Bronchial Epithelial-Cells
Original Article Astragalus extract inhibits TGF-β1-induced EMT of bronchial epithelial cells and airway remodeling in asthmatic mice
... that Epithelial-mesenchymal transition (EMT) of bronchial epithelial cells was an important source of myofibroblast in asthmatic mice ...differentiated epithelial cells undergo a ...
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Vulnerability of the human airway epithelium to hyperoxia Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress
... oxidant stress. The basis for this limited gene expression was examined by evaluation of the expression of the endogenous gene in human bronchial epithelial cells in response to hyperoxia. Hyperoxia ...
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Human H7N9 virus induces a more pronounced pro inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically linked chicken H7N9 virus
... human bronchial epithelial cells ...H7N9-HU-infected cells suggest that H7N9-HU has acquired additional characteristics that enhance the virulence in ...
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Matriptase Proteolytically Activates Influenza Virus and Promotes Multicycle Replication in the Human Airway Epithelium
... human epithelial cells and within endosomes, and we showed that the soluble form of the protease was able to specifically cleave hemagglutinins from H1 virus, but not from H2 and H3 viruses, in a broad pH ...
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Respiratory Syncytial Virus Infection, TLR3 Ligands, and Proinflammatory Cytokines Induce CD161 Ligand LLT1 Expression on the Respiratory Epithelium
... in bronchial ep- ithelial cells in response to TLR ...sion, cells were stimulated with 10 g/ml poly(I·C) for 1, 2, 4, 8, 16, 24, 48, and 72 h, and mRNA expression was analyzed by quan- titative ...
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Original Article Expression of miR-32 in human non-small cell lung cancer and its correlation with tumor progression and patient survival
... normal bronchial epithelial cells, 90 pairs of tumor samples and adjacent non-tumor tis- ...normal bronchial epithelial cells and adja- cent non-tumor ...
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Gene and protein expression of tlr 9 with lipopolysaccharide in human bronchial epithelial cells
... The aim of the study was to know whether Toll like receptor 9 (TLR9) is expressed when the human bronchial epithelial cells were induced with Lipopolysaccharide. The gene and protein expression ...
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Cytopathogenesis of Sendai Virus in Well-Differentiated Primary Pediatric Bronchial Epithelial Cells
... pediatric bronchial epithelial cells ...basal cells and intact tight ...nonciliated cells, not goblet cells, on the apical ...
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A(H7N9) Virus Results in Early Induction of Proinflammatory Cytokine Responses in both Human Lung Epithelial and Endothelial Cells and Shows Increased Human Adaptation Compared with Avian H5N1 Virus
... primary bronchial and tracheal epithelial cells, targeting both ciliated and mucin-secretory cells, providing greater insight into the cellular tropism of this novel ...human bronchial ...
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Rhinovirus Activates Interleukin-8 Expression via a Src/p110β Phosphatidylinositol 3-Kinase/Akt Pathway in Human Airway Epithelial Cells
... human bronchial epithelial cells with RV39 induces rapid activation of PI 3-ki- nase and phosphorylation of the PI 3-kinase p85 ␣ regulatory subunit ...human bronchial epithelial ...
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Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells
... airway epithelial cells, since several reports have concluded that HSPGs are not localized on the ciliated apical side of fully differ- entiated bronchial epithelial cells cultured at ...
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Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry
... 293T/17 cells, obtained from the ATCC (CRL-11268) with the expression plasmid, followed by incubation at 37°C for 30 to 36 ...These cells were then infected with VSV[Delta]G-G, which encodes the VSV-G ...
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Modulation of airway inflammation in cystic fibrosis In vivo suppression of interleukin 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
... Based on the knowledge that neutrophil elastase (NE) in cystic fibrosis (CF) epithelial lining fluid (ELF) can induce human bronchial epithelial cells to express the gene for interleukin 8 ...
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Human Pulmonary Microvascular Endothelial Cells Support Productive Replication of Highly Pathogenic Avian Influenza Viruses: Possible Involvement in the Pathogenesis of Human H5N1 Virus Infection
... endothelial cells are affected by HPAI H5N1 virus infec- ...endothelial cells (HULEC and HMVEC-LBI) resulted in less CPE and cell death observed microscopically than those previously observed in infected ...
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Original Article miR-330 regulates interleukin-13-induced MUC5AC secretion by targeting Munc18b in human bronchial epithelial cells
... human bronchial epithelial cells ...HBE16 cells inhibited IL-13-induced MUC5AC secretion while, conversely, depletion of endogenous miR-330 exacerbated MUC5AC ...HBE16 cells by acting ...
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Allergen induced IL 9 directly stimulates mucin transcription in respiratory epithelial cells
... Th2 cells as being instrumental in the generation of mucin-containing epithelial cells in allergic airways (17, ...in epithelial cells or acted through an intermediate cell ...
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Synergistic Upregulation of Interleukin-8 Secretion from Pulmonary Epithelial Cells by Direct and Monocyte-Dependent Effects of Respiratory Syncytial Virus Infection
... of epithelial cells and macrophages by RSV (3, 10, 11, 31, ...Such cells may also contribute to subsequent chemo- kine ...epithelial cells. RSV-CM caused only a 2-fold increase in ...
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Influenza Virus Infection Increases p53 Activity: Role of p53 in Cell Death and Viral Replication
... virus-infected cells. In primary human lung cells, influenza virus increased p53 protein ...A549 cells inhibited influenza virus-induced cell death as measured by trypan blue exclusion and caspase ...
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Vesicular Stomatitis Virus G-Pseudotyped Lentivirus Vectors Mediate Efficient Apical Transduction of Polarized Quiescent Primary Alveolar Epithelial Cells
... primary cells compared to standard murine retrovirus vec- tors, has raised concerns regarding inadvertent production of replication-competent ...transduced cells in animal models ...
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Adenoviral mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo
... distal epithelial cells in cultured fetal lung tissues from rodents and humans diffusely expressed the lacZ transgene 3 d after viral ...tracheal, bronchial, and distal pulmonary epithelial ...
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