Bisphosphonate therapy
Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report
... Abstract: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of ...
5
Bilateral atypical insufficiency fractures of the proximal tibia and a unilateral distal femoral fracture associated with long term intravenous bisphosphonate therapy: a case report
... of bisphosphonate treatment outweigh the relatively low risk of this rare group of aty- pical ...continuing bisphosphonate therapy, the majority of patients who sustain a fracture go on to make a ...
6
Is bisphosphonate therapy for benign bone disease associated with impaired dental healing? A case controlled study
... and bisphosphonate use, the former study design has a number of ...to bisphosphonate therapy and the outcome of delayed healing and subsequent ONJ, something which cannot be accounted for easily in a ...
10
Osteoclast profile of medication related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis
... Background: The medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy [MRONJ (BP)] is characterized by non-healing exposed bone in the maxillofacial region. The pathogenesis of ...
14
Long Term Outcome of Bisphosphonate Therapy in Patients with Primary Hyperparathyroidism
... term bisphosphonate therapy on BMD, bone fragility fracture and biochemical markers of bone metabolism in patients with ...phosphonate therapy were studied ...phosphonate therapy) BMD T-scores ...
8
Cyclic bisphosphonate therapy reduces pain and improves physical functioning in children with osteogenesis imperfecta
... nitrogen-containing bisphosphonate therapy, which has been shown to decrease bone turnover, improve bone mineral density and reduce fracture rates [14, ...phosphonate therapy is typically initiated ...
7
Oral Bisphosphonate Therapy for Vitamin D Intoxication of the Infant
... IV bisphosphonate therapy is relatively expensive. Thus, we decided to use an oral bisphosphonate. Alendronate sodium offers continuous oral dosing with theoretically less risk to skeletal growth and ...
5
Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy
... This retrospective, observational medical record review was approved by the Colorado Multiple Institutional Review Board. Electronic health records (EHRs) from eight primary care clinics within the University of Colorado ...
6
Bisphosphonate therapy for spinal osteoporosis in Hajdu-Cheney syndrome – new data and literature review
... that bisphosphonate therapy in is essentially em- pirical, opportunities to explore treatment strategies around signaling through NOTCH2 should be consid- ...
7
Genetic Polymorphism of Geranylgeranyl Diphosphate Synthase (GGSP1) Predicts Bone Density Response to Bisphosphonate Therapy in Korean Women
... of bisphosphonate therapy was analyzed according to the ...to bisphosphonate therapy compared with women with other genotypes in GGPS1 -8188 after adjusting for baseline BMD (OR = ...to ...
8
ATypical Metatarsal Fracture in a Patient on Long-Term Bisphosphonate Therapy
... These fractures are substantially difficult to heal with conservative management [17]. The currently-accepted guideline for the treatment of incomplete or complete fractures is operation along with discontinuation of ...
6
Bisphosphonate-Related Osteonecrosis of the Jaws. A Severe Side Effect of Bisphosphonate Therapy
... phosphonate therapy and should be reffered to the dentist to have all dental diseases treated (1, ...periodontal therapy as well as tooth extractions and other oral surgical procedures should be performed ...
5
Intravenous Bisphosphonate Therapy in Children With Osteogenesis Imperfecta
... receiving bisphosphonate therapy (Table ...on therapy were associated with increased activity and moderate to severe trauma (eg, patient 3 while punching a wall and lifting heavy cartons; patient 4 ...
8
Improving Inter Professional Communication among Medical and Dental Providers Treating Bisphosphonate Therapy Patients May Reduce the Risk of Osteonecrosis of the Jaw
... BP therapy in this cohort, and communicate with dental practitioners to improve treatment ...antiresorptive therapy and still have a significant reservoir of BPs in the skeletal ...
8
Short-Term Bisphosphonate Therapy Could Ameliorate Osteonecrosis: A Complication in Childhood Hematologic Malignancies
... We described the cases of two pediatric patients who were on long-term steroid treatment before BMT for hematologic disease and for acute or chronic GVHD. They presented ON of the femoral head and osteoporosis after BMT. ...
6
Clinical role of bisphosphonate therapy
... bone loss in GIOP compared with in PMO, which is primarily a disorder of increased bone resorption. Other explanations include variability in the study patients, who had a range of underlying diseases and were on varying ...
15
Dental Implant Placement in Patients on Bisphosphonate Therapy: a Systematic Review
... of 842. This gives us a better percentage of implant healing with intraoral BPs than with no medication usage in the control group and in the intravenously treated group, which was unreliable (considering that number of ...
12
Current state of orthodontic patients under Bisphosphonate therapy
... Conclusions: Orthodontic tooth movement under bisphosphonate medication is possible, especially in low-risk patients (low dose and short period of intake). But the treatment is still not predictable, especially in ...
6
The association between compliance and persistence with bisphosphonate therapy and fracture risk: A review
... The studies reviewed highlight that compliance and per- sistence levels with bisphosphonates are sub-optimal [17,18] with many discontinuing treatment soon after therapy initiation [19]. A diagnosis of ...
6
Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy
... BP therapy may result in the suppression of bone turn over and confer a predisposition to increased bone fragility, with an increased risk of atypical fractures ...
7