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bluetongue virus (BTV)

Recovery of Infectious Bluetongue Virus from RNA

Recovery of Infectious Bluetongue Virus from RNA

... Bluetongue virus (BTV) is transmitted between ruminant hosts by several species of biting midges of the genus Culi- coides, which determine its geographic ...The virus particle has a layered ...

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Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence

Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence

... Bluetongue virus (BTV) is the causative agent of bluetongue, a major infectious disease of ruminants with serious consequences to both animal health and the ...the virus and the ...by ...

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Vesicular stomatitis virus replicon expressing the VP2 outer capsid protein of bluetongue virus serotype 8 induces complete protection of sheep against challenge infection

Vesicular stomatitis virus replicon expressing the VP2 outer capsid protein of bluetongue virus serotype 8 induces complete protection of sheep against challenge infection

... Bluetongue virus (BTV) is an arthropod-borne pathogen that causes an often fatal, hemorrhagic disease in ...inactivated virus vaccines, the epidemic caused significant economic losses not only from ...

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Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)

Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)

... Background: Bluetongue virus (BTV) and African horse sickness virus (AHSV) are distinct arthropod borne virus species in the genus Orbivirus ( Reoviridae family), causing the notifiable ...

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Reassortment of bluetongue virus vaccine serotypes in cattle

Reassortment of bluetongue virus vaccine serotypes in cattle

... the virus from the infected ...9) Bluetongue is primarily a disease of sheep in South Africa, while cattle and goats are mostly subclinically ...of bluetongue virus in cattle lasts much longer ...

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Experimental bluetongue virus superinfection in calves previously immunized with bluetongue virus serotype 8

Experimental bluetongue virus superinfection in calves previously immunized with bluetongue virus serotype 8

... with bluetongue virus serotype 1 (BTV1) was evaluated on two groups of four ...between virus strains, genetic reassortment and cross-protection were considered as mechanisms to explain the clini- cal ...

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Synthesis and antiviral activity of 1,3,4 oxadiazolyl selenopheno[2,3 d]pyrimidines as novel Bluetongue virus inhibitors

Synthesis and antiviral activity of 1,3,4 oxadiazolyl selenopheno[2,3 d]pyrimidines as novel Bluetongue virus inhibitors

... against Bluetongue Virus, a series of novel 1,3,4- oxadiazolyl selenopheno[2,3-d]pyrimidines bearing a choice of aromatic moieties with different substituents were synthesized in five steps reaction ...

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Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence

Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence

... Bluetongue virus (BTV) is the causative agent of bluetongue, a major infectious disease of ruminants with serious consequences to both animal health and the ...the virus and the ...by ...

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Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection

Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection

... by bluetongue virus (BTV), an arbovirus transmitted by ...assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental frame- ...same virus ...

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Genomic analysis of bluetongue virus episystems in Australia and Indonesia

Genomic analysis of bluetongue virus episystems in Australia and Indonesia

... Bluetongue virus episystems in Australia and Indonesia Our genetic analyses of the Australian and Indonesian BTV viruses available to date indicate that all sampled BTVs in Australia have their origins in ...

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Determinants of Bluetongue Virus Virulence in Murine Models of Disease

Determinants of Bluetongue Virus Virulence in Murine Models of Disease

... “bluetongue virus” are generally referred to as single entities, but they represent a group of diseases induced by a variety of genotypically and serotypically related ...the virus serotype/strain, ...

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Intragenic Recombination as a Mechanism of Genetic Diversity in Bluetongue Virus

Intragenic Recombination as a Mechanism of Genetic Diversity in Bluetongue Virus

... Bluetongue virus (BTV), the pathogen of BT, belongs to the Orbivirus genus of the Reoviridae family ...The virus has a segmented double-stranded RNA (dsRNA) genome that is packaged in a nonenveloped, ...

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Membrane Organization of Bluetongue Virus Nonstructural Glycoprotein NS3

Membrane Organization of Bluetongue Virus Nonstructural Glycoprotein NS3

... Bluetongue virus (BTV), a member of the Orbivirus genus, family Reoviridae, synthesizes four nonstructural proteins in infected cells (NS1, NS2, NS3, and NS3A) in addition to the seven structural proteins ...

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Seroprevalence of Bluetongue Virus Antibody in Ruminants from Grenada

Seroprevalence of Bluetongue Virus Antibody in Ruminants from Grenada

... The aim of the present study was to estimate the seroprevalence of antibodies to bluetongue virus (BTV) among domestic ruminants of Grenada. Sera samples from cattle (133), goat (314) and sheep (481) were ...

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Cloning of the bluetongue virus L3 gene.

Cloning of the bluetongue virus L3 gene.

... 754 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The genes of the bluetongue virus BTV serotype 17 have been cloned into pBR322 by tailing both strands of the double[r] ...

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Characterization and modification of the carboxy-terminal sequences of bluetongue virus type 10 NS1 protein in relation to tubule formation and location of an antigenic epitope in the vicinity of the carboxy terminus of the protein.

Characterization and modification of the carboxy-terminal sequences of bluetongue virus type 10 NS1 protein in relation to tubule formation and location of an antigenic epitope in the vicinity of the carboxy terminus of the protein.

... Bluetongue virus produces large numbers of tubules during ...of bluetongue virus serotype 10 NS1 has been generated and expressed in insect cells in order to identify the carboxy-terminal ...

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Studies on the Topography of Reovirus and Bluetongue Virus Capsid Proteins

Studies on the Topography of Reovirus and Bluetongue Virus Capsid Proteins

... Lambda 2 is the major surface component of the reovirus core, and proteins 1, 3, and 4 appear to be the outer components of the bluetongue virus subviral particle.. Reovirus and bluetong[r] ...

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Bluetongue Virus Entry into Cells

Bluetongue Virus Entry into Cells

... The uncoating of BTV by losing the outer capsid proteins was reported to be essential for triggering the transcriptional competence of the core (15, 16, 45). Recent high-resolution cryo-EM analysis and ...

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Cellular phosphoinositides and the maturation of bluetongue virus, a non enveloped capsid virus

Cellular phosphoinositides and the maturation of bluetongue virus, a non enveloped capsid virus

... glycosylated. Upon infection, the core particles become active, synthesizing ten capped single-stranded RNA tran- scripts (ssRNAs) which extrude through the capsid pores into the cytoplasm. The newly synthesized core ...

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Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress

Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress

... both virus aggregates and single virion particles retain an association with the cortical layer of the cytoskeleton following cell ...only virus-coded glycoprotein of BTV, interacts with VP2 as well as ...

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