Brain and cell death
Lineage specific cell death in postembryonic brain development of Drosophila
... programmed cell death in these lineages? For the PC lineage, there is some indication that the total clone size is reduced by approximately half in en loss-of-function mutants, compared with wild type ...
10
Neurogenesis, cell death and regeneration in the adult gymnotiform brain
... of cell death in postembryonic development Until recently, cell death had been thought to be absent from the brain of fish in stages beyond embryogenesis (Fox and Richardson, 1982; ...
12
Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain
... neural cell damage and death (for review see reference ...excitotoxic brain le- sions ...neural cell death, demonstrating the usefulness of such methodological tools for designing ...
9
Neuronal programmed cell death induces glial cell division in the adult Drosophila brain
... glial cell division suggests that the former might induce the ...If cell death signalling induces cell division, as observed in the imaginal wing discs, this would be expected to increase the ...
9
Neonatal Hypoxic-Ischemic Brain Injury: Apoptotic and Non-Apoptotic Cell Death
... proteins are required for initiation, vesicle elongation, autophagosome maturation, lysosome fusion, and degradation. Targeting the autophagic machinery could have significant impact in protecting the neonatal ...
6
Bench to bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury
... of brain injury and are competitive inhibitors designed according to specific amino acid target sequences at the cleavage site of the respective caspase substrates (reviewed in [68, ...reduce brain tissue ...
10
Control of adult neurogenesis by programmed cell death in the mammalian brain
... of brain homeostasis, and accumulating evidence suggests that IGF-1 regulates adult neurogenesis via modulation of the number of newly generated neurons and synapto- genic outputs [53, ...the brain ...
20
Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease
... altered brain endothelial cell releases factors that are injurious or toxic to neurons ...neuronal cell death in AD is derived from studies where direct co-culture of AD microvessels with ...
12
The Interferon-Stimulated Gene Ifi27l2a Restricts West Nile Virus Infection and Pathogenesis in a Cell-Type- and Region-Specific Manner
... PFU/g) were embedded in Optimal Cutting Temperature medium (OTC; Tissue-Tek), frozen at ⫺ 80°C, and sectioned in 10- m-thick slices on a Microm HM505N cryostat on positively charged slides (Globe Scientific; 1358W). ...
16
POTENTIAL THERAPEUTIC EFFECT OF ZIKA VIRUS IN GLIOBLASTOMA TREATMENT
... for brain cells along with their ability to induce neural cell death, the hypothesis formulated by the current contribution was that this agent would cause cell death in glioblastomas ...
6
Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice
... Traumatic brain injury is currently still lacking a specific pharmacological therapy designed to avoid induction of secondary brain injuries and delayed neuronal cell death ...ondary ...
11
Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap
... neuronal cell death (reviewed in Fortini and Bonini, ...in cell culture, the withdrawal of these factors or blocking their signal transduction pathways leads to cell death (Barres et ...
10
Brain death, the determination of brain death, and member guidance for brain death accommodation requestsAAN position statement
... severely brain-injured patients may encounter requests by loved ones and lawful patient surrogates to delay or prohibit discontinuation of organ-sustaining technology once an individual has been de- termined to be ...
10
Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells
... generate hypotheses and to suggest directions for further phenotypic analyses. We identified six gene networks con- taining genes mainly related to the functional categories "cancer", "cell ...
17
A multiscale analysis of drug transport and response for a multiphase tumor model
... The efficacy of a particular drug is highly dependent on its ability to reach proliferating cells in sufficient quantity to bring about cell damage and a reduction in tumour size (Jain (1989)). This transport is ...
41
Delayed Inflammatory and Cell Death Responses Are Associated with Reduced Pathogenicity in Lujo Virus-Infected Cynomolgus Macaques
... response. Cell type enrichment analysis suggested that host response induction delay and an LUJV-specific profile are due to a different proportion of natural killer cells responding in LUJV infection than that in ...
10
Remarkable changes in the choice of timing to discuss organ donation with the relatives of a patient: a study in 228 organ donations in 20 years
... Our study has some limitations. First, the study was per- formed in a single centre, and data were obtained through a retrospective review of medical charts. How- ever, our hospital is one of the largest university ...
8
Brain Death Determination in the Newborn
... Coker SB, Dillehay GL: Radionuclide cerebral imaging for confirmation of brain death in children: The significance of dural sinus activity. Drake B, Ashwal 5, Schneider 5: Determination [r] ...
7
Determining brain death in adults
... Disadvantages. l ~ Transcranial Doppler ultrasonography requires considerable practice and skill. Somatosensory evoked potentials. Median nerve stimulation is per- formed on bo[r] ...
10
Brain Death
... Recently there have been published criteria of brain death, which do not include the electroencepha- logram.12 It is certainly true that those patients meet- ing the criteria[r] ...
5