Biosynthetic gene clusters
A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters
... called biosynthetic gene clusters ...predicted gene clusters upon further inspection do not show coexpression or do not encode a single functional biosynthetic ...
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MIBiG 2.0: a repository for biosynthetic gene clusters of known function
... Plants, microbes and fungi produce a large variety of spe- cialized metabolites that are often uniquely found in one or a few species. From the dawn of civilization, humans have tapped into this treasure trove for ...
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Heterologous expression of intact biosynthetic gene clusters in Fusarium graminearum
... size gene clusters into the well characterized ...of biosynthetic gene clusters were based on yeast-mediated assembly of PCR-amplified segments into a linearized backbone including an ...
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IMG ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites
... putative biosynthetic gene ...phenazine biosynthetic gene ...phenazine gene cluster (blue box), which were calculated by using a modification of the average nucleotide identity approach ...
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Chromosomal position effect influences the heterologous expression of genes and biosynthetic gene clusters in Streptomyces albus J1074
... and biosynthetic gene clusters is their loca- tion on the chromosome, the so-called ‘chromosomal position ...a gene depending on its chromosomal location. Studies of gene expression in ...
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Antibacterial and anticancer activities of orphan biosynthetic gene clusters from Atlantis II Red Sea brine pool
... Many microbes produce bioactive compounds, known as specialized metabolites, that are not involved in their primary basic activities [8, 9], but rather confer survival advantages to the hosts in their native environment ...
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Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease
... the biosynthetic gene clusters (BGCs) which produce many small molecules, have highlighted the incredible biochemical potential of the signaling molecules encoded by the human ...
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Genetic interrelations in the actinomycin biosynthetic gene clusters of <em>Streptomyces antibioticus</em> IMRU 3720 and <em>Streptomyces chrysomallus</em> ATCC11523, producers of actinomycin X and actinomycin C
... thetic gene clusters prompted to derive a model of formation of the bi-armed acm C gene cluster in ...scacmK gene at the front of the extra arm an imprecise exci- sion event may have removed a ...
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luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria
... To date, LuxR-type regulators have been characterized only from bacteria within the phylum Proteobacteria. All but one of the BGCs identified here are encoded by bacteria in the phylum Proteobacteria. One hit comes from ...
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Appendix A Identification and characterization of biosynthetic gene clusters from halophilic marine fungus Eurotium rubrum
... 4 Institute of Bioinformatics, International Technology Park, Bangalore, 560066 India ;[email protected] 5 Institute of Bioinformatics, International Technology Park, Bangalor[r] ...
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Draft genome sequence of Micromonospora sp. DSW705 and distribution of biosynthetic gene clusters for depsipeptides bearing 4-amino-2,4-pentadienoate in actinomycetes
... Fig. 2 Phylogenetic tree of Micromonospora sp. DSW705 and phylogenetically close type strains showing over 98.5 % similarity to strain DSW705 based on 16S rRNA gene sequences. The accession numbers for 16S rRNA ...
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A Single Biosynthetic Gene Cluster Is Responsible for the Production of Bagremycin Antibiotics and Ferroverdin Iron Chelators
... ABSTRACT Biosynthetic gene clusters (BGCs) are organized groups of genes in- volved in the production of specialized ...the biosynthetic pathway depends on iron ...the biosynthetic ...
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Evolution of the streptomycin and viomycin biosynthetic clusters and resistance genes
... a biosynthetic gene cluster or ...the gene from the streptomycin ...self-resistance gene of another aminoglycoside cluster and arrived in those ...horizontal gene transfer. The ...
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Cloning and analysis of the cypemycin biosynthetic gene cluster
... Indeed, Gram-positive bacteria are known to use diverse types of modified peptides specifically for quorum sensing. This does not exclude a supplementary function, since some lantibiotics have been shown to serve as ...
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Advances in research of the structural gene characteristics of the aflatoxin biosynthetic gene cluster
... structural gene cloning, multiple methods are carried out, such as genetic complementation (aϔlB, aϔlD, aϔlI, ...by gene knockout, gene complementation studies, or enzymatic studies ...structural ...
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Horizontal gene transfer and evolution of antibiotic gene clusters
... streptomycin pathway-specific regulator, strR, has been found in a set of diverse streptomycetes both phenotypically and genetically that previously have already been[r] ...
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The gentle art of gene arrangement: the meaning of gene clusters
... The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2002/3/3/comment/2002 © BioMed Central Ltd (Print ISSN 1465-6906; Online ISSN 1465-6914) With only rare ...
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Analysis of the arginine biosynthetic gene cluster argCJBDFR of Corynebacterium crenatum
... arginine biosynthetic pathway, and further more contribute to the improvement of arginine produc- ...arginine biosynthetic gene sequence and softwares eg. Laser- gene, BPROM, RNAshapes were ...
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The Biosynthetic Gene Cluster for the -Lactam Carbapenem Thienamycin in Streptomyces cattleya
... downstream gene encoded an amino acid region similar to known -LS: proposed to encode an IPNS by Li and coworkers ...pcbAB gene product, an ACVS two of the cosmids shared a hybridizing BamHI band involved ...
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Revised structure of anthelvencin A and characterization of the anthelvencin biosynthetic gene cluster
... involved in anthelvencin biosynthesis, we replaced ant23 by the aac(3)IV resistance cassette 218. following the previously described protocol[r] ...
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