack of protein ...
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Differential Expression of Viral Bcl-2 Encoded by Kaposi's Sarcoma-Associated Herpesvirus and Human Bcl-2 in Primary Effusion Lymphoma Cells and Kaposi's Sarcoma Lesions
... using X-ray ...and 2 l) were run on a Tricine gel and transferred to nitrocellulose ...for 2 h at room temperature with the prokaryotically produced GST–KSBcl-2 protein in 20 mM Tris HCl, pH ...
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Index Catalog // Carolina Digital Repository
... In addition to increased nuclease resistance, the PS modification confers enhanced protein binding (Brown et al., 1994). The reason PS ASOs bind more promiscuously to cellular proteins than PDE ASOs has not been fully ...
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Ozone oxidative postconditioning inhibits oxidative stress and apoptosis in renal ischemia and reperfusion injury through inhibition of MAPK signaling pathway
... Notes: nrK-52e cells were administered with vehicle, and different concentrations of OzoneOP or the MaPK inhibitors, sB-203580 (sB), U-0126 (U), or sP-600125 (sP), at a concentration of 15 μM for 2 h after h/r ...
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Differential responses of blood-brain barrier associated cells to hypoxia and ischemia: a comparative study
... [9,10]. Clearly, during injury conditions specific re- sponses of astrocytes and pericytes impact BBB mainten- ance and brain function. Both astrocytes and pericytes have been shown to support barrier function via tight ...
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miR 1301/TRIAP1 Axis Participates in Epirubicin Mediated Anti Proliferation and Pro Apoptosis in Osteosarcoma
... protein Bcl-2, Bax, cleaved-caspase-3, and poly (ADP-ribose) polymerase-1 (PARP1), were further exam- ...ined. Bcl-2 is an anti-apoptosis protein, and dysregulation of ...
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bcl 2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study
... the bcl-2 gene, an apoptosis inhibitor, in translocation 14;18 (q32;q21) in follicular B-cell lymphomas, followed by the identification of the BCL-2 family in the study of Caenorhabditis ...
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