Bis(indolyl) methanes
Cyanoacetic acid promoted an eco expedient synthesis of bis(indolyl)methanes at ambient temperature condition
... To the solution of 15 mole% of cyanoacetic acid in water (20 ml) appropriate aldehyde (2 mmol) and indole (4 mmol) were added and the mixture was stirred at room temperature for the mentioned reaction time (Table I). The ...
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Grape juice Catalysed Synthesis of Bis (Indolyl) Methanes in Aqueous Medium: A Green Approach
... In continuation of our efforts to develop environmentally green protocols for the synthesis of heterocycles, we have presented a neat methodology for the synthesis of bis (indolyl) methanes by ...
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Simple and efficient synthesis of bis(indolyl)methanes by using NiSO4 6H2O
... important Bis(indolyl) methanes ...that Bis(indolyl) methanes are known to increase estrogen metabolism in human beings and hence can be used for the treatment of breast cancer, ...
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Trichloroacetic Acid Mediated Solvent-free Synthesis of Bis(indolyl)methanes Utilizing Grinding Technique
... of bis(indolyl) methanes under solvent free conditions, utilizing grinding technique at room ...of bis(indolyl)methane as the main ...of bis (indolyl)methanes from ...
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Sisal DCT catalyzed rapid and clean synthesis of bis(indolyl)methanes under mild conditions
... Sisal supported 2, 4-dichloro-1, 3, 5-triazine (Sisal-DCT) was found to be an environmentally renewable, inexpensive solid acid catalyst for the electrophilic substitution reaction of indole with carbonyl compounds to ...
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Silica Sodium Carbonate as a Green and Heterogenous Catalyst for the One Pot Solid State Synthesis of Bis(indolyl)methanes
... bis(indolyl)methanes:A mixture of aldehyde (1 mmol), indole (2 mmol) and SSA were grinded in a pestle mortar and continued until the reaction was completed. Progress of the reaction was monitored by TLC ...
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SYNTHETIC APPROACHES FOR BIS (INDOLYL) METHANES
... are bis (indolyl) ...of bis (indolyl) methanes from indoles and carbonyl compounds using protic acids 10 and Lewis acids 11 ...(indolyl) methanes for the first time which ...
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SYNTHESIS AND STUDY OF ANALGESIC, ANTI INFLAMMATORY ACTIVITIES OF BIS (INDOLYL) METHANES (BIMs)
... (indolyl) methanes are found in cruciferous plants and are known to promote beneficial estrogen metabolism and induce apoptosis in human cancer cells 5 ...3-biindolyl methanes on the proliferation ...
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Microwave promoted Zirconium (IV) Chloride as an efficient, environmentally benign and recyclable homogeneous catalytic system to synthesis of bis(indolyl)methanes, in PEG as a solvent
... corresponding bis(indolyl)alkanes, which is the useful class of biologically active organic ...of bis(indolyl)alkane has attracted interest because of their occurrence in various natural ...
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Sulfonylbis(1,4-phenylene)bissulfamic acid (SPSA): Introduction of an efficient and reusable catalyst for the synthesis of bis(indolyl)methanes
... [8]. Bis(indolyl)methanes possessing diverse pharmacological activities such as anticancer [9], antimicrobial [10], anti-oxidant [11], and anti-inflammatory [12] activities; also, these types of ...
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Efficient CeO2 nanoparticles catalysed for Synthesis of heterocyclic Bis(Indolyl) methanes under mild conditions
... nanoparticles were found to be an efficient catalyst in the reaction of indoles with carbonyl compounds to afford the corresponding bis(indolyl)methanes. .The significances of this method are mild ...
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New Green Synthesis and Antineoplastic Activity of Bis (3 Arylimidazolidinyl 1) Methanes
... of bis (3-arylimidazolidinyl-1) methanes 1 - 6 are ...compound, bis(3-phenylimidazolidinyl-1)methane 1 and the monohalogenated derivatives 4-chlorophenyl 3 and 3-bromophenyl 5 showed antineoplastic ...
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Silica supported-boron sulfonic acid: a versatile and reusable catalyst for synthesis of bis(indolyl)methane in solvent free and room temperature conditions
... of bis(indolyl)methane derivatives included reaction of indole with various carbonyl compounds in the presence of different catalyst ...of bis(indolyl)methanesin organic chemistry, chemists ...
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ABSTRACT: In this communication, we report an efficient synthesis of bis-(indolyl)methane derivatives from indole
... Dehydropyrimidiones, Bis(indolyl)methanes and N-alkyl and N-arylimides in Inonic Liquids‖, Journal of the Iranian Chemical Society, ...of Bis- (indolyl)methane using Ethyl Ammonium ...
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Synthetic studies towards the synthesis of Amaryllidaceae Alkaloids: ent-7-deoxy pancratistatin, Pancratistatin and Conduramines
... moreover bis (indolyl) methanes are versatile building blocks for the synthesis so many ...of bis (indolyl) methanes is an important synthetic goal, we have developed a novel ...
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Some bis(dialkylphosphinyl) methanes as solvent extractants
... An extensive review of some of the more important neutral organophosphorus compounds as solvent extractants was given. The compounds included were tri-n-butyl phosphate, TBP, tri-n-octylphosphine oxide, TOPO, tris (2 ...
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1,1 Bis(3' indolyl) 1 (p biphenyl)methane inhibits basal like breast cancer growth in athymic nude mice
... cells in vitro via downregulation of Akt, and it inhibits melanoma tumor growth in vivo [22,23]. In breast cancer, however, one study suggests that PPAR-a activation increases proliferation of both MDA-MB-231 and MCF-7 ...
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Reinforcement Sensitivity Theory of Personality Questionnaires: Structural survey with recommendations
... the BIS, item content was related to habitual behaviours in response to cues of punishment, frustrative non-reward and novel ...and BIS/anxiety; and (b) a lack of sub-components and scales for the BAS, ...
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← Return to Article Details THE INHIBITION OF STEEL CORROSION IN ACIDIC SOLUTIONS BY A NEW SCHIFF BASE
... The effect of temperature on the inhibited acid–metal reaction is very complex, because many changes occur on the metal surface such as rapid etching and desorption of inhibitor and the inhibitor itself may undergo ...
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Activation of Methanes by Doubly Charged Metal Dication Complexes in the Gas Phase
... Comparing the calculated DFT and PEC interaction energies for methane with manganese pyridine dication complex ion the electrostatic energy is drastically overestimated on the potential [r] ...
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