bone and soft tissue sarcomas
Review Article The prognostic value of ezrin expression in bone and soft tissue sarcomas: a meta-analysis
... Generally, sarcomas are a heterogeneous neo- plasms that can be grouped into two types: soft tissue sarcoma (STS) and primary bone sarco- ma (BS) ...Primary bone sarcomas mainly ...
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Review Article Correlation of ezrin expression level and clinical significance for patients with bone and soft tissue sarcomas: a meta-analysis
... various human tumors, such as prostate can- cer, colorectal cancer, melanoma and ovarian cancer [9-11]. However, the prognostic value of Ezrin expression in osteosarcoma patients’ sur- vival or the clinical features ...
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Development of Multi-disciplinary Approach for Bone and Soft-tissue Sarcomas in Japan
... extremity bone and soft- tissue sarcomas are basically consisted of tumor wide resection and a variety of reconstructive ...of bone and soft-tissue tumors including ...
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Feasibility and efficacy of gemcitabine and docetaxel combination chemotherapy for bone and soft tissue sarcomas: multi institutional retrospective analysis of 134 patients
... and soft tissue sarcomas (BSTS) are very rare ma- lignant ...the Bone and Soft Tissue Tumor Registry reported by the Musculoskeletal Tumor Committee of the Japanese Orthopaedic ...
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Prognostic value of IGF-1R expression in bone and soft tissue sarcomas: a meta-analysis
... 4. Borinstein SC, Barkauskas DA, Krailo M, et al. Investigation of the insulin- like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children’s Oncology Group. Cancer. ...
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A phase II study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcomas
... this, the patients tolerated the study regimen well. While interpretation of our results is limited by a small number of patients and comparison to historical controls, of the evaluable patients at our RP2D, PFS was ...
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Population-based Aarhus Sarcoma Registry: validity, completeness of registration, and incidence of bone and soft tissue sarcomas in western Denmark
... In Denmark there is a unique opportunity to validate data on the individual level. Further, use of clinical databases can be extended by unambiguous linkage of data with other Danish population-based data sources in ...
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The Danish Sarcoma Database
... all bone and soft tissue sarcomas of the musculoskeletal system in Denmark, includ- ing the trunk ...roperitoneal sarcomas and sarcomas of the neck and face has been centralized ...
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Sarcomas in hereditary retinoblastoma
... both bone and STS in hereditary Rb patients, structural alterations of the RB1 gene are well documen- ted in primary bone sarcomas [33] and soft tissue sarco- mas ...the bone and ...
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Treating metastatic soft-tissue or bone sarcomas – potential role of ridaforolimus
... advanced bone and soft tissue sarcomas using ridaforolimus ...primary bone sarcomas, leiomyosarcomas, liposarcomas, and other soft tissue ...
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UK guidelines for the management of soft tissue sarcomas
... to soft tis- sue sarcomas arising from limbs and trunk and although, where appropriate, specific guidance is given according to histological subtype it is recognised that some tumours, for example, Ewing ...
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Analysis of surgical and oncological outcome in internal and external hemipelvectomy in 34 patients above the age of 65 years at a mean follow up of 56 months
... primary bone or soft tissue sarcomas, bony me- tastases or benign bony lesions in the pelvic region were considered eligible for the ...
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A Study on Limb Salvage in Extremity Soft Tissue Sarcomas
... adipose tissue in tumours whose fatty component may not be appreciated on plain ...the soft tissue mass and distinguishing the mass from adjacent structures, especially the vascular ...bundle. ...
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Trabectedin for advanced soft tissue sarcomas: optimizing use
... are classified into five different types: well-differentiated, myxoid, round cell, pleomorphic, and de-differentiated. Myxoid liposarcomas account for 40% of liposarcomas and almost 10% of all adult ...
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Response to anti-PD1 therapy with nivolumab in metastatic sarcomas
... of soft tissue sarcomas, has been correlated with a poorer prognosis and more aggressive disease ...advanced soft tissue or bone sarcoma who received the PD-1 antibody nivolumab ...
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Targeted therapy for soft tissue sarcomas in adolescents and young adults
... Therapy with monoclonal antibodies, such as alemtuzumab (CD52), trastuzumab (HER2), brentuximab vedotin (CD30), rituximab (CD20), and blinatumomab (CD19 and CD3), has revolutionized the treatment of many cancers. IGF-1R ...
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A review of soft-tissue sarcomas: translation of biological advances into treatment measures
... tumor site-specific, but prognoses are also linked to primary tumor location. Standard of care depends on primary tumor site and the age of the patient, but can include surgery, radia- tion, and chemotherapy. RMS ...
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Expression of heparanase in soft tissue sarcomas of adults
... of sarcomas constitutes approximately 1% in adults and up to 12% in children of all malignan- ...have soft tissue origins while the rest originate in the ...bone. Soft tissue ...
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MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas
... of bone sarcomas including Ewing’s and ...different soft tissue sarcoma subtypes that have unique molecular and biological ...of soft tissue sarcoma in adults, accounting for ...
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New drugs and combinations for the treatment of soft-tissue sarcoma: a review
... Abstract: Sarcomas are a heterogeneous group of solid tumors arising from either soft tissues or bone, accounting for approximately 1% of all cancers in ...adult soft-tissue ...
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