blood eosinophils
Evaluation of exacerbations and blood eosinophils in UK and US COPD populations
... of blood eosino- phil at a single time point may not be sufficient and might require additional follow-up examinations ...persistent blood eo- sinophil count of approximately 400 cells/μL [22, ...of ...
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Blood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis
... five studies provided inconsistent results when comparing the efficacy of ICS-containing regimens and non-ICS regimens/ ICS withdrawal/placebo treatments at reducing exacerbation risk. In the meanwhile, we excluded the ...
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Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients
... Blood eosinophils exert not only a protective but also an inflammatory ...creased blood eosinophil count is a risk factor for coron- ary heart disease [21] and Tanaka M et ...high blood ...
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Relationship between blood eosinophils, clinical characteristics, and mortality in patients with COPD
... ID. Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two ...
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Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids
... baseline eosinophils and treatment was nonsignificant, and the effect of baseline eosinophils was nonsignificant in the FORWARD exacerbation ...baseline blood eosinophil count and ...baseline ...
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Serial blood eosinophils and clinical outcome in patients with chronic obstructive pulmonary disease
... single blood eosinophil measurement might not indicate a stable ...measured blood eosinophils every 3 months over a 1-year period revealed that 65% of COPD patients remained persistently above or ...
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CD40 expression by human peripheral blood eosinophils
... peripheral blood eosinophils, the most preva- lent inflammatory cell type in such type of inflammation, ex- press CD40 and, secondarily to investigate some of the func- tional consequences upon CD40 ...
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Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
... paired blood and spu- tum cell counts, which were obtained from samples collected during the same visit, were ...peripheral blood inflammatory cell counts, smoking history, body mass index, preceding year ...
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Elevated Blood Eosinophils and serum IgE levels as biomarkers in prediction of COPD exacerbation
... of eosinophils, a higher percentage experienced wheezing during a cold and reported sputum of 3 months duration with history of respiratory ...with eosinophils above 2% were current smokers, but the groups ...
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<p>Blood Eosinophilia and Its Stability in Hospitalized COPD Exacerbations are Associated with Lower Risk of All-Cause Mortality</p>
... of blood eosinophils at baseline with all-cause ...of blood eosinophils and all-cause mortality, 241 inpatients who underwent at least three hospitalizations for AECOPD over 5 years and had ...
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Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma
... eral blood eosinophils instead of airway tissue ...the eosinophils affecting ASMC have migrated from peripheral blood into the airway ...of eosinophils and their counter-structures on ...
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Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers?
... FENO, blood eosinophils, total IgE or their combination to rule in or rule out eosinophilic asthma, we chose pragmatic thresholds for each biomarker based on previously published data [4–8], with 2 ...
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Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13
... mouse eosinophils [5] and levels of Siglec-F are up-regulated on peripheral blood eosinophils following acute OVA challenge in wild type (WT) mice ...peripheral blood eosinophils as do ...
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Human eosinophils can express the cytokines tumor necrosis factor alpha and macrophage inflammatory protein 1 alpha
... human eosinophils represent a potential source of TNF-alpha and MIP-1 alpha, that levels of expression of mRNA for both cytokines are high in the blood eosinophils ...
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<p>A case of chronic eosinophilic pneumonia in a patient treated with dupilumab</p>
... in blood eosinophilia was also ...revealed eosinophils alveolitis (60%) while TBB showed fi ndings compatible with chronic eosinophilic pneumonia ...in blood eosinophils count and subsequent ...
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<p>Eosinophil levels predict lung function deterioration in apparently healthy individuals</p>
... between blood eosinophils and lung functions was found, reinforcing that eosinophilia is a major risk factor for lung function decline even in older ...
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Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma
... Analysis of the data was performed using SPSS 19 (IBM Corporation, Armonk, NY, USA). Continuous variables are expressed as mean ± SD or median (interquartile range) for non-normal variables when appropriate, and ...
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Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma
... asthma, blood eosinophil counts are about 25% higher at 0400 h than at 1600 h ...in blood eosinophils and lung function appear to fall into a con- tinuous range, suggesting that day/night variations ...
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Patient profiles and clinical utility of mepolizumab in severe eosinophilic asthma
... baseline blood eosinophil count and magnitude of treatment response with mepo- lizumab was identified, with a threshold baseline blood eosinophil count of 150 cells/µL predictive of significant treatment ...
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Pathogenesis of eosinophilic chronic rhinosinusitis
... circulatory eosinophils and tis- sue eosinophils are prominent features of ...of eosinophils in bone marrow in response to cytokine activation, and following an appropriate stimulus, they are ...
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