beta 3-adrenergic receptors
Original Article Beta-3 adrenergic receptors could be significant factors for overactive bladder-related symptoms
... Overactive bladder (OAB) syndrome is defined as lower urinary tract symptom (LUTS) charac- terized by urgency, with or without urge inconti- nence, usually with frequency daytime and night time, in the absence of ...
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Endogenous sensitizer of beta-adrenergic receptors (ESBAR) and its analogs (review)
... of beta-AR (possibly due to inhibition of kinase of beta-AP, proteinkinase A and proteinkinase C) and accelerate the dephosphorylation of beta-AR by activating phosphatase, and (like chaperones) ...
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Loss of high affinity cardiac beta adrenergic receptors in dogs with heart failure
... We studied the alterations in myocardial beta-adrenergic receptor-adenylate cyclase activity and muscarinic receptor density in a canine model of left ventricular (LV) failure. LV failure was characterized ...
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Tissue distribution of beta 3 adrenergic receptor mRNA in man
... cognate receptors established by pharmacological studies. beta 3-AR transcripts were abundant in infant perirenal brown adipose tissue, characterized by the presence of uncoupling protein (UCP) ...
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Identification of beta adrenergic receptors in human lymphocytes by ( ) (3H) alprenolol binding
... mononuclear leukocytes. Binding of (-) [3H] alprenolol to these sites demonstrated the kinetics, affinity, and stereospecificity expected of binding to adenylate cyclase-coupled beta-adrenergic ...
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In Vitro Desensitization of Beta Adrenergic Receptors in Human Neutrophils ATTENUATION BY CORTICOSTEROIDS
... competition curves for [ 3 H]DHA binding. Desensitized receptors were characterized by rightward-shifted agonist competition curves. When hydrocortisone was added to the desensitizing incubations (combined ...
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Coregulation of calcium channels and beta adrenergic receptors in cultured chick embryo ventricular cells
... determinations were performed in similar intact cell preparations under identical conditions. 4-h exposure to 1 microM isoproterenol reduced cell surface beta-adrenergic receptor number from 44 +/- 3 ...
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Effects of pressure overload, left ventricular hypertrophy on beta adrenergic receptors, and responsiveness to catecholamines
... dP/dt. beta-adrenergic receptor binding studies with [3H]-dihydroalprenolol ( [3H]DHA) indicated that the density of binding sites was significantly elevated, P less than ...
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Autoradiographic characterization of beta adrenergic receptors in coronary blood vessels and myocytes in normal and ischemic myocardium of the canine heart
... pharmacologic and pathological stimuli. Blocks of canine left ventricle were frozen and tissue sections cut and incubated in (-)[3H]dihydroalprenolol (DHA) to label the BAR. For total and nonspecific binding, serial ...
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Beta adrenergic receptors in lymphocytes and granulocytes from patients with cystic fibrosis
... adenosine 3':5' cyclic monophosphate (cAMP) than normal lymphocytes in response to isoproterenol (10(-8)-10(-4) M), although the basal cAMP content and the response to prostaglandin E1 are ...the beta ...
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Beta Adrenergic Receptors of Polymorphonuclear Particulates in Bronchial Asthma
... systemic adrenergic medication (group 2), and 17 asthmatics receiving adrenergic agonists systemically (group ...no adrenergic drugs bound similar amounts of DHA at ...receiving adrenergic ...
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Genetic and epigenetic interactions in adaptive thermogenesis pathways in association with obesity from a Public Health Genomics perspective
... receptor beta-3 adrenergic receptor (ADRB3) responds to noradrenalin and mediates lipolysis in ...their receptors such as leptin and adiponectin have been identified as key factors modelling a ...
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Positive coupling of beta like adrenergic receptors with adenylate cyclase in the cnidarian Renilla koellikeri
... Although a substantial amount of work has been done on the effect of serotonin, dopamine and octopamine on adenylate cyclase systems in invertebrate tissues, few studies have been carried out on the stimulation of this ...
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PHARMACOKINETIC AND PHARMACODYNAMIC CHANGES IN ELDERLY PEOPLE
... Aging reflects all the changes that occur over the course of life, but in common usage, aging is often used to only mean senescence. [1] Usually, elderly is defined by a chronological age of 65 years or older. [2] Aging ...
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The Glucose Receptor A DEFECTIVE MECHANISM IN DIABETES MELLITUS DISTINCT FROM THE BETA ADRENERGIC RECEPTOR
... pancreatic beta adrenergic receptors and the implications of this relationship with regards to abnormal insulin secretion in diabetes mellitus, two questions were ...upon beta ...
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A paired sibling analysis of the beta 3 adrenergic receptor and obesity in Mexican Americans
... In humans, circulating leptin concentrations are highly cor- related with both body mass index and percent body fat (13, 14). We have recently localized a major quantitative trait locus (QTL) influencing serum ...
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Diabetes and beta adrenergic blockage are risk factors for metastatic prostate cancer
... Also, beta-adrenergic signaling has been associated with advanced prostate cancer [25] and beta-blockers have been associated reduced mortality in various tumor types ...unselective ...
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Exercise induced pulmonary vasoconstriction during combined blockade of nitric oxide synthase and beta adrenergic receptors
... of adrenergic receptors occurs with exercise, and because increased release in NO is hypothesized to occur during exercise, these studies were designed to determine the magnitude of effect and interactions ...
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Noncoordinate regulation of cardiac Gs protein and beta adrenergic receptors by a physiological stimulus, chronic dynamic exercise
... cardiac beta-adrenergic receptors and the stimulatory guanine nucleotide-binding protein, ...atrial beta-adrenergic receptors, but the dose of isoproterenol yielding a 50% ...
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Vascular Resistance Responses of an Eel Tail Preparation: Alpha Constriction and Beta Dilation
... Adrenaline AD and noradrenaline NA both increased vascular resistance, while isoprenaline decreased resistance which suggests the presence of both alpha and beta adrenergic receptors see[r] ...
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