Brain Targeting
Theranostic liposomes loaded with quantum dots and apomorphine for brain targeting and bioimaging
... Multifunctional liposomes can be used to deliver various agents such as fluorescence probes and therapeutics. We developed theranostic liposomes with high encapsulation of QDs and apomorphine, which improved fluorescence ...
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SLN BRAIN TARGETING DRUG DELIVERY FOR CNS: A NOVEL APPROACH
... The brain is a delicate organ and nature has very efficiently protected ...it. Brain is protected by presence of two barrier systems BBB (Blood Brain Barrier) and BCSFB (Blood Cerebrospinal Fluid ...
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Effect of surface modification of solid lipid nanoparticles in brain targeting
... blood brain barrier (BBB) is limited because of p-gp, acts as an efflux pump to limit the drug transport to brain (Kemper et ...induced brain metastasis is ...and brain targeting ...
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Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood–brain barrier transport investigations
... Abstract: Delivering drugs to intracerebral regions can be accomplished by improving the capacity of transport through blood–brain barrier. Using sertraline as model drug for brain targeting, the ...
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Effect of Surfactant Coating on Brain Targeting Polymeric Nanoparticles; a Review
... to brain is one of the most challenging issues for pharmaceutical research as blood- brain barrier acts as an insurmountable obstacle for the passage of systemically delivered therapeutics and the ...
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POLYMER -LIPID HYBRID NANOPARTICLES FOR BRAIN TARGETING THROUGH INTRANASAL DELIVERY
... Brain targeting is a difficult task due to various factors; those factors can restricts the entry of drugs into the brain, in present study polymer-lipid hybrid nanoparticles were prepared for ...
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THERMOSENSITIVE GELS CONTAINING CARBAMAZEPINE MICROSPHERES FOR INTRANASAL BRAIN TARGETING
... Context: Carbamazepine, derived from tricyclic antidepressant drugs is one of the most widely used antiepileptic drugs. It is characterized by a considerable hepatic first-pass effect owing to the enzymatic auto- ...
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Brain-targeting study of stearic acid–grafted chitosan micelle drug-delivery system
... A number of attempts have been made to overcome the barrier. Various nanoparticle delivery systems were designed for brain targeting, including liposomes, solid lipid nano- particles, and polymeric ...
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“EVALUATION OF BRAIN-TARGETING FOR THE NASAL DELIVERY OF MIDAZOLAM” by Sapna Desai, Gali Vidyasagar, Anil Bhandhari, India.
... the brain circumventing the brain-barriers following intranasal administration provides a unique feature and better option to target drugs to ...to brain drug delivery and the use of bioadhesive ...
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Brain targeting drug delivery system
... gene targeting have been receiving attention in the field of drug delivery and targeting because of the high drug loading capacity ...effective targeting of micelles systems to the brain by ...
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Solid Lipid Nanoparticles for Brain Targeting
... region of cerebrum. cerebral cortex is again divided into four lobes Frontal lobe, Parietal lobe, Occipital lobe, Temporal lobe functions of cerebrum are sensory processing, determines the intelligence of the being, ...
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PRELIMINARY INVESTIGATION INTO COMPARATIVE TRANSCRANIAL BRAIN TARGETED AND TRANSDERMAL SYSTEMIC EFFECTS OF DIAZEPAM ON SLEEP LATENCY
... the brain are a potential route for targeted central nervous system drug ...investigate brain targeting in human ...transcranial brain targeting of diazepam is ...
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AN OVERVIEW ON EXPLORING NASAL MICROEMULSION FOR TREATMENT OF CNS DISORDERS
... for brain targeting as brain and nose compartments are connected to each other via olfactory/ trigeminal route via peripheral ...to brain transport and the therapeutic viability of the route ...
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Development of high drug-loading nanomicelles targeting steroids to the brain
... the brain, for the first time, has been proved to be an effective neuroprotective steroid by our previous ...into brain-targeting ...mouse brain delivered by lactoferrin-modified nanomicelles ...
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Penetration of blood–brain barrier and antitumor activity and nerve repair in glioma by doxorubicin-loaded monosialoganglioside micelles system
... In this study, ganglioside GM1 micelles were designed and synthesized. The anticancer drug DOX was spontaneously encapsulated into the nanomicelles. In aqueous solution, the mixed micelles self-assembled into spherical ...
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A Conceptual Review on Micro Bubbles
... the brain by scientists, certain brain targeting approaches have been developed during recent ...webs targeting the brain cells, Avidin-Biotin Technology, genetically engineered ...
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IN VIVO METHODS TO STUDY UPTAKE OF NANOPARTICLES INTO THE BRAIN
... recent brain targeting studies involving nanoparticles, a wide range of approaches has been used by researchers to determine the extent, rate, and effect of drug and nanoparticle uptake into the ...the ...
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NANOCARRIER FOR INTRANASAL ADMINISTRATION
... to brain or central nervous system (CNS) due to complex ...for brain targeting, as the nose and brain compartments are connected to each other via the olfactory route and via peripheral ...the ...
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Surface modification of gold nanoparticles with neuron-targeted exosome for enhanced blood–brain barrier penetration
... to brain cells. Here, we report the surface modification of AuNPs with brain- targeted exosomes derived from genetically engineered mammalian cells by using the mechanical method or extrusion to create ...
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Calcium Signaling in Brain Cancers: Roles and Therapeutic Targeting
... Despite improving the survival rate of patients, current therapies pose serious complications that impact quality of life in patients. Traumatic injuries such as damage to blood vessels and ischemia are common problems ...
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