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Bone Repair

An endochondral ossification approach to early stage bone repair: Use of tissue engineered hypertrophic cartilage constructs as primordial templates for weight bearing bone repair

An endochondral ossification approach to early stage bone repair: Use of tissue engineered hypertrophic cartilage constructs as primordial templates for weight bearing bone repair

... Mimicking endochondral ossification to engineer constructs offers a novel solution to overcoming the problems associated with poor vascularisation in bone repair. This can be achieved by harnessing the ...

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An evaluation of poly DL-Lactide-co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit

An evaluation of poly DL-Lactide-co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit

... The repair of osseous defects has also been shown to be further enhanced when bone derived growth factors are incorporated into a delivery system (Damien et al, 1990; Lucas et al, 1990; Moore et al, 1990; ...

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Osteoblast derived VEGF regulates osteoblast differentiation and bone formation during bone repair

Osteoblast derived VEGF regulates osteoblast differentiation and bone formation during bone repair

... decreased bone mass and bone vas- cularity, possibly leading to osteoporosis (24, 31, ...in bone may be of value in cases of defective bone healing and to promote bone ...a ...

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Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo

Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo

... facilitate bone growth in vivo, we surgically created cranial bone defects in SD ...new bone-like tissue determined by micro-CT, combined with histological examination and immunohistochemical ...

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Composite scaffolds of mesoporous bioactive glass and polyamide for bone repair

Composite scaffolds of mesoporous bioactive glass and polyamide for bone repair

... The study was approved by the Laboratory Animal Center of Shanghai University of Traditional Chinese Medi- cine (Shanghai, China). A study in a rabbit femur cavity defect model was carried out to investigate the efficacy ...

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Evaluation of a biopolymer matrix for cell based bone repair

Evaluation of a biopolymer matrix for cell based bone repair

... for bone repair has been investigated as a collagen matrix for primary dural ...promote repair by supporting neovascularization, growth and differentiation of ...

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Effects of chitosan on dental bone repair

Effects of chitosan on dental bone repair

... Objectives: Bone defects following tumor re- section and osteolysis due to dental and bone lesions and periodentium tissue disorders are serious ...socket repair after dental ...the repair ...

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Mesenchymal stem cells overexpressing Ihh promote bone repair

Mesenchymal stem cells overexpressing Ihh promote bone repair

... We next performed histological study to further under- stand how EGFP + Ihh + MSCs/HA implants promote bone repair in this model. Specifically, at 4 weeks follow- ing implantation, histological study found ...

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Characterization of bone repair in rat femur after treatment with calcium phosphate cement and autogenous bone graft

Characterization of bone repair in rat femur after treatment with calcium phosphate cement and autogenous bone graft

... new bone tissue in the interface ...human bone marrow cells during in vitro culture on calcium phos- phate ceramics, showing that the cells populated the pores of the ...

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Translation of remote control regenerative technologies for bone repair

Translation of remote control regenerative technologies for bone repair

... clipped and prepared using a chlorhexidine gluconate solution BP 20% Hibiscrub Veterinary,.. Schering-Plough, UK followed by an alcohol gel before surgical drapes were applied.[r] ...

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Translation of remote control regenerative technologies for bone repair

Translation of remote control regenerative technologies for bone repair

... Controlled Differentiation of Human Bone Marrow Stromal Cells Using Magnetic Nanoparticle Technology.. Concise Review: The Surface Markers and Identity of Human Mesenchymal Stem Cells.[r] ...

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Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

... Drugs are the most controllable factor because their impact on bone healing can be taken into account with respect to their choice and dosage. This especially applies to drugs administered due to an injury, such ...

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Fatigue failure of osteocyte cellular processes: implications for the repair of bone

Fatigue failure of osteocyte cellular processes: implications for the repair of bone

... a bone may identify the presence of a microcrack and provides findings that fit with our group’s hypothesis that the rupture of osteocyte cell processes can cause the release biochemical signals necessary for the ...

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Scaffolds for the repair of bone defects in clinical studies: a systematic review

Scaffolds for the repair of bone defects in clinical studies: a systematic review

... of bone-marrow-derived mononuclear cells (BMMNCs) plus interconnected porous calcium hydroxyapatite (IP- CHA) on early bone repair for osteonecrosis of the fem- oral head with those of without BMMNCs ...

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Separate and combined effects of hypobaric hypoxia and hindlimb suspension on skeletal homeostasis and hematopoiesis in mice

<p>Separate and combined effects of hypobaric hypoxia and hindlimb suspension on skeletal homeostasis and hematopoiesis in mice</p>

... a bone repair study in which animals bearing a drill-hole bone defect were exposed to the same experimental set-up combining suspen- sion and delayed ...a bone catabolic effect of EPO is ...

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Effect of Poloxamer 407 as a carrier vehicle on rotator cuff healing in a rat model

Effect of Poloxamer 407 as a carrier vehicle on rotator cuff healing in a rat model

... Specimens were fixed overnight in 4% paraformaldehyde and decalcified in 14% ethylenediamine tetraacetic acid. Specimens were embedded in paraffin, sectioned at 5 μm, and dried for 1 h at 60°C, after which they were ...

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One Stage Repair and Reconstruction of Craniomaxillofacial Bone Defects

One Stage Repair and Reconstruction of Craniomaxillofacial Bone Defects

... craniomaxillofacial repair and reconstruction are to prevent the incidence of postoperative complica- tions and to restore the craniofacial features and function [1,2,10], in which the restoration of features and ...

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The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect

The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect

... on bone regeneration have been widely investigated in the past ...inhibit bone loss, improve bone quality, and promote proliferation and mineralization of osteoblasts [20, ...on bone defect ...

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Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

... in bone we recently generated mice bearing a homozygous Nf1 inactivation in the embryonic limb and in the cranial ...force, bone fracture and the expected pseudarthrosis never occur ...of bone ...

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Study on Hydroxyapatite Nano Reinforced by Ultrasonic Preparation

Study on Hydroxyapatite Nano Reinforced by Ultrasonic Preparation

... The synthetic bone graft material to a certain extent, can reach autologous and allogeneic bone repair effect, and also to avoid infections and bone finite sources such problems, therefo[r] ...

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