bcl-2-Associated X Protein
ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun
... gene-2 protein; Anxa11, Annexin A11; AP-1, activator-protein 1; Bax, Bcl-2 associated X protein; Bcl-2, B-cell lymphoma 2; CCK- 8, cell ...
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Current progress of mitochondrial transplantation that promotes neuronal regeneration
... The dynamic feature of mitochondria serves to adjust cellular metabolism according to physiological states [8, 9]. During early development, stochastic mitochondrial segregation leads to genetic drift effect, raising the ...
12
Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b
... Bax: Bcl-2-associated X protein; Bcl-2: B-cell lymphoma 2-related protein; cDDP: cisplatin; CDK1: cyclin-dependent kinase 1; DAPI: 4, ...
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Original Article Role of gap junction protein 36 in pentetrazole-induced acute epilepsy in rats
... and Bcl-2-associated X protein (Bax) at different time points (2, 4, 8, 12, and 24 h) after the occurrence of seizure was evaluated by he- matoxylin and eosin staining, ...
6
The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma
... BAX: Bcl-2-associated X protein; BCL-2: B-cell lymphoma 2; bHLH: Basic-helix-loop-helix family of proteins; BMP: Bone morphogenic protein; CGNP: Cerebellar ...
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Anti lipoapoptotic effects of Alisma orientalis extract on non esterified fatty acid induced HepG2 cells
... Bax, Bcl-2 associated X protein; Bcl-2, beta cell lymphoma 2; BSA, bovine serum albumin; COX-2, cyclooxygenase 2; DMEM, Dulbecco ’ s modified Eagle ’ ...
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Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders
... lymphoma 2 (Bcl-2) expression in vascular endothelial cells ...factor Bcl-2 and reducing that of the apoptotic regulator Bcl-2-associated X protein ...
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Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway
... lymphoma 2 (BCL-2), BCL-2-associated X protein (BAX), Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), horseradish peroxidase (HRP)-conjugated don- key anti-rabbit ...
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Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer
... Bak: Bcl-2 homologous antagonist/killer; Bax: Bcl-2-associated X protein; EBV: Epstein-Barr virus; LMP-1: Latent membrane protein 1; LMP-2A: Latent membrane ...
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Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance
... the bcl-2 family proteins have been considered to play an important role in some types of cancers [12, ...The bcl-2 associated X, apoptosis reg- ulator gene is a member of the ...
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Clarification of the molecular pathway of Taiwan local pomegranate fruit juice underlying the inhibition of urinary bladder urothelial carcinoma cell by proteomics strategy
... gene 2; Akt/PKB: protein kinase B; BAG2: BCL2-associated athanogene 2; BCL 10: B-cell lymphoma/leukemia 10; CAPZA1: F-actin-capping protein subunit alpha-1; CFL1: C ofilin; DUT: ...
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The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel
... BCL2-associated X protein; Bcl-2 – B-cell CLL/lymphoma 2; BRCA1 – breast cancer type 1 susceptibility protein; cDNA – complementary deoxyribonucleic acid; CTCF – ...
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Antiapoptotic Activity of the Herpesvirus Saimiri-Encoded Bcl-2 Homolog: Stabilization of Mitochondria and Inhibition of Caspase-3-Like Activity
... Three protein factors, designated apoptotic protease-activating factors (Apaf-1, Apaf-2, and Apaf-3), were found to be necessary and sufficient to reconstitute dATP-dependent caspase-3 activation in such ...
8
Original Article Expressions and clinical significance of Bcl-2, Bcl-xL and c-IAP1 protein in cervical cancer
... tissues, Bcl-xL and c-IAP1 proteins were highly expressed in cervical cancer tissues, and Bcl-2 was lowly expressed in cervical cancer ...of Bcl-2 protein had significant ...
7
Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats
... Intracellular nicotinamide phosphoribosyltransferase (NAMPT), also called visfatin or pre-B cell colony- enhancing factor, is the rate-limiting enzyme in the sal- vage pathway for nicotinamide adenine dinucleotide (NAD) ...
12
miR 1301/TRIAP1 Axis Participates in Epirubicin Mediated Anti Proliferation and Pro Apoptosis in Osteosarcoma
... of Bcl-2, Bax, cleaved-caspase-3, and cleaved-poly (ADP-ribose) polymerase-1 (cleaved-PARP1) in U2OS and SAOS-2 cells were measured using Western ...*p<0.05. Bcl-2, B-cell ...
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COMPUTATIONAL PREDICTION OF PROTEIN INTERACTIONS IN BCL 2 PROTEIN AND THEIR ROLE IN APOPTOSIS
... target protein and drug ability of ...work protein functional region among mammals along with their interactions were studied in mitochondrial mediated ...proteins, Bcl-2 family of proteins ...
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Hepatitis C Virus Core Protein Modulates Endoglin (CD105) Signaling Pathway for Liver Pathogenesis
... important protein for tumor growth, sur- vival, and cancer cell ...binding protein 1 (ID1) were upregulated in HCV-infected cells or viral core gene-transfected ...core protein was depen- dent on the ...
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Original Article Repair of spinal cord injury in rats by subarachnoid transplantation of genetically modified schwann cells
... CO 2 incubator for 30 ...basic protein, MBP) at 4°C overnight using a wet ...for 2 h. Next the cells were stained with DAPI (4’,6-diamidino-2-phenylindole) for 10 min and washed with PBS three ...
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PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway
... the possible apoptosis pathways through which DNR-loaded NPs induced targeted chemotherapy, we assayed the expres- sions of some key apoptosis-associated proteins, including Caspase-3, Caspase-9, and c-PARP. In ...
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