Brain microvascular endothelial cells (BMECs)
Flavin Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells
... rat brain microvascular endothelial cells (BMECs), which constitute the blood-brain barrier (BBB), and whether N-oxide from the tertiary amine, d-chlorpheniramine, was formed by ...
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Effects of Neospora caninum infection on brain microvascular endothelial cells bioenergetics
... Disruption of cellular Δψm has been demonstrated to be a causative factor for the occurrence of necrosis and apoptosis, and is often associated with oxidative stress [36]. Mitochondrial staining showed that N. caninum ...
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Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D
... the cells were switched to dhBMEC medium for 2 ...of endothelial cell serum-free medium supplemented with 1% platelet- poor plasma-derived human serum (Sigma), 2 ng mL ...
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The complete genome sequence of Cronobacter sakazakii ATCC 29544T, a food-borne pathogen, isolated from a child’s throat
... with the invasion of human brain microvascular endothelial cells (BMECs). In addition, gene clusters for siderophore production (iucABCD/iutA) and the related transport system (eitCBAD) ...
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Blood brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease
... human brain microvascular endothelial cells (BMECs), a human blood-brain barrier (BBB) model system, at much greater efficiency than do ...human BMECs was abrogated by ...
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Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells
... mans cells may become trapped within the microvessels in the brain, and subsequently, enter into the brain through the parenchyma ...fungal cells to endothelial cells ...
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Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF
... Elevated levels of cytokines/chemokines contribute to increased neuroinvasion of human immunodeficiency virus type 1 (HIV-1). Previous work showed that lipopolysaccharide (LPS), which is present in the plasma of patients ...
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Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells
... of brain microvascular endothelial cells (BMECs), which strictly regulate molecular transport between the bloodstream and the brain to ensure proper function of neuronal cir- ...
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Alpha7 nicotinic acetylcholine receptor is required for blood brain barrier injury related CNS disorders caused by Cryptococcus neoformans and HIV 1 associated comorbidity factors
... Abbreviations AIDS: Acquired immune deficiency syndrome; α7 nAChR: Alpha7 nicotinic acetylcholine receptor; BBB: Blood-brain barrier; BMEC: Brain microvascular endothelial Cells; CAPE: C[r] ...
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Basement membrane and blood–brain barrier
... The blood–brain barrier (BBB) is a highly complex and dynamic structure, mainly composed of brain microvascular endothelial cells, pericytes, astrocytes and the basement membrane (BM). ...
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Targeting Early Dementia: Using Lipid Cubic-Phase Nanocarriers to Cross the Blood-Brain Barrier
... transcytosis of HDL across brain microvascular endothelial cells (i.e., across the blood- 107.. brain barrier).. The authors assert that elucidating the mechanisms of HDL transcytosis 1[r] ...
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p54nrb, a PSF Protein Partner, Contributes to Meningitic Escherichia coli K1 Mediated Pathogenicities
... vitro brain microvascular endothelial cells (BMEC) culture model with characteris- tics of the BBB has been established for dissecting the molecular and cellular mechanisms of ...
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CXC and CC Chemokine Receptors on Coronary and Brain Endothelia
... Materials and Methods: The expression of chemokine receptors in human brain microvascular endothelial cells (BMVEC) and coronary artery endothelial cells (CAEC).. in vitro and cryostat s[r] ...
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Angiotensin receptors and β catenin regulate brain endothelial integrity in malaria
... blood cells (Pf-iRBCs) to endothelial cells in the brain, disruption of the blood-brain barrier, and cerebral ...the endothelial disruptions underlying this complication, which ...
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Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
... human brain vascular pericytes as evidenced by several ...mRNA. Brain pericytes were fully permissive for CMV lytic replication after 72 to 96 hours in culture compared to human astrocytes or human ...
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A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier
... BBB microvascular endothelial cells and to apply this model to the study of RNA ...human brain microvascular endothelial cells (HBMEC) (9), an immortalized human BBB ...
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Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates
... sponse, endothelial cell (EC) activation, and altered hemostasis can lead to blood pulmonary/brain barrier impairment ...in brain microvessels, espe- cially pRBC expressing PfEMP-1 domain cassettes 8 ...
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ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells
... lial cells, which in turn promotes monocyte/macrophage adhesion and migration into retinal tissue resulting in in- ...and brain endothelial cells were transduced with Ad-ATF4 or treated with ...
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Differential Replication of Pathogenic and Nonpathogenic Strains of West Nile Virus within Astrocytes
... WNV-positive cells were detected at 12 h postinfection in WNV-NY-infected ...antigen-positive cells were not detected in WNV- MAD78-infected cultures until 16 h postinfection, which is con- sistent with the ...
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Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease
... Taken together these studies support the notion that HCMV infection of retinal pericytes is a lytic infection that would result in pericyte loss at proximal sites within the IBRB. This would have implications for retinal ...
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