Brain microvascular endothelial cell
Uptake of Neisserial autotransporter lipoprotein (NalP) promotes an increase in human brain microvascular endothelial cell metabolic activity
... increase in human brain microvascular endothelial cell metabolic activity.. Dufailu, Jafar Mahdavi, Dlawer A.[r] ...
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Growth-factor reduced Matrigel source influences stem cell derived brain microvascular endothelial cell barrier properties
... stem cell-based models of the human BBB brought a com- plementary approach to other in vitro models based on human primary cultures or on the hCMEC/D3 immor- talized cell line [7–9, 11, ...
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Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates
... of action (contact, cytoadherence and/or soluble factors). RBC parasitized-3D7 strain (in vitro maintained culture) and uninfected RBC were used respectively as positive and negative controls for both adherence and ...
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Human blood brain barrier receptors for Alzheimer's amyloid beta 1 40 Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer
... human brain capillaries. Human brain capillaries were isolated from small fragments of cerebral cortex obtained from surgi- cal resections from three adults with seizure disorder, as we recently described ...
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Brain microvascular endothelial cell association and distribution of a 5 nm ceria engineered nanomaterial
... in cell culture media and development of the protein corona in ...ceria brain capillary cell association, potential brain entry, and ...situ brain perfusion tech- nique is a good ...
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Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation
... BMEC: brain microvascular endothelial cell; cAMP: cyclic adenosine monophosphate; cnI: collagen I; cnI/gn: genipin treated collagen I; cnIV: collagen IV; dhBMEC: derived human brain ...
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Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2
... mouse brain microvascular endothelial ...the brain, tight junction proteins such as claudin-5 and occludin at the lateral apical mem- brane establish a high-resistance paracellular barrier to ...
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A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier
... (3-D) cell culture model of human BBB microvascular endothelial cells and to apply this model to the study of RNA ...human brain microvascular endothelial cells (HBMEC) (9), an ...
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In vitro characterization of pralidoxime transport and acetylcholinesterase reactivation across MDCK cells and stem cell-derived human brain microvascular endothelial cells (BC1-hBMECs)
... h, cell monolayers were immersed in fresh HBSS for 30 min to remove any traces of ...side. Cell monolayers with test solutes were incubated at 37 °C with 5 % CO 2 on a rocker to ensure good ...
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Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendo- thelial migration of human breast cancer cell lines
... cancer cell lines across a tight barrier of primary human brain microvascular endothelia and an associated matrigel layer, and that this was at least partly mediated by MMPs (Figure ...three ...
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ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells
... and brain endothelial cells were transduced with Ad-ATF4 or treated with 250 ng/ml of LPS for 24 ...from endothelial culture and added to cultured THP-1 ...ATF4-overexpressing endothelial ...
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Post mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells
... Several lines of evidence suggest that early diagnosis of GAE due to B. mandrillaris may help successful therapy. This is supported by recent studies of Deetz et al. (2003), who have shown that early initiation of ...
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Angiotensin receptors and β catenin regulate brain endothelial integrity in malaria
... to endothelial cells in the brain, disruption of the blood-brain barrier, and cerebral ...the endothelial disruptions underlying this complication, which is responsible for the majority of ...
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Brain microvascular endothelial astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood brain barrier model
... human brain endothelial cells and astrocytes (German et ...human brain endothelial cells and cross the ...in endothelial cells, followed by an effective shut-down, may explain the di ff ...
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CD4+ T-cell Mediated Microvascular Endothelial Cell Death and Chronic Cardiac Allograft Rejection Involves Necroptosis
... many cell types and pathological conditions, including kidney tubular epithelial cells 181-183 and retinal ganglion cells 184,185 of the ischemia reperfusion injury model, 183,186,187 traumatic brain and ...
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Effects of Lipopolysaccharide and Mannheimia haemolytica Leukotoxin on Bovine Lung Microvascular Endothelial Cells and Alveolar Epithelial Cells
... Inflammatory mediator production. A real-time reverse transcription-PCR (RT-PCR) was used to determine the changes in the levels of expression of the inflammatory mediators IL-1 ␣ , IL-1  , IL-8, and tumor necrosis ...
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HIV 1 associated dementia: symptoms and causes
... opportunistic brain infections such as cryptococcus, Toxoplasma gondii, JC virus, cytomegalovirus, Epstein-Barr virus, Varicella zoster virus, and human herpes virus type 6 ...
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Basement membrane and blood–brain barrier
... The blood–brain barrier (BBB) is a highly complex and dynamic structure, mainly composed of brain microvascular endothelial cells, pericytes, astrocytes and the basement membrane (BM). The ...
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Targeting Early Dementia: Using Lipid Cubic-Phase Nanocarriers to Cross the Blood-Brain Barrier
... transcytosis of HDL across brain microvascular endothelial cells (i.e., across the blood- 107.. brain barrier).. The authors assert that elucidating the mechanisms of HDL transcytosis 1[r] ...
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Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
... Cell and tissue lysates (prepared as described above) were assayed by Precision Red Advanced Protein Reagent to assess total protein concentration. Equal quantities of protein were aliquoted, and samples were ...
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