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brain injury experimental model

Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury

Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury

... and experimental medium was exchanged for new experimental medium in those plates belonging to the positive control ...the experimental groups dexmedetomidine (Precedex ® 100 μg/ml Dexmedetomidine, ...

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A mathematical model of neuroinflammation in severe clinical traumatic brain injury

A mathematical model of neuroinflammation in severe clinical traumatic brain injury

... our model, microglia sub- types and tissue damage are qualitatively projected with arbitrary units rather than quantified by cell count or tissue ...the brain following ...Although model parameters ...

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Propofol: neuroprotection in an in vitro model of traumatic brain injury

Propofol: neuroprotection in an in vitro model of traumatic brain injury

... in experimental models using whole living animals with all present systemic variables, which are absent in our model of ...of brain injury was significantly shorter than the three-day period ...

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Functional Alterations in the Amygdala Following Traumatic Brain injury

Functional Alterations in the Amygdala Following Traumatic Brain injury

... technique, experimental time point, injury models, and animal strains ...the brain that result in mTBI and a variety of other environmental ...animal brain injury protocols are simply ...

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The effect of traumatic brain injury in experimental models of Alzheimer’s disease

The effect of traumatic brain injury in experimental models of Alzheimer’s disease

... mouse model of AD (Simard et ...the brain due to injury-induced inflammation may phagocytose existing Aβ plaques leading to an overall reduction in plaque load in 6-month-old APP/PS1 ...

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Panax Ginseng Regulates Brain Monoamines in Lipopolysaccharide Induced Experimental Brain Injury

Panax Ginseng Regulates Brain Monoamines in Lipopolysaccharide Induced Experimental Brain Injury

... The slides were examined at 40× magnification using fluorescence microscope (Leica Microsystems, CMS GM b H, Wetzlar, Germany. Model DM 2500) and power Max. 160 W. equipped with an excitation filter of 549 nm and ...

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Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size

Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size

... MCAo model did not result in maximal corti- cal damage in any of the treatment groups (Figure 2), which argues against this ...affect brain injury, we also repeated MCAo and all treat- ments under ...

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Experimental MR study of cerebral radiation injury: quantitative T2 changes over time and histopathologic correlation

Experimental MR study of cerebral radiation injury: quantitative T2 changes over time and histopathologic correlation

... the brain, using diffusion-weighted ...imental model of regional cerebral ischemia; they found a correlation between both T2 relax- ation time and diffusion-weighted images after 6 to 8 hours after a ...

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Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury

Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury

... The experimental model of midline fluid percussion offers the opportunity to examine the diffuse injured brain in the absence of contusion and ...a model of circuit disruption rather than ...

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Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury.

Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury.

... head injury (CHI) is the leading cause of mortality and persisting neurological impairment in young people in industrialized countries ...of brain injury are mediated in large part by a profound ...

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Addressing the needs of traumatic brain injury with clinical proteomics

Addressing the needs of traumatic brain injury with clinical proteomics

... or injury factors a simple experimental model can facilitate a targeted screen cir- cumventing secondary, less disease-specific ...scientific experimental model design follows con- ...

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Brain Injury and Inflammation and Placental Inflammation in Response to Repetitive Umbilical Cord Occlusions in the Near Term Ovine Fetus

Brain Injury and Inflammation and Placental Inflammation in Response to Repetitive Umbilical Cord Occlusions in the Near Term Ovine Fetus

... in brain regions of the control group animals as identified using H&E morphology similar to that we 33 and others 47 have reported in studies of induced hypoxia in ...developing brain, or alternatively, ...

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The fate of neurons after traumatic spinal cord injury in rats: a systematic review

The fate of neurons after traumatic spinal cord injury in rats: a systematic review

... Assessment of neuroprotective activities through estimating the expression of Bcl-2, an endogenous inhibitor of apoptosis, showed no sign of Bcl-2 expression in neurons of GM one day after the moderate injury. ...

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EVERY FACE HAS A STORY TO TELL

EVERY FACE HAS A STORY TO TELL

... of injury or ...cord injury training), nurses, physical therapists, occupational therapists, speech and language pathologists, dieticians and care coordinators will work with you and your family to provide ...

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Early decompressive craniectomy and duraplasty for refractory intracranial hypertension in children: results of a pilot study

Early decompressive craniectomy and duraplasty for refractory intracranial hypertension in children: results of a pilot study

... A unilateral or bilateral fronto-temporo-parietal craniectomy was performed depending on the extent and location of the brain swelling. The removed bone flap was stored by kryo- preservation until secondary ...

6

Geriatric head injuries: impact and outcomes

Geriatric head injuries: impact and outcomes

... shear injury, weakened musculature in the neck and trunk; such that even ground-level falls are not well braced by the body, pre-existing conditions, and medications such as ...

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Neurodegeneration and Sensorimotor Deficits in the Mouse Model of Traumatic Brain Injury

Neurodegeneration and Sensorimotor Deficits in the Mouse Model of Traumatic Brain Injury

... Traumatic brain injury (TBI) can result in persistent sensorimotor and cognitive deficits, which occur through a cascade of deleterious pathophysiological events over ...vivo model of fluid ...

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A Guide to the Traumatic Brain Injury Model Systems National Database

A Guide to the Traumatic Brain Injury Model Systems National Database

... Pre-injury conditions/limitations. This variable was added in 2005 and is based on questions from the long form of the 2000 Decennial Census. Pre-injury conditions visual impairment, hearing impairment, or ...

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Time Course of Axial and Radial Diffusion Kurtosis of White Matter Infarctions: Period of Pseudonormalization

Time Course of Axial and Radial Diffusion Kurtosis of White Matter Infarctions: Period of Pseudonormalization

... We categorized the lesions into 4 groups according to DWI: perforator infarctions, white matter territorial infarctions, corti- cal infarctions, and watershed infarctions. “Perforator infarc- tions” were defined as ...

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CCL11 promotes migration and proliferation of mouse neural progenitor cells

CCL11 promotes migration and proliferation of mouse neural progenitor cells

... Fig. 3 Isolation of NPCs and migration assay. a The neurosphere from embryonic and infant mouse brains. Genes involved in proliferation and multipotency were expressed in cultured NPCs. Scale bar = 50 μ m. b ...

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