Bone, cartilage
Original Article An investigation over the impact of conventional Chinese bone setting to cartilage and the VEGF expression in cartilage cells in rats with knee osteoarthritis disease
... The animals were divided to four groups ran- domly: 1) Naïve, 2) Disease group (rats were induced with the model disease for 6 weeks, followed with no treatment), 3) Setting group, the rats were induced with the disease ...
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Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis
... cortical bone defects are more likely to have knee pain in the presence of radiographic OA ...knee cartilage defects alon e were significantly associated with knee pain in a dose-response fashion in a ...
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Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis
... articular cartilage in similar experimental models of OA ...the cartilage layer, without integrating infor- mation from the pre-articular subchondral bone in response to the surgically-induced joint ...
14
Original Article Experimental study of biologically active icariin combined with a porous PLGA/TCP scaffold to repair cartilage and subchondral bone in articular cartilage defect in rabbits
... Articular cartilage defect is a common clinical disease and is mainly caused by trauma, inflam- mation, or a tumor, with pathological cartil- age loss or ...of cartilage to be repaired is still ...the ...
9
Cartilage to bone transitions in health and disease
... endochondral bone growth defect with an expanded hypertrophic chondrocyte zone which was not attributable to increased chondrocyte proliferation, increased proteoglycan turnover and increased trabecular ...
12
CD45lowCD271high Cell Prevalence in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative Therapy
... in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative ...of Bone and Joint Surgery - American Volume, 99 ...
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Assessment of Cartilage Strip and Bone Cement in Ossiculoplasty
... Currently, many materials are utilized in ossiculoplasty. The advantages of use of autologous material (cartilage, ossicles or bone cortex) are easy and cheap to be harvested from the patient. In a ...
7
Piezoelectric smart biomaterials for bone and cartilage tissue engineering
... Tissues like bone and cartilage are remodeled dynamically for their functional requirements by signaling pathways. The signals are controlled by the cells and extracellular matrix and transmitted through an ...
11
Use of Mesenchymal Stem Cells to Grow Cartilage and Bone
... of bone cells while being encapsulated by hydrogels was conducted with polymer networks, which could simulate vari- ous conditions where the stem cells grow ...new cartilage involved initiat- ing ...
5
Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface
... of cartilage, but also stimulated the reconstruction of subchondral bone in ...subchondral bone regeneration as compared to TCP scaffolds, gold standard bio-ceramic scaffolds for bone ...
16
Cartilage specific RBPjκ dependent and independent Notch signals regulate cartilage and bone development
... whether cartilage and bone formation are regulated via RBPj -dependent or -independent Notch signaling ...during cartilage and bone development we generated and compared general Notch ...
15
High resolution MRI imaging at 9 4 Tesla of the osteochondral unit in a translational model of articular cartilage repair
... subchondral bone, as described by Orth et ...subchondral bone cysts were observed while in five defects (26%) intralesional osteophytes were ...subchondral bone cysts were detected in 17 out of 38 ...
12
Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat
... MMP-13 activity as well as RANKL-mediated osteoclas- togenesis and at a range of concentrations (Figs. 1, 2 and 3, Table 2, and Additional file 1: Figs. S3–S18). The drug IMMD-0354 (Institute for Medicinal Molecular ...
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Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA
... subchondral bone are considered critical for the health of the articular cartilage and for normal joint physiology [4, ...subchondral bone pathophysi- ology that frequently accompany cartilage ...
16
Building the backbone: the development and evolution of vertebral patterning
... of bone that forms around and eventually replaces the cartilage template (Peignoux-Deville et ...calcified cartilage and arch bone is important, as it allows for comparison with ...the ...
12
Articular cartilage mineralization in osteoarthritis of the hip
... the cartilage was trimmed and cleaned with a clean blade, removing bone debris from the sawing procedure to avoid contamination with bone dust from surgery or ...of cartilage specimens were ...
8
Effect of celastrol on bone structure and mechanics in arthritic rats
... Objective Rheumatoid arthritis (RA) is characterised by chronic inflammation leading to articular bone and cartilage damage. Despite recent progress in RA management, adverse effects, lack of efficacy and ...
11
Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice
... consistent with those seen in type II collagen-induced arthritis in most joints, with scores ranging from minimal to severe. Microscopic alteration included infil- tration of synovium and periarticular tissue with ...
10
New developments in osteoarthritis Sex differences in magnetic resonance imaging based biomarkers and in those of joint metabolism
... of cartilage loss than men [22,23], whereas men may have a higher rate of cartilage loss than women in studies in the US ...of cartilage volume loss than men in all knee compartments, although only ...
8
Childhood and adulthood determinants of knee joint health in young adults
... A strength of this thesis was the use of 25-year prospective data with physical activity and performance measures at baseline and tibial cartilage volume/bone area after 25 years. This thesis has several ...
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