BM-MSC
BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
... of BM-MSCs induced by irradiation reduced functional and viable MSCs in bone marrow ...in BM-MSCs after irradiation. In this study, we found that BM-MSC-derived exosomes could partially rescue ...
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BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression
... transduction with the pGC-GFP/Luc vector (gift of A. Kung, Dana-Farber Cancer Institute). Patients presented with median age of 69 years (range, 60–72 years) and were diagnosed with either MM, MGUS, or smoldering MM ...
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Mesenchymal stem cells promote a primitive phenotype CD34+c-kit+ in human cord blood-derived hematopoietic stem cells during ex vivo expansion
... 16]. BM-MSC have thus been included in HSC expansion strategies and niche studies for maintaining HSC biological characteristics ex ...if BM-MSC-secreted cytokines are sufficient to maintain ...
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High-throughput immunophenotypic characterization of bone marrow- and cord blood-derived mesenchymal stromal cells reveals common and differentially expressed markers: identification of angiotensin-converting enzyme (CD143) as a marker differentially expressed between adult and perinatal tissue sources
... for MSC, an important outcome of the present study was to find the existence of markers differ- entially expressed among ...that MSC from different origins may have differences in marker expression and ...
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Bovine fetal mesenchymal stem cells exert antiproliferative effect against mastitis causing pathogen Staphylococcus aureus
... In contrast to bBD4A and NK1, the expression of two previously reported MSC-derived AP, CATHL2 and HEP was not detected in BM-MSC or AT-MSC. These results provide evidence on the potential ...
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A crosslinked collagen membrane versus a non-crosslinked bilayer collagen membrane for supporting osteogenic functions of human bone marrow-multipotent stromal cells
... human BM aspirate samples containing rare MSC populations as well as culture-expanded human BM-MSCs and tested their functional behaviour using various molecular and functional ...visualise ...
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Cigarette smoke challenges bone marrow mesenchymal stem cell capacities in guinea pig
... mises BM-MSCs functional capabilities severely affecting their proliferation, homing and repair ...produces BM-MSC ...of BM-MSCs after in vivo lung administration and by studying in vitro ...
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Update on mesenchymal stem cell based therapy in lupus and scleroderma
... of BM-MSC transplantation in SLE and its efficacy com- pared with conventional CY treatment has been investi- gated in MRL/lpr mice as an SLE mouse model [43, ...44]. MSC injection resulted in a ...
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Bone marrow-derived from the human femoral shaft as a new source of mesenchymal stem/stromal cells: an alternative cell material for banking and clinical transplantation
... of BM-MSC isolation from the iliac crest have been ...ready-to-use MSC fraction ...of MSC by using the whole bone marrow seeding technique, the method recently recommended for a large scale of ...
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Mesenchymal stem cells, autoimmunity and rheumatoid arthritis.
... allogeneic MSC. The Using of autologous MSC did not seem to improve SLE disease course despite an increase of proportion of peripheral blood ...86 MSC extracted from SLE patients grew slower in cul- ...
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Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
... allogenic BM-MSC and AD-MSC administration compared with the infarct ...after BM-MSC administration ...or BM-MSC 24 h after transitory ischemia in mice ...
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Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review
... naïve MSC targeting cancers such as hepatic, gastric and lung are rare, ren- dering any attempt to evaluate the MSC performance against the latter ...of MSC: tumor interactions, at the same time ...
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Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC)
... The expression of Netrins was first characterized in Wharton’s jelly umbilical cord sections (Fig. 1a). We detected preferentially the presence of Netrin-1 but not of Netrin-4. These results were corroborated by qPCR ...
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Transplantation of bone marrow mesenchymal stromal cells attenuates liver fibrosis in mice by regulating macrophage subtypes
... of BM-MSCs and macrophage polarization with the expression of associated matrix metalloproteinases (MMPs) in a liver fibrosis ...of BM-MSCs on liver fibrosis in mice and investigated the impact of ...
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Promoting the expansion and function of human corneal endothelial cells with an orbital adipose-derived stem cell-conditioned medium
... Allophycocyanin; BM: Basal culture medium; BM-MSC: Bone marrow-derived mesenchymal stem cell; CCK-8: Cell counting kit-8; CE: Corneal endothelium; CEC: Corneal endothelial cell; CFSE: ...
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
... Although numerous studies have shown the successful chondrogenic induction of WJ-MSC in 3D scaffolds, our work demonstrated chondrogenic differentiation of WJ- MSC without adding growth factors. Once seeded ...
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Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model
... and BM-MSCs. A. hES-MSCs and BM-MSCs were grown in the 8-well chamber slides coated with ...and BM-MSCs were fixed with 4% paraformaldehyde, and then immunostained for TJ proteins CLN-5, ZO-1 and ...
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Stem cell therapy for diabetic foot ulcers: a review of preclinical and clinical research
... G-CSF is a cytokine that stimulates bone marrow to mobilize endothelial progenitor cells (EPC), increasing the number of available EPC for healing the DFU; G-CSF is found in wound tissue after acute injury [106]. In ...
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miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC- like cells via NF-κB p65 activation
... A large number of studies have demonstrated that miR-155-5p plays a multifunctional role in human cancer cells by regulating many target genes. Several research groups have reported that miR-155-5p acts as an oncomiR by ...
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Protein synthesis and secretion in human mesenchymal cells derived from bone marrow, adipose tissue and Wharton’s jelly
... tissue-derived MSC; bFGF: Basic fibroblast growth factor; BM-MSC: Bone marrow-derived MSC; DMEM: Dulbecco ’ s modified Eagle media; EGF: Endothelial growth factor; FBS: Fetal bovine serum; ...
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