Bifunctional Enzyme
Peroxisomal bifunctional enzyme deficiency
... the bifunctional enzyme (enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase) was deficient in postmortem liver samples, whereas acyl-CoA oxidase and the mature form of beta-ketothiolase were ...
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NAD(H) recycling activity of an engineered bifunctional enzyme galactose dehydrogenase/lactate dehydrogenase
... artificial bifunctional enzymes composed of enzymes in the citric acid cycle, ...of bifunctional enzyme [23, 24, ...scavenger enzyme assay in vitro in which diaphorase is competing for the ...
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Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum
... a bifunctional enzyme, with FPPS/ GGPPS activity, producing FPP and ...only enzyme leading to the precursors for the synthesis of larger polyisoprenoids; and, iii) that FPPS/ GGPPS has major ...
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Chlamydia trachomatis dapF Encodes a Bifunctional Enzyme Capable of Both d Glutamate Racemase and Diaminopimelate Epimerase Activities
... We postulated that pathogenic chlamydiae possess a bifunctional enzyme capable of generating D -Glu for the synthesis of peptidoglycan. Racemases and epimerases both FIG 1 Missing enzymatic activities in ...
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Overexpression of artificially fused bifunctional enzyme 4CL1–CCR: a method for production of secreted 4-hydroxycinnamaldehydes in Escherichia coli
... In summary, we have demonstrated the in vivo biocon- version of phenylpropanoic acids to 4-hydroxycinna- maldehydes using E. coli overexpressing the bifunctional enzyme 4CL1–CCR. Overexpression of the fused ...
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Studies on a bifunctional enzyme from Escherichia coli : purification, properties and kinetic characteristics of chorismate mutase-prephenate dehydrogenase
... the aromatic amino acid aminotransferase associates noncovalently with both the bifunctional enzymes chorismate mutase-prephenat e dehydrogenase and chorismate mutase-prephenat e dehydra[r] ...
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Overexpression of a bifunctional enzyme, CrtS, enhances astaxanthin synthesis through two pathways in Phaffia rhodozyma
... The large observed increase in astaxanthin suggested that it was not the inhibitor of this multi-enzyme reac- tion sequence. Our kinetic studies of mRNA expression patterns of structural carotenogenic genes and ...
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Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling
... last enzyme in this pathway and is a cytosolic enzyme that includes a transformylase do- main, which transfers a formyl group to AICAR to produce the intermediate formyl-AICAR (FAICAR) and IMP ...
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The Drosophila melanogaster ade5 Gene Encodes a Bifunctional Enzyme for Two Steps in the de novo Purine Synthesis Pathway
... ties, it is likely that the Drosophila AIRc enzyme func- tions in a similar fashion to the chicken AIRc. It has been proposed that the chicken AIRc is capable of sub- stituting for both PurE and PurK because it ...
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Fast and reliable production, purification and characterization of heat-stable, bifunctional enzyme chimeras
... two enzyme chimeras CB and BC composed of an endo- glucanase Cel5A (C) from the extreme thermophilic bacterium Fervidobacterium gondwanense and an archaeal β-glucosidase Bgl1 (B) derived from a hydrothermal spring ...
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3. Hui Zeng, Li Yang, Hua Rong, Weiwei Zhang, Feng Xu and Xin Zhang
... biloba , function analysis indicated that GbFLS is a bifunctional enzyme within the flavonol biosynthetic pathway, recombinant GbFLS1 protein could... In the current stud[r] ...
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Chloroviruses Encode a Bifunctional dCMP-dCTP Deaminase That Produces Two Key Intermediates in dTTP Formation
... the enzyme to make the active site of the enzyme more suitable for dCMP and more efficient for the deamination ...the enzyme. Therefore, the enzyme presumably has two dCTP binding sites, one ...
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In silico experimentation with a model of hepatic mitochondrial folate metabolism
... mitochondrial bifunctional enzyme The mitochondrial bifunctional enzyme is active during embryonic development and in transformed cells [17,24], but not in the adult ...the bifunctional ...
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Characterization of a bifunctional catalase-peroxidase of Burkholderia cenocepacia.
... chronic infection and inflammation. Although members of the “B. cepacia complex” display catalase and peroxidase activities [8], we have generally found that these activities in other species of the complex are very low ...
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Phase Transfer Catalyzed Selective Reduction of Bifunctional Moieties
... Reduction of bifunctional moieties to the corresponding alcohol is useful and one of the most important transformation in synthetic organic chemistry. Chemoselective reduction of one functional group in the ...
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Bifunctional Role of Thiosalicylic Acid in the Synthesis of Silver Nanoparticles
... The ability of three different synthesis methodologies – direct heating, photochemical and microwave dielectric treatment were evaluated and assessed on the basis of the size, size distr[r] ...
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Asymmetric Michael addition using sugar derived organocatalysts
... 18. Gao, P., Wang, C., Wu, Y., Zhou, Z., & Tang, C. (2008). Sugar‐Derived Bifunctional Thiourea Organo- catalyzed Asymmetric Michael Addition of Acetylace- tone to Nitroolefins. European Journal of Organic ...
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Characterization of Afb, a novel bifunctional protein in Streptococcus agalactiae
... S. agalactiae also possess a dynamic structure called peptidoglycan. This structure like other Gram-positive bacterial cell wall contains peptido- glycan hydrolases. These enzymes play an important role in remodeling, ...
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Catalyzed Schiff Base synthesis over Bifunctinalized Cobalt/Zinc-Incorporated Mesoporous Silica Nanoparticles under UV irradiation
... structured-bifunctional catalysts of CZ-X-MSN (X=1,3 and 5) exhibited the high conversions, selectivity and yields in comparison with the other samples possess mono-functional structures possibly due to the ...
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Synergistic organocatalysis in the kinetic resolution of secondary thiols with concomitant desymmetrisation of an anhydride
... To test this hypothesis, in preliminary experiments we carried out the acylative KR of the racemic sec-thiol 1 with glutaric anhydride (2a) in the presence of bifunctional (thio)urea-derived organocatalysts 10-12 ...
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