Biological evaluation
Design, Synthesis and Biological Evaluation of Novel Cannabinoid Antagonist
... Design, Synthesis and Biological Evaluation of Novel Cannabinoid Design, Synthesis and Biological Evaluation of Novel Cannabinoid Antagonist.. Antagonist.[r] ...
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Synthesis and biological evaluation of indoles
... A large number of structural analogues of serotonin have been synthesized and their biological activities evaluated in recent years. In contribution of previous work [29] we report here the synthesis of various ...
11
Design Synthesis, Characterization and Invitro Biological Evaluation of Novel Series of 1- Substituted Isatin Derivatives by Mannich Reaction.
... This is to certify that the dissertation entitled – DESIGN SYNTHESIS, CHARACTERIZATION AND INVITRO BIOLOGICAL EVALUATION OF NOVEL SERIES OF 1- SUBSTITUTED ISATIN DERIVATIVES BY MANNICH REACTION was done by ...
144
Design Synthesis Characterization and Biological Evaluation of Some Novel Benzothiazole Derivatives as Anti Tubercular Agents Targeting Glutamine Synthetase 1
... AND BIOLOGICAL EVALUATION OF SOME NOVEL BENZOTHIAZOLE DERIVATIVES AS ANTI-TUBERCULAR AGENTS TARGETING GLUTAMINE SYNTHETASE 1 ” submitted by the candidate bearing the Register No:261515701 in partial ...
118
Preparation and biological evaluation of c derivatives
... Preparation and biological evaluation of 7/8/9-Substituted - 10 – N-[(carboxymethyl)-sulfanylacetyl]-phenothiazine - 1 - carboxylic acids. 7/8/9-Substituted 10-N-[bis ...
5
The Design, Synthesis, and Biological Evaluation of Steroid-Derived Inhibitors of the Sonic Hedgehog Signaling Pathway
... high-throughput biological evaluation, we are continuing to design and synthesize novel antagonists of the SHH pathway in hopes to further understand the binding pocket of ...
440
Synthesis, Characterization and Biological Evaluation Of 2-Azetidinone and 4-Thiazolidinone Derivatives.
... With great respect and honor, I extend my thanks to THIRUMATHI LAKSHMI BANGARU ADIGALAR, Vice President, ACMEC Trust, Melmaruvathur for given me an opportunity and encouragement all the way in completing the study. Her ...
157
Biological evaluation of some quinoline derivatives
... Nitrogen containing heterocyclic compounds like quinoline has received considerable attention in recent years, due to their biological and pharmaceutical activities. These derivatives are known to have wide ...
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Synthesis and biological evaluation of delavayin-C
... significant biological activities exhibited by various cyclic peptides, as a part of ongoing study, an attempt was made towards the synthesis of a cyclic heptapeptide, delavayin-C, cyclo(gly-tyr- ...
5
Phytochemical and Biological Evaluation of Justica adhatoda
... and biological investigations were undertaken on ethanolic extracts of the Alkaloids, cardiac glycosides, tannins, steroids and from both parts of the title ...
5
Synthesis and biological evaluation of triazine derivatives
... 1, 2, 4-triazine heterocyclic entity are very interesting components in terms of their biological properties, such as antifungal, antibacterial and herbicidal. Synthesized compounds 4a-4l were tested against a ...
10
Synthesis, functionalisation and biological evaluation of tetrahydroxanthones
... the biological effects of the new dihydroxanthones, dihydroxy, and trihydroxytetrahydroxanthones synthesised in the laboratory were evaluated against human pancreatic cancer cell line (PANC-1), grown separately in ...
189
Biological evaluation of hydroxynaphthoquinones as anti malarials
... Conclusions: N3 was a potent inhibitor of mitochondrial electron transport, had nanomolar activity against cultured Plasmodium falciparum and showed minimal cytotoxicity.. N3 may serve a[r] ...
6
Design, Synthesis, Characterization and Biological Evaluation of Pim-1 Inhibitor for Anticancer Activity.
... visual evaluation procedure is used to select the best model comparing the regression graphs, obtained by correlating the train set data, Using the compare fit it was seen how the most active compounds map to the ...
148
Synthesis and Biological Evaluation of N-heterocycles for Activity on Monoamine Transporters and Exploration of Iridium Chemistry for Synthesis of Medicinally Important Molecules
... The focus of these studies has been toward the development of new synthetic methods and procedures for the synthesis of novel compounds with unique biological properties. This research has led to the development ...
167
Synthesis, Biological Evaluation and Molecular
... The observed increased cytotoxicity of compounds 5e–h against the A549 and HeLa cell lines and their 577. strong inhibitory effect against tubulin polymerization suggest that a combinat[r] ...
22
The Design, Synthesis, and Biological Evaluation of Dimeric Β-Carbolines Based on the Structure of Neokauluamine and the Study of Manzamine A Dimerization Toward Neokauluamine
... interesting biological activities of dimeric β-carboline (25) against various NSCLC cell lines led us to further study its cellular mechanism to induce cell death in H1299 ...
390
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL BENZIMIDAZOLE DERIVATIVES
... From the literature that the benzimidazole functions are quite stable, and have inspired chemists to utilize these stable fragments in bioactive moieties to synthesize new compounds possessing biological ...
7
TOWARDS THE TOTAL SYNTHESIS OF PHORBOXAZOLE A, SYNTHESIS AND BIOLOGICAL EVALUATION OF COUMARIN ANALOGUES AS DNA GYRASE INHIBITORS AND DEVELOPMENT OF NEW SYNTHETIC METHODOLOGIES
... enormous biological activity and the fascinating molecule structure have stimulated synthetic efforts by a number of research groups and seven elegant total syntheses have been reported so ...remarkable ...
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Design, synthesis, and biological evaluation of novel <strong>EF24 </strong>and <strong>EF31 </strong>analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer
... Moreover, biological assays of anti-PC efficacy of D6 indicated effective inhibition of proliferation, as well as the activation of IKK β /NF- κ B pathway, and induction of apoptosis of PC ...
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