beta interferon
The Infected Cell Protein 0 Encoded by Bovine Herpesvirus 1 (bICP0) Induces Degradation of Interferon Response Factor 3 and, Consequently, Inhibits Beta Interferon Promoter Activity
... inhibiting interferon-dependent ...human beta interferon (IFN-  ) ...reduces interferon response factor 3 (IRF3), but not IRF7, protein levels in transiently transfected ...
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The Infected Cell Protein 0 Encoded by Bovine Herpesvirus 1 (bICP0) Associates with Interferon Regulatory Factor 7 and Consequently Inhibits Beta Interferon Promoter Activity
... 8 NOTES The Infected Cell Protein 0 Encoded by Bovine Herpesvirus 1 bICP0 Associates with Interferon Regulatory Factor 7 and Consequently Inhibits Beta Interferon Promoter Activity䌤 Kazi[r] ...
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The Pathogenesis of Severe Fever with Thrombocytopenia Syndrome Virus Infection in Alpha/Beta Interferon Knockout Mice: Insights into the Pathologic Mechanisms of a New Viral Hemorrhagic Fever
... alpha/beta interferon receptor knockout (IFNAR ⴚ/ⴚ ) mice were highly susceptible to SFTSV infection, and all mice died within 3 to 4 days after subcutaneous inoc- ulation of 10 6 focus-forming units of ...
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Respiratory Syncytial Virus Regulates Human MicroRNAs by Using Mechanisms Involving Beta Interferon and NF κB
... (IFNs). Beta interferon (IFN-  ) treatment induced human miR-155 expression in cells in a Jun N-terminal protein kinase (JNK)-dependent fashion, possibly dependent upon tumor ne- crosis factor alpha ...
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Bacterial lipopolysaccharide and gamma interferon induce transcription of beta interferon mRNA and interferon secretion in murine macrophages.
... 2785-2789 0022-538X/89/062785-05$02.00/0 Copyright C 1989, American Society for Microbiology Bacterial Lipopolysaccharide and Gamma Interferon Induce Transcription of Beta Interferon mRN[r] ...
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“Self” and “Nonself” Manipulation of Interferon Defense during Persistent Infection: Bovine Viral Diarrhea Virus Resists Alpha/Beta Interferon without Blocking Antiviral Activity against Unrelated Viruses Replicating in Its Host Cells
... alpha/beta interferon (IFN- ␣ /  ) synthesis by double-stranded RNA ...the interferon defense system may be a key element in the success of persistent infection in addition to immunotolerance ...
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Impaired Antiviral Response and Alpha/Beta Interferon Induction in Mice Lacking Beta Interferon
... At least two mechanisms can be envisaged to explain such a unique role for IFN-. In the first, IFN␣ and IFN genes may be independently induced by viral infection, but IFN- may specifically induce one or more genes ...
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Regulation of the human beta-interferon promoter
... The ability of the ubiquitous Oct-1 protein to utilize a B cell specific cofactor in order to carry out octamer-specific activation o f transcription challenges the[r] ...
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Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon.
... Effects of IFN-y or IFN-cx/1 on the replication of LCMV isolates in mice or in cell cultures" Virus titer differences log,0 between treated and control cultures Tendency of virus to pers[r] ...
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Cell Type Specific Effects of RNase L on Viral Induction of Beta Interferon
... ABSTRACT The interferon (IFN)-inducible antiviral state is mediated in part by the 2=,5=-oligoadenylate (2-5A) synthetase (OAS)/ RNase L system. 2-5A, produced from ATP by OAS proteins in response to viral ...
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Posttranscriptional regulation of beta interferon expression in erythroid Friend cells treated with gamma interferon.
... With respect to IFN-P induction, IFN--y appears unable to induce IFN-f production in HeLa cells, in which constitutive transcription of the IFN-P gene is undetectable before and after IF[r] ...
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The secRNome of Listeria monocytogenes Harbors Small Noncoding RNAs That Are Potent Inducers of Beta Interferon
... ABSTRACT Cellular sensing of bacterial RNA is increasingly recognized as a deter- minant of host-pathogen interactions. The intracellular pathogen Listeria monocyto- genes induces high levels of type I interferons ...
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Cytokine Responses in Severe Acute Respiratory Syndrome Coronavirus-Infected Macrophages In Vitro: Possible Relevance to Pathogenesis
... The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear. Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to compare the responses of human macrophages to ...
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Renal thrombotic microangiopathy caused by interferon beta-1a treatment for multiple sclerosis
... 26. Herrera WG, Balizet LB, Harberts SW, et al. Occurrence of a TTP-like syndrome in two women receiving beta interferon therapy for relaps- ing multiple sclerosis [American Academy of Neurology 51st ...
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Interferone und Natalizumab in der Behandlung der multiplen Sklerose (MS) Interferons and Natalizumab for Multiple Sclerosis
... of beta-interferon therapy, one in patients with secondary progressive MS, the remainder in patients with relapsing remitting ...assessed interferon therapy for patients with relapsing remitting ...
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Human immune responses to Plasmodium falciparum infection: molecular evidence for a suboptimal THαβ and TH17 bias over ideal and effective traditional TH1 immune response
... Although interferon alpha/beta was not detected in this study, the major transcription factor of interferon alpha/beta synthesis, IRF7, was up- regulated after ...Many interferon ...
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Type I Interferon Response Limits Astrovirus Replication and Protects against Increased Barrier Permeability In Vitro and In Vivo
... Here we show that human astrovirus type 1 HAstV-1 infection induces type I interferon beta interferon [IFN-] production in differentiated Caco2 cells, which not only inhibits viral repl[r] ...
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The role of glatiramer acetate in the early treatment of multiple sclerosis
... From the healthcare provider position, therapy choices are based on a balance of efficacy, tolerability and safety. Furthermore, as with many other fields of medicine, the prior experience and training of each provider ...
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Emerging oral immunomodulating agents – focus on teriflunomide for the treatment of multiple sclerosis
... Results of a small double-blind, placebo-controlled Phase II study of teriflunomide as adjunctive therapy with IFN- β were presented at the European Committee for Treat- ment and Research in Multiple Sclerosis (ECTRIMS) ...
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Cycloheximide induces expression of the human interferon beta 1 gene in mouse cells transformed by bovine papillomavirus-interferon beta 1 recombinants.
... 1 0022-538X/83/070089-07$02.00/0 Copyright © 1983, American Society for Microbiology Cycloheximide Induces Expression of the Human Interferon P Gene in Mouse Cells Transformed by Bovine [r] ...
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