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Behcet's Disease

Activated protein C resistance in Behcet’s disease

Activated protein C resistance in Behcet’s disease

... Behcet’s disease (BD), initially described by Hulusi Behcet in 1937, is a chronic multi-system disorder of unknown etiology with protean manifestations. The dis- ease is clinically characterized by ...

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A case report of REM sleep behavior disorder, Behcet’s disease, Sjogren’s syndrome and cognitive dysfunction

A case report of REM sleep behavior disorder, Behcet’s disease, Sjogren’s syndrome and cognitive dysfunction

... Behcet’s disease is especially common in Middle Eastern and Mediterranean ...The disease is characterized by oral and genital aphthous ulcers and ocular problems, including uveitis, retinal vasculitis and ...

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Experience of using adalimumab in treating sight-threatening paediatric or adolescent Behcet’s disease-related uveitis

Experience of using adalimumab in treating sight-threatening paediatric or adolescent Behcet’s disease-related uveitis

... result in prompt remission of BD-related uveitis. How- ever, the use of corticosteroid has to be judicious in chil- dren because of its significant side effects including steroid dependence, Cushing syndrome and impaired ...

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Intestinal and neurological involvement in Behcet disease: a clinical case

Intestinal and neurological involvement in Behcet disease: a clinical case

... Background: Behcets disease (BD) is a chronic immune-mediated, inflammatory disorder which may affect a number of different systems (oral and genital mucosa, eyes, skin, vascular district, joints, ...

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NOD2 is highly expressed in Behçet disease with pulmonary manifestations

NOD2 is highly expressed in Behçet disease with pulmonary manifestations

... T-bet is expressed preferentially by Th1 and natural killer (NK) cells, and its expression correlates to some extent with that of IFNg [26]. Numerically and function- ally increased Th1 cells are implicated in the ...

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Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet’s Disease in Saudi Population

<p>Genetic Polymorphisms in Transforming Growth Factor-&beta;, Interferon-&gamma; and Interleukin-6 Genes and Susceptibility to Behcet&rsquo;s Disease in Saudi Population</p>

... ’ s disease (BD) is a multi-systemic, chronic in fl ammatory disorder with the strong genetic background, characterized by recurrent oral aphthous, genital ulcer, uveitis, and skin ...this disease is ...

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The serum angiotensin converting enzyme and lysozyme levels in patients with ocular involvement of autoimmune and infectious diseases

The serum angiotensin converting enzyme and lysozyme levels in patients with ocular involvement of autoimmune and infectious diseases

... spondylitis, behcets disease, presumed sarcoidosis, presumed latent tuberculosis, presumed latent syphilis and control group Pairwise Comparison Mean Difference Standard Deviation ...

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Association between fibrinogen receptor (Glycoprotein IIb) polymorphism and the risk of venous thromboembolism: a systematic review

Association between fibrinogen receptor (Glycoprotein IIb) polymorphism and the risk of venous thromboembolism: a systematic review

... BD: Behcets disease; DVT: Deep vein thrombosis; FVL: Factor V Leiden; GP: Glycoprotein; PE: Pulmonary embolism; PLA1: Platelet antigen 1; PLA2: Platelet antigen 2; PRISMA: Preferred Reporting ...

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The role of inflammation in the development of epilepsy

The role of inflammation in the development of epilepsy

... BD: Behcets disease; CCL2: Chemokine (C-C motif) ligand 2; CCR2: C-C chemokine receptor type 2; CD: Celiac Disease; CNS: Central nervous system; COX: Cyclooxygenase; CSF: Cerebrospinal ...

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The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn’s disease

The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn’s disease

... BD: Behcets disease; CAI: Clinical Activity Index; CD: Crohn ’ s disease; CDAI: Crohn ’ s Disease Activity Index; CRP: C-reactive protein; ELISA: Enzyme-linked ...

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Disease-related information requirements in patients with Crohn&rsquo;s disease

Disease-related information requirements in patients with Crohn&rsquo;s disease

... the disease, patients tend to demand information about the prognosis of the disease, complications, risk of cancer, and etiology, but have a low demand for information about clinical ...the disease ...

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Neuroinflammation in Alzheimer&rsquo;s disease

Neuroinflammation in Alzheimer&rsquo;s disease

... AD treatment and every single factor represents an attrac- tive therapeutic target. But which one is the main cause of the process? There is usually no simple solution to complex problems and AD is sadly a complex ...

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Crohn&rsquo;s disease in women

Crohn&rsquo;s disease in women

... Among others, fistulization is a frequent complication of longstanding disease. Special attention has to be paid to women due to the possibility that fistulization may occur in the genitourinary tract, which can ...

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Parkinson&rsquo;s disease psychosis

Parkinson&rsquo;s disease psychosis

... Parkinson’s disease is a progressive neurodegenerative disease characterized by loss of nigral dopaminergic neurons associated with rigidity, resting tremor, bradykinesia, and postural ...Parkinson’s ...

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The genetics of Alzheimer&#39;s disease

The genetics of Alzheimer&#39;s disease

... Alzheimer’s disease (AD) is a complex and heterogeneous neurodegenerative disorder, classified as either early onset (under 65 years of age), or late onset (over 65 years of ...

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Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

... ’ s disease; AD-D: Alzheimer ’ s disease dementia; AD group: patients with Alzheimer ’ s disease (including mild cognitive impairment and dementia); AUC: Area under the curve; ...

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Posterior atrophy predicts time to dementia in patients with amyloid-positive mild cognitive impairment

Posterior atrophy predicts time to dementia in patients with amyloid-positive mild cognitive impairment

... and disease progression in our study is consistent with previous studies ...Otherwise, disease progression with brain atrophy could be affected by factors other than tauopathy, such as aging, traumatic ...

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Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer’s Coordinating Center Uniform Data Set

Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer’s Coordinating Center Uniform Data Set

... Clinical research diagnoses of cognitive status (i.e., NC; cognitively impaired, not MCI; MCI; dementia) were made at each UDS visit using established criteria for MCI [68, 69] and AD dementia [70, 71]. For versions 1 ...

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Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)

Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)

... Additional inclusion criteria for all groups were age ≥ 60 years, fluent German language skills, capacity to pro- vide informed consent, and presence of a study partner. The main exclusion criteria for all groups were ...

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Cerebral small vessel disease and Alzheimer&rsquo;s disease

Cerebral small vessel disease and Alzheimer&rsquo;s disease

... leads to dementia and contributes to neurodegenerative progress, including Alzheimer’s onset. Up to now, a number of studies have confirmed that CSVD can co-occur with AD, and signs of AD pathology have been found in ...

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