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Branched-chain

Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis

Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis

... Our study has several strengths. First, the nested case-control study design, where the participants were drawn from existing cohort studies, minimizes the risk of selection bias when choosing the controls. Second, the ...

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The Complex Role of Branched Chain Amino Acids in Diabetes and Cancer

The Complex Role of Branched Chain Amino Acids in Diabetes and Cancer

... Diabetes and cancer come with widespread metabolic perturbations that affect the entire body and the branched chain amino acids appear to be among the most distinctly perturbed metabolites. Given the ...

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Role of branched-chain amino acid transporters in Staphylococcus aureus virulence

Role of branched-chain amino acid transporters in Staphylococcus aureus virulence

... three branched-chain amino acids (BCAAs), leucine, isoleucine, and valine, are the most hydrophobic of the amino acids and are involved in determining the structures of several globular ...

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Novel metabolic and physiological functions of branched chain amino acids: a review

Novel metabolic and physiological functions of branched chain amino acids: a review

... above, but rather was comprised of the BCAA, the aro- matic amino acids, C3 and C5 acylcarnitines (Fig. 1), as well as glutamate and alanine. Concurrently, recent metabolomics conducted with 2,422 normoglycemic in- ...

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Distribution of branched chain alpha keto acid dehydrogenases in primate tissues

Distribution of branched chain alpha keto acid dehydrogenases in primate tissues

... The specific activity of the branched-chain alpha-keto acid (BCKA) dehydrogenases was measured in normal tissues of the rat, monkey, and man, and in cirrhotic human liver. In the rat, specific activity of ...

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Branched chain amino acids (bcaa) supplementation increases the skeletal muscle protein synthesis under calorie restricted condition  after endurance exercise

Branched chain amino acids (bcaa) supplementation increases the skeletal muscle protein synthesis under calorie restricted condition after endurance exercise

... of Branched Chain Amino acids (BCAA’s) under CR condition on protein metabolism and physical performance could signify the importance of adequate caloric ...

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Computer Simulation of Torsional Vibrations of Branched Chain Topology Systems

Computer Simulation of Torsional Vibrations of Branched Chain Topology Systems

... In this paper, the algorithm for branched chain topology torsional systems based on the transfer matrix method is given 111, 131. It was on this basis that the computer program named TORZIJA was developed ...

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MAPLE SYRUP URINE DISEASE: BRANCHED-CHAIN KETO-ACIDURIA

MAPLE SYRUP URINE DISEASE: BRANCHED-CHAIN KETO-ACIDURIA

... oxidative decarboxylation of the branched- chain amino acids appear to be generally distributed in tissues (Table III). It was[r] ...

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Myocardial protein turnover in patients with coronary artery disease  Effect of branched chain amino acid infusion

Myocardial protein turnover in patients with coronary artery disease Effect of branched chain amino acid infusion

... of branched chain amino acid (BCAA) infusion on heart protein turnover and on the myocardial balance of amino acids and branched chain ketoacids (BCKA) in these ...

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Intraoperative infusion of branched chain amino acids in patients undergoing gastrointestinal tumor surgery

Intraoperative infusion of branched chain amino acids in patients undergoing gastrointestinal tumor surgery

... Unlike other amino acids (AAs) that are metabo- lized dominantly in the liver, the branched-chain amino acids (BCAA), isoleucine, leucine, and valine are uniquely metabolized primarily in the skeletal ...

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Combined effect of branched-chain amino acids and taurine supplementation on delayed onset muscle soreness and muscle damage in high-intensity eccentric exercise

Combined effect of branched-chain amino acids and taurine supplementation on delayed onset muscle soreness and muscle damage in high-intensity eccentric exercise

... AEx: Immediately after exercise; ANOVA: Analysis of variance; AUC: Area under the curve; BA: Branched-chain amino acid and placebo 2 supplementation group; BCAA: Branched-chain amino aci[r] ...

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BIOCHEMICAL STUDIES ON A VARIANT OF BRANCHED CHAIN KETOACIDURIA IN A 19-YEAR-OLD FEMALE

BIOCHEMICAL STUDIES ON A VARIANT OF BRANCHED CHAIN KETOACIDURIA IN A 19-YEAR-OLD FEMALE

... Pediatrics, 48:795, 1971, BRANCHED CHAIN KETOACWURIA, MAPLE SYRUP URINE DISEASE, LEUCINE, VALINE, ISOLEUCINE, GE- NETIC VARIANT.. I N 1954 a severe early fatal neurologic.[r] ...

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Branched chain amino acids: Passive biomarkers or the key to the pathogenesis of cardiometabolic diseases?

Branched chain amino acids: Passive biomarkers or the key to the pathogenesis of cardiometabolic diseases?

... Branched chain amino acid catabolism impairment in 1 or more tissues, changes in cellular uptake from the blood, increases in proteolysis, IR or excessive intake have been identified as potential causes of  ...

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THE DIAGNOSIS OF MAPLE SYRUP URINE DISEASE (Branched-chain Ketoaciduria)

THE DIAGNOSIS OF MAPLE SYRUP URINE DISEASE (Branched-chain Ketoaciduria)

... Ketoaciduria): BY THE IN VITRO STUDY OF THE PERIPHERAL LEUKOCYTE THE DIAGNOSIS OF MAPLE SYRUP URINE DISEASE (Branched-chain. http://pediatrics.aappublications.org/content/32/2/234[r] ...

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Modular pathway engineering for the microbial production of branched-chain fatty alcohols

Modular pathway engineering for the microbial production of branched-chain fatty alcohols

... from branched-chain fatty acids ...gous branched-chain α-keto acid dehydrogenase complex (BKD), a branched-chain-acyl-CoA-specific β-ketoacyl- acyl-carrier protein (FabH) and a ...

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Newborn Screening for Maple Syrup Urine Disease (Branched-Chain Ketoaciduria)

Newborn Screening for Maple Syrup Urine Disease (Branched-Chain Ketoaciduria)

... Routine newborn screening for maple syrup urine disease (MSUD) has been conducted since 1964, and.. more than 9#{189} million newborns throughout the world have been tested with use of a[r] ...

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Synthetic and enzymatic studies related to branched chain amino acid metabolism

Synthetic and enzymatic studies related to branched chain amino acid metabolism

... to carboxylic esters published The enzyme acetolactate decarboxylase ADC was found to S-isomers decarboxylate CY-acetolactate to the of analogues and its R--hydroxyketones high in optica[r] ...

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Investigations related to branched chain amino acid metabolism

Investigations related to branched chain amino acid metabolism

... The synthetic route mimics the biological action of thiamine pyrophosphate TPP in acetohydroxyacid synthase, the first enzyme of the valine-isoleucine biosynthetic pathway.. The syntheti[r] ...

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Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations

Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations

... the branched-chain-aminotransferase (BCAT) enzyme, in which α-ketoglutarate receives an amino group from the BCAA, producing glutamate and a branched-chain keto acid ...the ...

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Investigation into the pigmentation and membrane structure of sarcina aurantiaca

Investigation into the pigmentation and membrane structure of sarcina aurantiaca

... branched chain amino acid composition of the medixim, can also specifically affect the synthesis of branched chain fatty acids in some bacteria Tornabene, Bennett and Oro, 1967; ICaneda,[r] ...

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