Beneficial Mutations
The Distribution of Fitness Effects Among Beneficial Mutations
... new beneficial mutations, a problem that partly reflects the rarity of these ...of beneficial fitness effects at a gene is ...of beneficial effects at a gene has the same mean regardless of ...
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Clonal Interference and the Periodic Selection of New Beneficial Mutations in Escherichia coli
... fixed beneficial mutations in the wild-type clones (R ozen et ...fixed mutations ( de V isser and R ozen 2005); both studies found results consistent with the clonal interference ...of ...
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Beneficial Mutations, Hitchhiking and the Evolution of Mutation Rates in Sexual Populations
... cally, beneficial mutations sweeping to fixation cause ify the values of various genetic ...the beneficial rates, they are subject to alteration through the action mutation arises, and so the ...
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The Pleiotropic Effects of Beneficial Mutations of Adapted Escherichia coli Populations
... with beneficial mutations does not appear to be directed towards antagonistic relationships in alternative ...of beneficial mutations gathered in a pre-adapted genotype, generally trend ...
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The Fates of Mutant Lineages and the Distribution of Fitness Effects of Beneficial Mutations in Laboratory Budding Yeast Populations
... these mutations are predicted to arise at a rate of order 10 25 per individual per ...1000 mutations confer a fitness advantage of two percent or ...adaptive mutations report a mix of loss-of-function ...
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A ruby in the rubbish: beneficial mutations, deleterious mutations and the evolution of sex.
... This expression embodies the assumptions of the model, since the in- finite population and infinite number of loci assump- tions imply that deleterious mutations will a[r] ...
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Survival Probability of Beneficial Mutations in Bacterial Batch Culture
... beneficial mutations can be extremely sensitive to the organism’s life history and the trait affected by the ...beneficial mutations in these ...of mutations that increase fitness through their effects ...
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Dynamics and Fate of Beneficial Mutations Under Lineage Contamination by Linked Deleterious Mutations
... beneficial mutations (Charlesworth et ...deleterious mutations (Birky and Walsh 1988; Bachtrog and Gordo 2004; Hartfield et ...deleterious mutations is the number of delete- rious mutations ...
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Mechanical interactions in bacterial colonies and the surfing probability of beneficial mutations
... Figure 13. (a) An example of an S. cerevisiae colony with beneficial mutants (yellow) forming sectors. The mutants have a growth rate advantage of s 10%. (b,c) Fate of mutant cells—experimental counterpart of ...
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The Effect of Linkage on Establishment and Survival of Locally Beneficial Mutations
... ABSTRACT We study invasion and survival of weakly beneficial mutations arising in linkage to an established migration–selection polymorphism. Our focus is on a continent–island model of migration, with selection at ...
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Diminishing Returns of Population Size in the Rate of RNA Virus Adaptation
... that beneficial mutations will arise in the most common genotype, improving its fitness, interfering with the intruder, and eventually removing the in- truder from the ...
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The effects of low-impact mutations in digital organisms
... for beneficial muta- tions and one for deleterious mutations, with each replicate consisting of eight experi- ments (one experiment for each fitness ...For beneficial mutations, experiments ...
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The Influence of Hitchhiking and Deleterious Mutation Upon Asexual Mutation Rates
... when beneficial mutations were available) but might then disappear after all such mutations had been ...lethal mutations of Taddei et ...of mutations at least approximately one- tenth ...
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Models of Experimental Evolution: The Role of Genetic Chance and Selective Necessity
... rare mutations and bottleneck effects, demonstrating how these increase variability in the evolutionary ...of beneficial mutations; when Np is large and selective pressure is strong, the ...
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The Speed of Adaptation in Large Asexual Populations
... populations, beneficial mutations have to compete with each other for ...mean beneficial effect of fixed mutations, under the assumptions that the population size N is large, that the mean ...
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Distributions of Beneficial Fitness Effects in RNA
... all beneficial mutations in the neigh- borhood of R ⱕ 4 wild-type sequences across the length of an adaptive ...one-step beneficial muta- tions from all low-rank wild-type alleles at that ...
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Effect of Population Size and Mutation Rate on the Evolution of RNA Sequences on an Adaptive Landscape Determined by RNA Folding
... of mutations, and effective population ...of mutations, and on population ...of beneficial mutations as population size increases, but larger populations still arrive at a higher mean ...of ...
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The Evolution of a High Mutation Rate and Declining Fitness in Asexual Populations
... disequilibrium between mutation rate modifier alleles and fitness-affecting loci, which is eroded by recombination. In recombining populations, mutation rate modifier alleles can be separated from the genetic background ...
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The survival probability of beneficial de novo mutations in budding viruses, with an emphasis on influenza A viral dynamics
... novo beneficial mutations a ff ecting five life-history traits: clearance, attachment, eclipse, budding, and cell ...that mutations a ff ecting clearance and cell death rate, two adaptive changes in ...
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GST: is IT Beneficial; A SWOT Analysis
... The Constitution Amendment Bill for Goods and Services Tax (GST) has been approved by the President of India; post its passage in the Parliament (Rajya Sabha on 3 August 2016 and Lok Sabha on 8 August 2016) and ...
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